Multippeli myelooma : koiran harvinainen syöpätauti

Summary: Multiple myeloma - an uncommon canine neoplastic disease

Tamman ternimaidon laadun määritys ominaispainon avulla

Summary: Determination of mare colostrum quality by measuring specific gravity

Counter-ion effect on surfactant-DNA gel particles as controlled DNA delivery systems

The ability to entrap drugs within vehicles and subsequently release them has led to new treatments for a number of diseases. Based on an associative phase separation and interfacial diffusion approach, we developed a way to prepare DNA gel particles without adding any kind of cross-linker or organic solvent. Among the various agents studied, cationic surfactants offered particularly efficient control for encapsulation and DNA release from these DNA gel particles. The driving force for this strong association is the electrostatic interaction between the two components, as induced by the entropic increase due to the release of the respective counter-ions. However, little is known about the influence of the respective counter-ions on this surfactant-DNA interaction. Here we examined the effect of different counter-ions on the formation and properties of the DNA gel particles by mixing DNA (either single- (ssDNA) or double-stranded (dsDNA)) with the single chain surfactant dodecyltrimethylammonium (DTA). In particular, we used as counter-ions of this surfactant the hydrogen sulfate and trifluoromethane sulfonate anions and the two halides, chloride and bromide. Effects on the morphology of the particles obtained, the encapsulation of DNA and its release, as well as the haemocompatibility of these particles, are presented, using the counter-ion structure and the DNA conformation as controlling parameters. Analysis of the data indicates that the degree of counter-ion dissociation from the surfactant micelles and the polar/hydrophobic character of the counter-ion are important parameters in the final properties of the particles. The stronger interaction with amphiphiles for ssDNA than for dsDNA suggests the important role of hydrophobic interactions in DNA.

Glukokortikoidien käyttö naudalla : kirjallisuuskatsaus

Summary: Glucocorticoid therapy in bovine medicine - a review

Tiedekunta julkisti verkkojulkaisusarjan

Sisältää Satu Pyörälän esityksen julkaisuja-sarjan ensimmäisestä julkaisusta: Hirvonen's thesis on acute phase response in dairy cattle

Maidontuotantomme haasteena utaretulehdus ja tuotannon tehostaminen

Lyhennelmä professori Satu Pyörälän esitelmästä "Suomalainen maito uuden vuosituhannen alussa - mahdollisuuksia ja haasteita"

Etelä-Pohjanmaan lypsykarjojen terveydenhuoltoprojektin tuloksia vuosilta 1998-1999

Summary: The results of a health management project in dairy cattle farms in South Pohjanmaa, Finland during 1998-1999

Juoksutusmahan dilaation ja dislokaation kirurginen hoito naudalla : kirjallisuuskatsaus ja kaksi tapausselostusta dislokaation uusimisesta leikkauksen jälkeen

Summary: Surgical correction of abomasal displacement in dairy cattle : a literature review and two case reports of relapses after omentopexia

Naudan kokkidioosi : kirjallisuuskatsaus ja tutkimus kokkidien esiintymisestä suomalaisissa vasikoissa

Summary: Bovine coccidiosis - a literature review and study of prevalence of coccidiosis in Finnish calves

Raudan imeytyminen ja paikallinen kudosärsytys porsailla lihaksensisäisen tai nahanalaisen rautadekstraani-injektion jälkeen

Summary: Absorption of iron and local tissue irritation after intramuscular or subcutaneous administration of an iron-dextran preparation to piglets