Conferenza sul temporal governo degli ecclesiastici.

Appendix [with title reading]: Discorso apologetico sulla origina della temporale domniazione dei papi, 128 pages at end.

Il Paradiso perduto /

"Osservazioni critiche del signore Addison sul Paradiso perduto": p. [xxix]-lxvi.

Le paradise perduto

Mode of access: Internet.

Il paradiso perduto.

The title-page is engraved.

Il paradiso perduto.

Mode of access: Internet.

Comentarii della rivoluzione francese dalla congregazione degli stati generali fino alla morte di Napoleone Bonaparte.

Mode of access: Internet.

A Semantic-Oriented Architecture of a Functional Module for Personalized and Adaptive Access to the Knowledge in a Multimedia Digital Library

This article presents the principal results of the doctoral thesis “Semantic-oriented Architecture and Models for Personalized and Adaptive Access to the Knowledge in Multimedia Digital Library” by Desislava Ivanova Paneva-Marinova (Institute of Mathematics and Informatics), successfully defended before the Specialised Academic Council for Informatics and Mathematical Modelling on 27 October, 2008.

Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)

Peer reviewed

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus

BACKGROUND: Multiple recent genome-wide association studies (GWAS) have identified a single nucleotide polymorphism (SNP), rs10771399, at 12p11 that is associated with breast cancer risk. METHOD: We performed a fine-scale mapping study of a 700 kb region including 441 genotyped and more than 1300 imputed genetic variants in 48,155 cases and 43,612 controls of European descent, 6269 cases and 6624 controls of East Asian descent and 1116 cases and 932 controls of African descent in the Breast Cancer Association Consortium (BCAC; http://bcac.ccge.medschl.cam.ac.uk/ ), and in 15,252 BRCA1 mutation carriers in the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA). Stepwise regression analyses were performed to identify independent association signals. Data from the Encyclopedia of DNA Elements project (ENCODE) and the Cancer Genome Atlas (TCGA) were used for functional annotation. RESULTS: Analysis of data from European descendants found evidence for four independent association signals at 12p11, represented by rs7297051 (odds ratio (OR) = 1.09, 95 % confidence interval (CI) = 1.06-1.12; P = 3 × 10(-9)), rs805510 (OR = 1.08, 95 % CI = 1.04-1.12, P = 2 × 10(-5)), and rs1871152 (OR = 1.04, 95 % CI = 1.02-1.06; P = 2 × 10(-4)) identified in the general populations, and rs113824616 (P = 7 × 10(-5)) identified in the meta-analysis of BCAC ER-negative cases and BRCA1 mutation carriers. SNPs rs7297051, rs805510 and rs113824616 were also associated with breast cancer risk at P < 0.05 in East Asians, but none of the associations were statistically significant in African descendants. Multiple candidate functional variants are located in putative enhancer sequences. Chromatin interaction data suggested that PTHLH was the likely target gene of these enhancers. Of the six variants with the strongest evidence of potential functionality, rs11049453 was statistically significantly associated with the expression of PTHLH and its nearby gene CCDC91 at P < 0.05. CONCLUSION: This study identified four independent association signals at 12p11 and revealed potentially functional variants, providing additional insights into the underlying biological mechanism(s) for the association observed between variants at 12p11 and breast cancer risk

Smart Cities @ DIITET

La presentazione oltre a illustrare le attività progettuali del Dipartimento di Ingegneria, ICT e Tecnologie per l'Energia e i Trasporti (DIITET) del Consiglio Nazionale delle Ricerche (CNR) nell'ambito delle Smart Cities, spiega che cos'è una città intelligente/sostenibile, i livelli su cui opera, perchè è importante. Si evidenziano tre esempi progettuali concreti testati anche con i cittadini su tre città italiante: Siracusa, Pisa e Bologna.

Sinergia, strategie per favorire nuovi modelli di business

La presente guida alle attività di ricerca del Dipartimento di Ingegneria, ICT e Tecnologie per l’Energia e Trasporti (DIITET) del Consiglio Nazionale delle Ricerche (CNR), vuole fornire un agile e sintetico strumento di conoscenza al quotidiano lavoro svolto dal personale che opera presso gli Istituti afferenti al dipartimento stesso e di quelli appartenenti ad altri dipartimenti che condividono con il DIITET ambiti di ricerca interdisciplinari. I dati attualmente disponibili saranno riferiti a variabili di tre tipi: 1) aree progettuali e, al loro interno, tematiche di ricerca in cui sono attivi gli istituti CNR; 2) personale operante in tali istituti; 3) prodotti di proprietà intellettuale e pubblicazioni degli istituti stessi.

Sistema electrónico de protección contra las heladas que afectan los cultivos de papa

103 p.

Energy consumption of parallel algorithms for solving linear systems on HPC architecture

Modern High-Performance Computing HPC systems are gradually increasing in size and complexity due to the correspondent demand of larger simulations requiring more complicated tasks and higher accuracy. However, as side effects of the Dennard’s scaling approaching its ultimate power limit, the efficiency of software plays also an important role in increasing the overall performance of a computation. Tools to measure application performance in these increasingly complex environments provide insights into the intricate ways in which software and hardware interact. The monitoring of the power consumption in order to save energy is possible through processors interfaces like Intel Running Average Power Limit RAPL. Given the low level of these interfaces, they are often paired with an application-level tool like Performance Application Programming Interface PAPI. Since several problems in many heterogeneous fields can be represented as a complex linear system, an optimized and scalable linear system solver algorithm can decrease significantly the time spent to compute its resolution. One of the most widely used algorithms deployed for the resolution of large simulation is the Gaussian Elimination, which has its most popular implementation for HPC systems in the Scalable Linear Algebra PACKage ScaLAPACK library. However, another relevant algorithm, which is increasing in popularity in the academic field, is the Inhibition Method. This thesis compares the energy consumption of the Inhibition Method and Gaussian Elimination from ScaLAPACK to profile their execution during the resolution of linear systems above the HPC architecture offered by CINECA. Moreover, it also collates the energy and power values for different ranks, nodes, and sockets configurations. The monitoring tools employed to track the energy consumption of these algorithms are PAPI and RAPL, that will be integrated with the parallel execution of the algorithms managed with the Message Passing Interface MPI.