Metadifferentiation of iris nevi after iridectomy: a clinicopathological small case series

Abstract Purpose Iridectomy of suspicious pigmented tumors provides the presumed advantage of both a histopathological diagnosis and treatment of the lesion. We present 2 patients that developed an iris melanoma with extrascleral extension at the site of their iridectomy of a histopathologically proven nevus, 46 and 2.5 years later. Methods Retrospective, clinicopathological small case series of 2 patients. Results Two patients underwent iridectomy for a suspicious tumor, the first in 1963 and the second in 2006. Pathological diagnosis was a benign and a borderline nevus respectively. In 2009, both patients presented with a recurrent melanocytic iridociliary tumor with an extrascleral extension adjacent to the surgical scar. Pathological examination confirmed melanoma. Consequently, the two patients underwent proton beam therapy of the whole anterior segment, with limbus deposition and reposition. Conclusion Iridectomy of a histopathologically proven nevus doesn't exclude the possibility of a metadifferentiation of remaining nevus cells into melanoma, even after 46 years. Additionally, treatment in case of a recurrence is more complicated than a primary radiotherapy of the unbiopsied iris tumor, with clinical proof of growth, would have been.

L'educació moral a través de la literatura. El punt de vista d'Iris Murdoch

L'egoisme és, en paraules de Murdoch, l'enemic més gran de la moralitat. L'art es presenta com una de les possibilitats de treure el jo de si mateix perquè prengui consciència del món. La finalitat d'aquest article és posar de manifest la importància i també l'interès de la literatura com a vehicle de reflexió i de presa de consciència de la realitat en la que es mou l'ésser humà tal com ens ho presenta Iris Murdoch. Sota aquest punt de vista la literatura posseeix una clara funció educativa moral.

Iris-Polka & Amazonen-Polka von Pergler für Piano-Forte

Simananniemen käsikirjoituskokoelma.

Les arènes de la normalisation internationale à l'épreuve de la participation de la société civile : résultats du projet INTERNORM

Les normes internationales occupent une place de plus en plus importante dans la gouvernance des marchés et ont souvent une incidence directe sur la santé, la sécurité et l'environnement. Mais la société civile est le plus souvent absente des procédures de normalisation. Il est recommandé de favoriser la participation des acteurs de la société civile dans la normalisation par une mise en forme des travaux de normalisation à même d'encourager leur mobilisation selon les thèmes et enjeux abordés et par l'organisation de l'expertise plurielle requise pour une participation effective à même de leur conférer une certaine influence.

Iris, Op. 85 no. 3

Soitinnus: Piano.

Kiivasta taistoa Iris Uurron tuotannossa

Kirjallisuusarvostelu

Efecto del pH y de la adición de fosfatos de sodio sobre las propiedades de gelificación y emulsión de surimi de trucha arco-iris (Oncorhynchus mykiss)

Para la elaboración de surimi se han empleado distintas técnicas, sin embargo, es indispensable mantener la funcionalidad de las proteínas musculares durante su extracción, ya que son afectadas principalmente por el pH. La incorporación de fosfatos en productos cárnicos afecta el pH, teniendo como consecuencia una mejora en la capacidad de retención de agua de las proteínas musculares, alterando la funcionalidad de estos productos. Se utilizó la metodología de superficie de respuesta para determinar el efecto de cinco niveles de pH y cinco concentraciones de una mezcla de fosfatos de sodio comercial sobre la funcionalidad de surimi de trucha arco-iris, evaluada por su capacidad de emulsión y trabajo de emulsión, fuerza de gel y trabajo de penetración de geles de surimi. Los resultados obtenidos indican que el incremento en la concentración de fosfatos de sodio mejoró la funcionalidad del surimi y a pH alcalino las propiedades de emulsión mejoraron, pero se afectaron negativamente las propiedades de gelificación.

Photograph of Richard, Iris and Albert Sloman [n.d.]

An undated photograph of Richard, Iris and Albert Sloman taken outside what is believed to be a holiday cabin in Parry Sound, Ontario. This photograph was in the possession of the Rick Bell family, of St. Catharines.

Richard Nelson Bell - Iris Sloman Wedding Day Photo, 1939

A black and white photograph taken in 1939 on the occasion of the marriage of Richard Nelson Bell to Iris Sloman. Pictured in the photograph, from left to right, are: Bert Sloman; Richard Nelson Bell; Iris Sloman Bell; and Helen Beatty Sloman. This photograph was in the possession of Rick Bell, the son of Richard Nelson and Iris Bell. The Bell - Sloman family descends from former Black slaves from the United States.Bert Sloman (Albert Edward Sloman) passed away in 1986 at Kitchener-Waterloo, Ontario. His wife Vera Matilda Sloman passed away January 4, 2011 at Cambridge Memorial Hospital. They had a son, Ron Sloman.

Albert, Josie and Iris Sloman in the Vegetable Garden [ n.d.]

This undated black and white family snapshot shows Albert and Josie Sloman (at left) with their daughter, Iris Sloman Bell (third from left) and an unidentified woman in the vegetable garden. The location of the garden is not clear, although it could be St. Catharines or London, Ontario. This photograph was in the possession of Rick Bell, of St. Catharines, whose mother was Iris Sloman Bell. The Sloman - Bell family ancestry includes former Black slaves from the United States who settled in Canada.

Iris Sloman with unidentified woman and sister Helen Sloman [n.d.]

Iris Sloman, at left, with her sister, Helen, far right, and an unidentified woman on the beach in this undated photo. The location could possibly be Port Dalhousie or Parry Sound. This photo was among the family memorabilia retrieved by Rick Bell from his mother's attic in St. Catharines in the 1980s. The Bell - Sloman family descends from former African American slaves who settled in the London and St. Catharines areas.