Climate change, ethics and human security.

Este texto, escrito por expertos internacionales, sostiene que el cambio climático debe considerarse como una cuestión de seguridad humana y no como un problema ambiental que pueda gestionarse en solitario. Muestra el concepto de seguridad humana con un nuevo enfoque ligado a los desafíos que el cambio climático ofrece a la humanidad, así como da respuestas para un futuro más equitativo y sostenible para las próximas generaciones. El cambio climático, la ética y la seguridad humana serán de interés para los investigadores, los responsables políticos y los profesionales interesados con las dimensiones humanas del cambio climático, así como para los estudiantes de nivel superior en ciencias sociales y humanidades preocupados por este problema.

Development and simultaneous application of multiple care protocols in critical care: a multicenter feasibility study

OBJECTIVE: To test the feasibility of and interactions among three software-driven critical care protocols. DESIGN: Prospective cohort study. SETTING: Intensive care units in six European and American university hospitals. PATIENTS: 174 cardiac surgery and 41 septic patients. INTERVENTIONS: Application of software-driven protocols for cardiovascular management, sedation, and weaning during the first 7 days of intensive care. MEASUREMENTS AND RESULTS: All protocols were used simultaneously in 85% of the cardiac surgery and 44% of the septic patients, and any one of the protocols was used for 73 and 44% of study duration, respectively. Protocol use was discontinued in 12% of patients by the treating clinician and in 6% for technical/administrative reasons. The number of protocol steps per unit of time was similar in the two diagnostic groups (n.s. for all protocols). Initial hemodynamic stability (a protocol target) was achieved in 26+/-18 min (mean+/-SD) in cardiac surgery and in 24+/-18 min in septic patients. Sedation targets were reached in 2.4+/-0.2h in cardiac surgery and in 3.6 +/-0.2h in septic patients. Weaning protocol was started in 164 (94%; 154 extubated) cardiac surgery and in 25 (60%; 9 extubated) septic patients. The median (interquartile range) time from starting weaning to extubation (a protocol target) was 89 min (range 44-154 min) for the cardiac surgery patients and 96 min (range 56-205 min) for the septic patients. CONCLUSIONS: Multiple software-driven treatment protocols can be simultaneously applied with high acceptance and rapid achievement of primary treatment goals. Time to reach these primary goals may provide a performance indicator.

Building Up: A history of Montana Tech Library 1900 - 2006

This paper traces the history of the Library of the Montana State School of Mines from its inception in 1900 to 2006. The history includes sketches of the library directors over 106 years, and the library’s various campus locations and emerging collections and services.

General distress, hopelessness—suicidal ideation and worrying in adolescence: Concurrent and predictive validity of a symptom-level bifactor model for clinical diagnoses

BACKGROUND: Clinical disorders often share common symptoms and aetiological factors. Bifactor models acknowledge the role of an underlying general distress component and more specific sub-domains of psychopathology which specify the unique components of disorders over and above a general factor. METHODS: A bifactor model jointly calibrated data on subjective distress from The Mood and Feelings Questionnaire and the Revised Children's Manifest Anxiety Scale. The bifactor model encompassed a general distress factor, and specific factors for (a) hopelessness-suicidal ideation, (b) generalised worrying and (c) restlessness-fatigue at age 14 which were related to lifetime clinical diagnoses established by interviews at ages 14 (concurrent validity) and current diagnoses at 17 years (predictive validity) in a British population sample of 1159 adolescents. RESULTS: Diagnostic interviews confirmed the validity of a symptom-level bifactor model. The underlying general distress factor was a powerful but non-specific predictor of affective, anxiety and behaviour disorders. The specific factors for hopelessness-suicidal ideation and generalised worrying contributed to predictive specificity. Hopelessness-suicidal ideation predicted concurrent and future affective disorder; generalised worrying predicted concurrent and future anxiety, specifically concurrent generalised anxiety disorders. Generalised worrying was negatively associated with behaviour disorders. LIMITATIONS: The analyses of gender differences and the prediction of specific disorders was limited due to a low frequency of disorders other than depression. CONCLUSIONS: The bifactor model was able to differentiate concurrent and predict future clinical diagnoses. This can inform the development of targeted as well as non-specific interventions for prevention and treatment of different disorders.

Copy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness

Acknowledgements We would like to thank all of the patients, relatives and control individuals who participated in the study. We are indebted to the late Prof. Walter Muir, Chair of Developmental Psychiatry and Honorary Consultant in Learning Disability Psychiatry, University of Edinburgh, who initiated these studies and whose work was dedicated to the welfare of the patients who generously participated. We are also grateful to Mrs. Pat Malloy for her assistance with DNA collection and MAQ assays screening of the Scottish samples. The Scottish sample collection was supported by a grant from the Chief Scientist Office (CSO), part of the Scottish Government Health and Social Care Directorates. This research was funded by grants from the CSO to B.S.P. (grant CZB/4/610), The Academy of Medical Sciences/Wellcome Trust to M.J. (grant R41455) and The RS Macdonald Charitable Trust (grant D21419 together with J.H.), the Swedish Research Council (grants 2003-5158 and 2006-4472), the Medical Faculty, Umeå University, and the County Councils of Västerbotten and Norrbotten, Sweden, as well as by grants from the Fund for Scientific Research Flanders (FWO-F), the Industrial Research Fund (IWT) and the Special Research Fund of the University of Antwerp, Belgium. M.J. is funded by a Wellcome Trust Clinical Research Fellowship for MB PhD graduates (R42811). We acknowledge the contribution of the personnel of the VIB Genetic Service Facility (http://www.vibgeneticservicefacility.be/) for the genetic analysis of the Swedish samples. Research nurses Gunnel Johansson, Lotta Kronberg, Tage Johansson and Lisbeth Bertilsson are thankfully acknowledged for their help and expertise. The Betula Study was funded by the Swedish Research Council (grants 345-2003-3883 and 315-2004-6977). We also acknowledge the contribution by the staff in the Betula project

Henry S. Frieze

Professor of Latin and acting president of the University of Michigan. On verso: North & Oswald Photographers. Toledo, Ohio. Established 1864. Take the Passenger Elevator at St. Clair Street Entrance, and Visit our New Studios, 45 Hall Block. Largest and finest in the West. All negatives preserved and Registered. Duplicates of this picture may be had at any time.

Dr. James B. Angell

President of the University of Michigan, minister to China and Turkey. On verso: North & Oswald Photographers, Toledo, Ohio. Established 1864. Take the Passenger Elevator at St. Clair Street Entrance, and Visit our New Studios, 45 Hall Block. Largest and finest in the West. All negatives preserved and Registered...

Beyond the sea-rim /

Mode of access: Internet.

The Ante-Nicene fathers. Translations of the writings of the fathers down to A.D. 325.

First published under title: Ante-Nicene Christian library.

Information pertaining to farm, home, and community : with special reference to type-of-farming area.

Errata sheets tipped in.

Oil investigations in Illinois in 1916, under direction of Fred H. Kay.

"Work in cooperation with U.S. Geological Survey."

Political sketches of the state of Europe, from 1814-1867, containing Count Ernst Münster's despatches to the Prince Regent, from the congress of Vienna.

Translated from the German (Politische skizzen über die lage Europas vom Wiener kongress bis zur gegenwart ... Leipzig, 1867) by the author's wife, Gräfin Harriet Elizabeth Münster- Ledenburg.

Modern Persian conversation-grammar, with reading lessons, English-Persian vocabulary and Persian letters;

At head of title: Method-Gaspey-Otto-Sauer.