990 resultados para Hemans, Mrs., 1793-1835


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With: Some notices of the character of Mrs. Sarah Parkman. [S.l. : s.n., 1835?]

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Checklist Amer. imprints

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Mode of access: Internet.

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Inaugural sermon. By J.W. Adams.--Inaugural charge. By Eliakim Phelps.--Inaugural address. By Samuel H. Cox.

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Vol. 2 pt. 3 has special title: Aussergewöhnliches Heft des Briefs des Hans-Jörgels von Gumpoldskirchen ... enthaltend eine ausführliche Beschreibung der Feierlichkeiten und den dabei vorkommen[d]en Ceremonien bei der glorreichen Erhuldigung unseres allergnädigsten Kaisers Ferdinand I am 14ten Juny 1835.

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Mode of access: Internet.

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Ethyl-eicosapentaenoic acid (E-EPA) is an omega-3 fatty acid that has been used in a range of neuropsychiatric conditions with some benefits. However, its mechanism of action is unknown. Here, we investigate its effects on in vivo brain metabolism in first-episode psychosis (FEP). Proton magnetic resonance spectroscopy at 3 T was performed in the temporal lobes of 24 FEP patients before and after 12 weeks of treatment in the context of a larger double-blind, placebo-controlled E-EPA augmentation study. Treatment group effects for glutathione (F1,12=6.1, p=0.03), and a hemisphere-by-group interaction for glutamine/glutamate (F1,20=4.4, p=0.049) were found. Glutathione increased bilaterally and glutamate/glutamine increased in the left hemisphere following E-EPA administration. Improvement in negative symptoms correlated with metabolic brain changes, particularly glutathione (r=-0.57). These results suggest that E-EPA augmentation alters glutathione availability and modulates the glutamine/glutamate cycle in early psychosis, with some of the metabolic brain changes being correlated with negative symptom improvement. Larger confirmatory studies of these postulated metabolic brain effects of E-EPA are warranted.