As Leprolinas "Souza-Araujo" e a sua rápida acção terapêutica nos males perfurantes plantares lepróticos

The A. remembers the history of his lepra-culture and the method he uses to prepare with it the antigen called Leprolin Souza-Araujo, giving photographic illustrations upon the subject. The A. says that the results published about the general action of his Leprolin in leprosy must be revised or rectificated. But he says that the rapid action of his antigen upon perforant ulcers in lepers is consecrated by a large experience. He cured, in relatively short time, perforant ulcers in five lepers. Dr. CASSIANO, from Baurú leper Colony (S. Paulo) treated 21 such cases. The median time of treatment was 23 days and the median dosage of Leprolin injected in each patient was 7.7 cm3. All lesions were cured. After 18 months observation three cases relapsed and 18 (or 85.7%) remained cured. Dr. CALDEIRA, Director of padre DAMIEN Leper Colony (Ubá, Minas Gerais) treated regularly with Leprolin 50 cases of severe perforant ulcers and obtained cure in 46 (or 92%). ina special meeting held in Minas Gerais nineteen leprologists examined the cases of Dr. CALDEIRA and considered the results he have obtained as "magnifico", in the sense as "unic". This experiment is being continued in various brazilian leper colonies and the Author offers, graciously, his antigen to be tried also in foreing countries.

A Leprolina "Souza-Araujo" no tratamento da lepra

The A. summarizes clinical records of four lepers treated with Leprolin “Souza-Araujo”, as follow: ist – Male, 28 years old, lepromatous case, treated during about 3 years, who received 80 injections of the antigen, being 52 by vene, 18 by muscle and 10 intradermally. Total about 100 cm³. Results: Absence of clinical signs, routine examinations negative for acidfast bacilli. Histopathology: from lepromatous became incaracteristic, with a few bacilli. Mitsuda test from negative became positive. 2nd – Male, 33 ys. old, lepromatous case. From September 1944 to February 1948 received 110 intravenous injections (57 cm³) and 10 cm³ perineurally to control neurites. His Mitsuda test was negative in 1944 and in 1945 became positive and remained so until 1948 (4 times controlled). Since Sept. 1946 became bacillus negative in his mucous, ear lobe and lymph nodes. Out of his lepromatous symptoms remained only mild atrophy of his hands. 3rd- Male, 30 ys. old, lepromatous case, treated since 1944. From 1946 to Feb. 1948 received 80 intravenous injections (high dosage: from 2 to 5 cm³), total 310 cm³ and 140 cm³ intramuscularly. His Mitsuda test was negative in 1943; became positive (from 1945 till 1948) after Leprolin treatment. Bacilloscopy became negative even in sections. Histopathology: the lesions from lepromatous changed to tuberculoid. 4th – Male, 17 years old, lepromatous case, received, from Dec. 1944 to Feb. 1948 only 88 intravenous injections of small doses of Leprolin (0,1 to 1,0 cm³). His Mitsuda remained negative from 1944 to 1946 and in 1947 became positive. Routine examinations negative for bacilli. Histopathology: the lepromataus lesions regressed to incaracteristic, without bacillus.

Contribuição à terapêutica do mal perfurante plantar: tratamento pela leprolina "Souza-Araujo" em injeções intra-ulcerosas

The writer, as medical director of Father Damien Leper Colony (Ubá, Minas Gerais, Brasil), treated 50 cases of perforating ulcers, from 2 to 40 years of duration, using the antigens prepared with acid-fast bacilli cultures obtained from leprous material by Dr. H. C. de Souza-Araujo. Dosage from 0,12 to 39,35 cm3, injected inside the ulcers, intramuscularly, every 2 to 4 days, accordingly to the patient reaction some of them presenting fever until 41° Centigrade. The result was cicatrization of the ulcers in 92% (46 out of 50) of the patients. The author concluded that the majority of his patients tolerate perfectly the medicine and that its efect was very eficient.

Sport and international relations (1913-1939): the 1936 Popular Olympiad

This document includes the results of the research undertaken by the authors on the attempts to organise a Popular Olympiad in Barcelona in 1936.

Ethiques de la description: naissance de l'imagination typologique en France, dans le roman et la sociologie (1820-1860)

Résumé: Ce travail d'histoire comparée de la littérature et de la sociologie s'interroge sur l'émergence de la notion de type dans les pratiques de description du monde social au cours des années 1820-1860. A partir de l'analyse des opérations de schématisation engagées par Honoré Balzac dans La Comédie humaine et par Frédéric Le Play dans Les Ouvriers européens, soit deux oeuvres que tout semble éloigner du point de vue de leurs ambitions, de leur forme, et de la trajectoire de leur auteur, mais qui toutes deux placent cependant la typification au centre de leur dispositif, il s'est agi de produire une histoire de l'imagination typologique, et des ontologies, sociales ou non, qui lui furent associées. Aussi le corpus intègre-t-il des textes d'histoire naturelle, de sciences médicales, d'histoire, de chimie, de géologie, de métallurgie, et, bien évidemment, les genres du roman sentimental, du roman historique et de la littérature panoramique, ainsi que les enquêtes ouvrières et la statistique. Abstract: This work offers a compared history of literature and sociology in France between 1820 and 1860. During that period, the notion of type appears in the literary and sociological descriptions of social reality, and becomes more and more central in the apprehension of the differenciations among classes, communities or groups. Based on the analysis of Honoré Balzac's La Comédie humaine and Frédéric Le Play's Les Ouvriers européens, this study shows that these two series of novels and of workers' monographies put typification at the center of their descriptive ambition. More broadly, it proposes a history of the uses of a typological imagination and of the ontologies, above all social, that were underlying them. That is why the texts also taken into account in this study ranges from natural history, medical sciences, history, chemistry geology and metallurgy, to the sentimental novel, the historical novel and the panoramic literature, as well as social inquiries and statistics.

Sobre la Girona Constitucional (1820-1823)

Sobre la Girona Constitucional del trienni 1820-1823, en base la documentació existent a l'Arxiu Municipal i a l'Arxiu Diocesà

Syphacia sp. (Nematoda: Oxyuridae) in coprolites of Kerodon rupestris Wied, 1820 (Rodentia: Caviidae) from 5,300 years BP in northeastern Brazil

We present the results of paleoparasitological analyses in coprolites of Kerodon rupestris, rodent endemic to rocky areas of Brazil's semiarid region. The coprolites were collected from excavations at the archaeological site of Toca dos Coqueiros, in the National Park of Serra da Capivara, southeastern of state of Piauí. Syphacia sp. (Nematoda: Oxyuridae) eggs were identified in coprolites dated at 5,300 ± 50 years before present. This is the first record of the genus Syphacia in rodent coprolites in the Americas.