Peaks, passes and glaciers. A series of excursions by members of the Alpine Club. [Series 1]-3 ...

[Ser. 1] edited by John Ball; ser.2 by Edward Shirley Kennedy; ser.3, by A.E. Field and Sydney Spencer.

The peaks of medical history; an outline of the evolution of medicine for the use of medical students and practitioners,

"Bibliographical notes": p. 95-100

Mountaineering in Colorado : the peaks about Estes Park /

Mode of access: Internet.

Mountain peaks of the Bible,

Mode of access: Internet.

Short-term peaks in glucose promote renal fibrogenesis independently of total glucose exposure

Postprandial hyperglycemia is implicated as a risk factor predisposing to vascular complications. This study was designed to assess recurrent short-term increases in glucose on markers of renal fibrogenesis. Human renal cortical fibroblasts were exposed to fluctuating short-term (2 h) increases to 15 mM D-glucose, three times a day over 72 h, on a background of 5 mM D-glucose. To determine whether observed changes were due to fluctuating osmolality, identical experiments were undertaken with cells exposed to L-glucose. Parallel experiments were performed in cells exposed to 5 mM D-glucose and constant exposure to either 15 or 7.5 mM D-glucose. Fluctuating D-glucose increased extracellular matrix, as measured by proline incorporation ( P < 0.05), collagen IV ( P < 0.005), and fibronectin production ( P < 0.001), in association with increased tissue inhibitor of matrix metalloproteinase (MMP) ( P < 0.05). Sustained exposure to 15 mM D-glucose increased fibronectin ( P < 0.001), in association with increased MMP-2 ( P = 0.01) and MMP-9 activity ( P < 0.05), suggestive of a protective effect on collagen matrix accumulation. Transforming growth factor-beta(1) (TGF-beta(1)) mRNA was increased after short-term (90 min) exposure to 15 mM glucose (P < 0.05) and after 24-h exposure to 7.5 mM ? ( P < 0.05). Normalization of TGF-beta(1) secretion occurred within 48 h of constant exposure to an elevated glucose. Fluctuating L-glucose also induced TGF-beta(1) mRNA and a profibrotic profile, however, to a lesser extent than observed with exposure to fluctuating D-glucose. The results suggest that exposure to fluctuating glucose concentrations increases renal interstitial fibrosis compared with stable elevations in D-glucose. The effects are, in part, due to the inherent osmotic changes.

Tunnelling density of states at Coulomb-blockade peaks

We calculate the tunnelling density of states (TDoS) for a quantum dot in the Coulomb-blockade regime, using a functional integral representation with allowing correctly for the charge quantisation. We show that in addition to the well-known gap in the TDoS in the Coulomb-blockade valleys, there is a suppression of the TDoS at the peaks. We show that such a suppression is necessary in order to get the correct result for the peak of the differential conductance through an almost close quantum dot.

Telephones, Voice Recorders, Microphones, Phonographs: A Media Archaeology of Sonic Technologies in Twin Peaks

This article argues that sonic technologies, such as telephones, voice recorders and phonographs, alongside more (audio)visual ones such as flickering fluorescent lights, videos, and the television sets are crucial to the world of Twin Peaks, and constitute this world as both a communications network with portals to the unknown, and an accumulation of recordings of ghosted voices and entities, perhaps finding its ultimate expression in the backwards reprocessed speech in the Black Lodge. This lodge can be understood as a space in which there are nothing but recordings, albeit now on a cosmic, spiritual and demonic level. Using a media archaeological approach to these devices in the series, this paper will argue that they were already operating by a media archaeological logic, generating the world of Twin Peaks as a haunted archive of sonic and other mediations.

David Bowie, brinquedos adultos e outras dimensões estranhas do universo de Twin Peaks

The article is based fundamentally on the authors' participation in the International Conference “I’ll See You Again in 25 Years: The return of Twin Peaks and generations of cult TV”, held on 21 and 22 May 2015, at the School of Arts and Media, at the University of Salford in England. Starting from there, it makes an irregular discussion of issues and working angles around the television series launched in 1990, a work by David Lynch and Mark Frost. Some issues gain particular attention: 1) the relations of the series to the album Outside (1995) by David Bowie; 2) the population of adult toys related to the series, as derivative products, driven by fans in their most playful exercises of affection and remembrance. Despite the article’s intentionally adopted tone of an “academic report”, it can evoke rich theoretical questions in a field of objects that are in a complex upgrade process and have to be subsequently treated according to more regular methodological procedures, seeking further theoretical and epistemological clarifications

A Simple Model Describes Development of Early Peaks in Oomycete Zoospore Inoculum Detected in Southern UK Outdoors Horticultural Reservoirs

The numbers of water-borne oomycete propagules in outdoor reservoirs used in horticultural nurseries within the UK are investigated in this study. Water samples were recovered from 11 different horticultural nurseries in the southern UK during Jan-May in two ‘cool’ years (2010.and 2013; winter temperatures 2.0 and 0.4oC below UK Met Office 30 year winter average respectively) and two ‘warm’ years (2008 and 2012; winter temperatures 1.2 and 0.9oC above UK Met Office 30 year winter average respectively). Samples were analysed for total number of oomycete colony forming units (CFU), predominantly members of the families Saprolegniaceae and Pythiaceae, and these were combined to give monthly mean counts. The numbers of CFU were investigated with respect to prevailing climate in the region: mean monthly air temperatures calculated by using daily observations from the nearest climatological station. The investigations show that the number of CFU during spring can be explained by a linear first-order equation and a statistically significant r2 value of 0.66 with the simple relationship: [CFU] = a(T-Tb )-b, where a is the rate of inoculum development with temperature T, and b is the baseload population at temperatures below Tb. Despite the majority of oomycete CFU detected being non-phytopathogenic members of the Saprolegniaceae, total oomycete CFU counts are still of considerable value as indicators of irrigation water treatment efficacy and cleanliness of storage tanks. The presence/absence of Pythium spp. was also determined for all samples tested, and Pythium CFU were found to be present in the majority, the exceptions all being particularly cold months (January and February 2010 and January 2008). A simple scenario study (+2 deg C) suggests that abundance of water-borne oomycetes during spring could be affected by increased temperatures due to climate change.

The ‘peaks and troughs’ of societal violence: Revisiting the actions of Turkish and Kurdish shopkeepers during the 2011 London riots

This article examines an instance of contained violence during the 2011 riots in London, when Turkish and Kurdish ‘shopkeepers’ in Dalston, East London prevented rioters from entering the area. Introducing a ‘peaks’ and ‘troughs’ approach to the sociological study of violence, the article argues that we need to look at the troughs of non-violence in order to understand the peaks of violence and vice-versa. Based on a small-scale empirical study, this article also shows that contrary to the dominant representation of social actors playing fixed roles during social unrest, we found shifting positions and blurred boundaries in the drama of the 2011 riots. The paper demonstrates that the instance of contained violence in Dalston was informed by three types of reverberations. Firstly, we identified anticipatory reverberations, as the shopkeepers were aware of concurrent events elsewhere in London and, as a result, anticipated rioting in Dalston. Secondly, we saw experiential reverberations, as they used their own experience of unrest in Turkey to inform their behaviour. Finally, the representation of the action of the shopkeepers in traditional and social media may have contributed to the containment of violence elsewhere in England, suggesting representational reverberations.

May the Giant Be With You: Twin Peaks Season Two, Episode One and the Television Auteur

The premiere of Season Two of Twin Peaks garnered some of the highest ratings of the series, with celebrated filmmaker and co-creator David Lynch stepping back into the director’s chair. Yet, within this episode many traditional television conventions are flouted, and in response the following week the ratings dropped dramatically. From its slow-paced opening scenes in which an old man admonishes the wounded, bleeding protagonist to drink his warm milk before it gets cold, followed by a vision of a giant speaking in riddles, this episode not only tested its audience’s patience but also seemed to set out to deliberately confuse them. In this essay I will explore how this episode is an example of auteur television, an episode in which the director expresses a consistency of style and theme that is similar to their other work, as well as examine how Lynch’s approach to televisual aesthetics has influenced the way that contemporary film directors have crossed over into the television medium. However, when taking into account the differences in the two media of film and television notions of authorship, with regards to the position of the director, become complicated, especially when considering contemporary television and the rise of the showrunner as key creative force. Even when looking back at Lynch’s contribution to Twin Peaks it becomes clear that the series was deeply collaborative, with Lynch absent during parts of the filming. Yet, when examining the extensive material that has been written about Twin Peaks there is still a continuing tendency to place Lynch as the sole author. The placement of Lynch as author can be argued in relation to the episodes he directed (as will be explored below in relation to the first episode of Season Two), but cannot be attributed to him alone when considering the series as a whole. Finally, I will discuss how the figure of the television auteur has become a central element of television reception rather than production, an integral part of a viewer’s search for narrative meaning in a medium where complexity and mystery are now expected and enjoyed. Just as fans scrambled to uncover the many secrets and mysteries of Twin Peaks by looking to Lynch’s other works for answers, a similar process is experienced by fans of television shows existing today.

Fueling growth when oil peaks: directed technological change and the limits to efficiency

While fossil energy dependency has declined and energy supply has grown in the postwar world economy, future resource scarcity could cast its shadow on world economic growth soon if energy markets are forward looking. We develop an endogenous growth model that reconciles the current aggregate trends in energy use and productivity growth with the intertemporal dynamics of forward looking resource markets. Combining scarcity-rent driven energy supply (in the spirit of Hotelling) with profit-driven Directed Technical Change (in the spirit of Romer/Acemoglu), we generate transitional dynamics that can be qualitatively calibrated to current trends. The long-run properties of the model are studied to examine whether current trends are sustainable. We highlight the role of extraction costs in mining.

Aplicabilidade do modelo twin peaks á regulaçao financeira em Portugal

A supervisão de um mundo financeiro muito diversificado e complexo tornou-se uma prioridade e um assunto em destaque desde o despoletar da crise financeira em 2007. O relatório de Larosiere(2009), que surge a pedido da União Europeia, defende que o Twin Peaks é o modelo que melhor resposta pode dar ao mundo financeiro globalizado, complexo e interligado. Este relatório esteve mesmo na base da nova estrutura da supervisão da União Europeia. Por outro lado, acabou por motivar as alterações nos Estados-membros que já estavam em curso, como é o caso do Reino Unido que terminou, em 2013, o processo de adoção de um modelo de supervisão por objetivos. a Holanda já desde 2007 que odotou o Twin Peaks e é a garnde referencia europeia da aplicabilidade do modelo. Protugal procura acompanhar os requesitos da supervisão da Uniao Europeia, ainda com mais atenção, após os escândalos de fraude no setor bancário Portugues. Portugal, que mantem ainda hoje um Modelo Setorial já com alguns ajustamentos, lançou uma consulta publica sobre a proposta de alteração do atual modelo para o Twin Peaks. O estado de emergência financeira em que o pais entrou adiou a discussão sobre esse tema, nunca se concretizou a sua adoção até á data. O presente trabalho visa analisr, por um lado, a efetiva aplicabilidade deste Modelo no sistema financeiro português, extraindo as alterações que implicaria e as vantagens e desvantagens da sai implementação, utilizando como base comparativa os modelos implementados na Holanda e, mais recentemente, no Reino Unido. O modelo Twin Peaks proposto tem grandes semelhancas com o Holandes,criando atraves do Conselho Nacional de Supervisores Financeiros o elo de ligacao entre os restantes agentes de forma assegurar o sucesso na definicao dos objetivos e interligados (fator critico para o sucesso do modelo).Efetivamente,os fatores que justificaram a alteracao do Modelo na Holanda e Reino Unido estao presents,na sua maioria,na economia portuguesa. Na literature, encontramos diversos fatores que validam a aplicacao do Modelo Twin Peaks a regulacao financeira portuguesa, nao obstante levantaram/se ainda reservas quanto a validadedacapacidade de interligacao de uma Europa com um modelo cada vez mais sectorial com os estados membros protocolados ao Twin peaks e a capacidade de definicao de objetivos e amplitude de atuacao de cada agente nacional.