Fostering a transport policy paradigm shift: comprehensiveness, sustainability and co-modality

This issue of the FAL Bulletin proposes a paradigm shift away from the traditional approach to transport policy in the region, so as to better address issues associated with development. It suggests working towards an integrated and sustainable infrastructure, logistics and mobility policy structure based on the principle of co- modality.

Convergence and divergence of transport and mobility policies in Latin America: Lack of urban co-modality

This issue of the FAL bulletin analyses transport and mobility policy in Latin America, where the lack of integrated public policies for urban mobility and the failure to take coordinated action over time make it difficult to prioritize investments and coordinate existing initiatives (both public and private).

Institutional framework, co-modality and sustainable transport services

This issue of the FAL bulletin focuses on the problems which public institutions encounter when formulating transport policies and the challenge of designing and implementing systemic, integrated, sustainable transport policies in the current institutional framework in the countries of Latin America.

The expressibility of modality in representational complement clauses in Brazilian Portuguese

This paper deals with the (im)possibility of expressing a variety of modal categories within the context of the layering approach to complementation in Functional Discourse Grammar (FDG).Our hypothesis is that modal expressions in complement clauses only pertain to operator or modifier classes of the highest layer relevant for that type of embedded construction and for all lower levels. In order to test this hypothesis, occurrences of complement clauses in two databases of spoken Brazilian Portuguese are analyzed. The investigation of this hypothesis is restricted to representational complement clauses.

Beta therapy with 90 strontium as single modality therapy for canine squamous cell carcinoma in third eyelid

The purpose was to evaluate the effectiveness of beta-radiation with strontium-90 as single modality treatment of canine third eyelid squamous cell carcinoma (SCC). Nine dogs diagnosed with third eyelid SCC were treated with strontium-90. Radiation therapy was administered in four fractions of 100cGy per site every four days and at a depth of 0.2cm (Strontium-90 build' up) in each fraction. Radiation with beta therapy was well tolerated in all animals with no occurrence of radiation induced cataracts. In all cases, there were increased signs of conjunctival inflammation around the mass, which subsided with topical anti-inflammatory. Two dogs required surgical treatment for local tumor recurrence at 150 days and 352 days. In the remaining seven cases, disease free interval ranged from 1239 days to 2555 days. Beta therapy using 90Sr may be a valid alternative for the treatment of third eyelid SCC in dogs

Uma investigação funcional do verbo modal deber no espanhol falado peninsular

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A study of epistemic modality in academic and popularised discourse: the case of possibility adverbs perhaps, maybe and possibly

[EN] This paper describes the use of perhaps, maybe and possibly in a cross-disciplinary corpus of academic and popularised scientific writing. It accounts for their higher frequency in popularised discourse by investigating their functions in detail. The analysis, conducted from various perspectives (syntactic, semantic, pragmatic and rhetorical), suggests that two factors are at work: the evidential basis for the epistemic assessment and the mode of discourse the marker is most closely associated with.

A contrastive analysis of epistemic modality in scientific English

[ES] This paper investigates the use of epistemic expressions in scientific English. The main aim of this research is to analyse if native speakers of English use epistemic modality in the same way than non-native speakers of English and to detect the most outstanding cognitive implications of this fact. The corpus used in this research contains 50 research papers written by native English speakers and 50 scientific papers written by Spanish researchers who use English to communicate internationally. As epistemic modals are used to indicate the possibility of some piece of knowledge, this paper focuses on epistemic modal verbs in order to detect if native speakers of English and non-native speakers of English communicate modality in the same way, or if there are differences in frequency and use. The results obtained in this analysis indicated that there are differences in the frequency of use of epistemic expressions, even if the intention of the writers is the same.

Non-normal modal logics, quantification, and deontic dilemmas. A study in multi-relational semantics

This dissertation is devoted to the study of non-normal (modal) systems for deontic logics, both on the propositional level, and on the first order one. In particular we developed our study the Multi-relational setting that generalises standard Kripke Semantics. We present new completeness results concerning the semantic setting of several systems which are able to handle normative dilemmas and conflicts. Although primarily driven by issues related to the legal and moral field, these results are also relevant for the more theoretical field of Modal Logic itself, as we propose a syntactical, and semantic study of intermediate systems between the classical propositional calculus CPC and the minimal normal modal logic K.

Combined modality treatment improves tumor control and overall survival in patients with early stage Hodgkin's lymphoma: a systematic review

Combined modality treatment (CMT) of chemotherapy followed by localized radiotherapy is standard treatment for patients with early stage Hodgkin's lymphoma. However, the role of radiotherapy has been questioned recently and some clinical study groups advocate chemotherapy only for this indication. We thus performed a systematic review with meta-analysis of randomized controlled trials comparing chemotherapy alone with CMT in patients with early stage Hodgkin's lymphoma with respect to response rate, tumor control and overall survival (OS). We searched Medline, EMBASE and the Cochrane Library as well as conference proceedings from January 1980 to February 2009 for randomized controlled trials comparing chemotherapy alone versus the same chemotherapy regimen plus radiotherapy. Progression free survival and similar outcomes were analyzed together as tumor control. Effect measures used were hazard ratios for OS and tumor control as well as relative risks for complete response (CR). Meta-analyses were performed using RevMan5. Five randomized controlled trials involving 1,245 patients were included. The hazard ratio (HR) was 0.41 (95% confidence interval (CI) 0.25 to 0.66) for tumor control and 0.40 (95% CI 0.27 to 0.59) for OS for patients receiving CMT compared to chemotherapy alone. CR rates were similar between treatment groups. In sensitivity analyses another 6 trials were included that did not fulfill the inclusion criteria of our protocol but were considered relevant to the topic. These trials underlined the results of the main analysis. In conclusion, adding radiotherapy to chemotherapy improves tumor control and OS in patients with early stage Hodgkin's lymphoma.

Dual-modality PET/CT instrumentation-today and tomorrow

Positron emission tomography (PET) has proven to be a clinically valuable imaging modality, particularly for oncology staging and therapy follow-up. The introduction of combined PET/CT imaging has helped address challenging imaging situations when anatomical information on PET-only was inadequate for accurate lesion localization. After a decade of PET/CT these combined systems have matured technically. Today, whole-body oncology staging is available with PET/CT in 15 min, or less. This review details recent developments in combined PET/CT instrumentation and points to implications for major applications in clinical oncology.