Darjiling District, India, 1898 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Lower provinces of Bengal : district Darjeeling. It was published by Survey of India in 1898. Scale [ca. 1:253,440]. Covers Darjiling District, India.The image inside the map neatline is georeferenced to the surface of the earth and fit to the Kalianpur 1975 India Zone III projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as roads, railroads, drainage, cities and other human settlements, fortification, camping grounds, dak bungalow, tea gardens, police stations, Buddhist monasteries, ground cover, and more. Relief shown by hachures and spot heights. This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

Punjab Region, India & Pakistan, 1849 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: A new map of Punjab and protected Sikh states : including the British provinces to the South, as far as the parallel of Agra & Jessulmair. It was published by William Rushton in 1849. Scale [ca. 1:1,350,000]. Covers the Punjab region, India and Pakistan, and a portion of Afghanistan.The image inside the map neatline is georeferenced to the surface of the earth and fit to the Asia North Lambert Conformal Conic coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, cities and other human settlements, roads, territorial and administrative boundaries, and more. Relief shown by hachures.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

Bombay Harbour, India, Nautical Chart, 1806 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: A plan of Bombay harbour : principally illustrative of the entrance, constructed from measured bases, and a series of angles, taken in 1803 & 4 by James Horsburgh. It was published by James Horsburgh in 1806. Scale [ca.1:37,820].The image inside the map neatline is georeferenced to the surface of the earth and fit to the Kalianpur 1975 India Zone III projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, cities and other human settlements, fortification, shoreline features (rocks, shoals, anchorage points, ports, inlets, lighthouses, etc.), and more. Relief shown by depth soundings. Includes also profile views and navigational notes.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

Puducherry, India, 1759 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: A plan of Pondicherry in the East Indies, subject to France. It was published by London Magazine in 1759. Scale [ca. 1:14,000]. The image inside the map neatline is georeferenced to the surface of the earth and fit to the Kalianpur 1975 India Zone IV projected coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as roads, drainage, built-up areas and selected buildings, fortification, ground cover, and more. Includes index.This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of originators, ground condition dates, scales, and map purposes.

Indus River Region, India, Pakistan, and Afghanistan, 1816 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Sindetic Hindoostan or the countries occupied by the Sinde or Indus and its branches, by John Cary. It was published by J. Cary June 1, 1816. Scale [ca. 1:7,000,000]. Covers the Indus River region including portions of Northwest India, Pakistan, Afghanistan and Kashmir. The image inside the map neatline is georeferenced to the surface of the earth and fit to a modified 'Asia North Lambert Conformal Conic' projection with a central meridian of 72 degrees East. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, cities and other human settlements, roads, territorial boundaries, shoreline features, and more. Relief shown by hachures. This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection as part of the Open Collections Program at Harvard University project: Islamic Heritage Project. Maps selected for the project represent a range of regions, originators, ground condition dates, scales, and purposes. The Islamic Heritage Project consists of over 100,000 digitized pages from Harvard's collections of Islamic manuscripts and published materials. Supported by Prince Alwaleed Bin Talal and developed in association with the Prince Alwaleed Bin Talal Islamic Studies Program at Harvard University.

Ganges River Region, India and Bangladesh, 1816 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Gangetic Hindoostan or the countries occupied by the Ganges and the branches, by John Cary. It was published by J. Cary in June 1, 1816. Scale [ca. 1:7,000,000]. Covers the Ganges River region, Bangladesh and Northeast India, and portions of China, Nepal, and Bhutan. The image inside the map neatline is georeferenced to the surface of the earth and fit to a modified 'Asia North Lambert Conformal Conic' projection with a central meridian of 84 degrees East projection. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, cities and other human settlements, roads, territorial boundaries, shoreline features, and more. Relief shown by hachures. This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection as part of the Open Collections Program at Harvard University project: Islamic Heritage Project. Maps selected for the project represent a range of regions, originators, ground condition dates, scales, and purposes. The Islamic Heritage Project consists of over 100,000 digitized pages from Harvard's collections of Islamic manuscripts and published materials. Supported by Prince Alwaleed Bin Talal and developed in association with the Prince Alwaleed Bin Talal Islamic Studies Program at Harvard University.

Central and Northern India, 1816 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Central division of Hindoostan, by John Cary. It was published by J. Cary, June 1, 1816. Scale [ca. 1:7,000,000]. Covers central and northern India and portions of Pakistan and Nepal. The image inside the map neatline is georeferenced to the surface of the earth and fit to a modified 'Asia North Lambert Conformal Conic' projection with a central meridian of 78 degrees East. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as drainage, cities and other human settlements, roads, territorial boundaries, shoreline features, and more. Relief shown by hachures. This layer is part of a selection of digitally scanned and georeferenced historic maps from the Harvard Map Collection as part of the Open Collections Program at Harvard University project: Islamic Heritage Project. Maps selected for the project represent a range of regions, originators, ground condition dates, scales, and purposes. The Islamic Heritage Project consists of over 100,000 digitized pages from Harvard's collections of Islamic manuscripts and published materials. Supported by Prince Alwaleed Bin Talal and developed in association with the Prince Alwaleed Bin Talal Islamic Studies Program at Harvard University.

Kolkata, India, City Planning, 1913 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: City of Calcutta, E. P. Richards. It was printed by Jennings & Bewley in 1913. Scale 1:21,120. Covers Kolkata and a portion of Hāora, India. The image inside the map neatline is georeferenced to the surface of the earth and fit to the 'WGS 1984 UTM Zone 45N' coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as residential and industrial zoning districts and redevelopment zones, roads, railroads, drainage, canals, built-up areas and selected buildings, fortification, docks, parks, and more. Includes index, note, legend of class dwellings, and census "map" (i.e., chart). This layer is part of a selection of digitally scanned and georeferenced historic maps from The Harvard Map Collection as part of the Imaging the Urban Environment project. Maps selected for this project represent major urban areas and cities of the world, at various time periods. These maps typically portray both natural and manmade features at a large scale. The selection represents a range of regions, originators, ground condition dates, scales, and purposes.

Kolkata, India, 1852 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Calcutta. It was published under the superintendence of the Society for the Diffusion of Useful Knowledge [by] George Cox, Jan. 1, 1852. Scale [ca. 1:21,500]. Covers Kolkata and a portion of Hāora, India. The image inside the map neatline is georeferenced to the surface of the earth and fit to the 'WGS 1984 UTM Zone 45N' coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as roads, drainage, canals, built-up areas and selected buildings, fortification, parks, ground cover, and more. Includes views and index of selected buildings. This layer is part of a selection of digitally scanned and georeferenced historic maps from The Harvard Map Collection as part of the Imaging the Urban Environment project. Maps selected for this project represent major urban areas and cities of the world, at various time periods. These maps typically portray both natural and manmade features at a large scale. The selection represents a range of regions, originators, ground condition dates, scales, and purposes.

Kolkata, India, 1832 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Map of the city and environs of Calcutta : constructed chiefly from Major Schalch's map and from Captain Prinsep's surveys of the suburbs with the latest improvements and topographic details by J. B. Tassin. It was published by J.B. Tassin in 1832. Scale [ca. 1:21,450]. Covers Kolkata and a portion of Haora, India.The image inside the map neatline is georeferenced to the surface of the earth and fit to the 'WGS 1984 UTM Zone 45N' coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map.This map shows features such as roads, drainage, canals, built-up areas and selected buildings, brick buildings, fortification, ground cover, parks, gardens, cemeteries, rice fields, and more. Includes list of references and legend. This layer is part of a selection of digitally scanned and georeferenced historic maps from The Harvard Map Collection as part of the Imaging the Urban Environment project. Maps selected for this project represent major urban areas and cities of the world, at various time periods. These maps typically portray both natural and manmade features at a large scale. The selection represents a range of regions, originators, ground condition dates, scales, and purposes.

Kolkata, India, Sociological Map, 1910 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: City of Calcutta : sociological map. It was published by Taylor, Garnett, Evans & Co. in 1910. Scale [ca 1:21,120]. Covers Kolkata and a portion of Hāora, India. The image inside the map neatline is georeferenced to the surface of the earth and fit to the 'WGS 1984 UTM Zone 45N' coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as roads, existing and proposed railroads, manufacturing and shipping areas, residential and business areas by ethinicity, drainage, canals, built-up areas and selected buildings, fortification, parks, and more. This layer is part of a selection of digitally scanned and georeferenced historic maps from The Harvard Map Collection as part of the Imaging the Urban Environment project. Maps selected for this project represent major urban areas and cities of the world, at various time periods. These maps typically portray both natural and manmade features at a large scale. The selection represents a range of regions, originators, ground condition dates, scales, and purposes.

Kolkata, India, Roads, 1910 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Urban Calcutta : the existing street and main road system of Calcutta, E.P. Richards, M. Inst., C.E. It was published by Calcutta Improvement Trust in 1910. Scale [1:21,120]. Covers Kolkata, India. The image inside the map neatline is georeferenced to the surface of the earth and fit to the 'WGS 1984 UTM Zone 45N' coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as roads, railroads, drainage, selected buildings, fortification, docks, and more. This layer is part of a selection of digitally scanned and georeferenced historic maps from The Harvard Map Collection as part of the Imaging the Urban Environment project. Maps selected for this project represent major urban areas and cities of the world, at various time periods. These maps typically portray both natural and manmade features at a large scale. The selection represents a range of regions, originators, ground condition dates, scales, and purposes.

Kolkata, India, Traffic Density, 1913 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Traffic intensities, E. P. Richards. It was published by Calcutta Improvement Trust[?] in 1913. Scale [1:10,560]. Covers Kolkata and a portion of Hāora, India. The image inside the map neatline is georeferenced to the surface of the earth and fit to the 'WGS 1984 UTM Zone 45N' coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as roads with traffic density information, railroads, drainage, canals, selected buildings, fortification, docks, parks, and more. Includes note on traffic intensities and legend of vehicles per hour. This layer is part of a selection of digitally scanned and georeferenced historic maps from The Harvard Map Collection as part of the Imaging the Urban Environment project. Maps selected for this project represent major urban areas and cities of the world, at various time periods. These maps typically portray both natural and manmade features at a large scale. The selection represents a range of regions, originators, ground condition dates, scales, and purposes.

Kolkata, India, Street-railroads, 1910 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Route map : Calcutta & Howrah. It was published by Calcutta Tramways Co. in 1910. Scale [1:21,120]. Covers Kolkata and a portion of Hāora, India. The image inside the map neatline is georeferenced to the surface of the earth and fit to the 'WGS 1984 UTM Zone 45N' coordinate system. All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, index maps, legends, or other information associated with the principal map. This map shows features such as roads, railroads, existing and planned tramways, drainage, canals, selected buildings, and more. Includes notes and index of routes. This layer is part of a selection of digitally scanned and georeferenced historic maps from The Harvard Map Collection as part of the Imaging the Urban Environment project. Maps selected for this project represent major urban areas and cities of the world, at various time periods. These maps typically portray both natural and manmade features at a large scale. The selection represents a range of regions, originators, ground condition dates, scales, and purposes.

Multifaceted Role of Heme during Severe Plasmodium falciparum Infections in India

Several immunomodulatory factors are involved in malaria pathogenesis. Among them, heme has been shown to play a role in the pathophysiology of severe malaria in rodents, but its role in human severe malaria remains unclear. Circulating levels of total heme and its main scavenger, hemopexin, along with cytokine/chemokine levels and biological parameters, including hemoglobin and creatinine levels, as well as transaminase activities, were measured in the plasma of 237 Plasmodium falciparum-infected patients living in the state of Odisha, India, where malaria is endemic. All patients were categorized into well-defined groups of mild malaria, cerebral malaria (CM), or severe noncerebral malaria, which included acute renal failure (ARF) and hepatopathy. Our results show a significant increase in total plasma heme levels with malaria severity, especially for CM and malarial ARF. Spearman rank correlation and canonical correlation analyses have shown a correlation between total heme, hemopexin, interleukin-10, tumor necrosis factor alpha, gamma interferon-induced protein 10 (IP-10), and monocyte chemotactic protein 1 (MCP-1) levels. In addition, canonical correlations revealed that heme, along with IP-10, was associated with the CM pathophysiology, whereas both IP-10 and MCP-1 together with heme discriminated ARF. Altogether, our data indicate that heme, in association with cytokines and chemokines, is involved in the pathophysiology of both CM and ARF but through different mechanisms.