Effect of light-curing units on push-out fiber post bond strength in root canal dentin

The purpose of this study was to evaluate the effectiveness of different light-curing units on the bond strength (push-out) of glass fiber posts in the different thirds of the root (cervical, middle and apical) with different adhesive luting resin systems (dual-cure total-etch; dual-cured and self-etch bonding system; and dual-cure self-adhesive cements), Disks of the samples (n = 144) were used, with approximately 1 mm of thickness of 48 bovine roots restored with glass fiber posts, that were luted with resin cements photo-activated by halogen LCU (QTH, Optilux 501) and blue LED (Ultraled), with power densities of 600 and 550 mW/cm(2), respectively. A universal testing machine (MTS 810 Material Test System) was used with a 1 mm diameter steel rod at cross-head speed of 0.5 mm/min until post extrusion, with load cell of 50 kg, for evaluation of the push-out strength in the different thirds of each sample. The push-out strength values in kgf were converted to MPa and analyzed through Analysis of Variance and Tukey`s test, at significance level of 5%. The results showed that there were no statistical differences between the QTH and LED LCUs. The self-adhesive resin cement had lower values of retention. The total-etch and self-adhesive system resin cements seem to be a possible alternative for glass fiber posts cementation into the radicular canal and the LED LCU can be applied as an alternative to halogen light on photo-activation of dual-cured resin cements.

Dynamic softening of ferrite during large strain warm deformation of a plain-carbon steel

The evolution of dynamic ferrite softening in a plain-carbon steel was investigated by torsion tests during warm deformation at 810 °C, in the two-phase (ferrite + austenite) region, and strain rate of 0.1 s−1 with different strains up to 50. The warm flow behaviour and ferrite microstructural parameters, such as grain size, misorientation angle across ferrite/ferrite boundaries, and the fraction of high-angle and low-angle grain/subgrain boundaries were quantified using electron back scatter diffraction. The results show that with increasing strain up to not, vert, similar2, the ferrite grain size and fraction of high-angle boundaries rapidly decrease and the fraction of low-angle boundaries increases. However, these parameters remain approximately unchanged with increasing strain from not, vert, similar2 to 50. The dynamic softening mechanism observed during large strain ferritic deformation is explained by dynamic recovery and continuous dynamic recrystallization.

In-hospital falls and fall-related injuries: a protocol for a cost of fall study

Background:
In-hospital falls are common and pose significant economic burden on the healthcare system. To date, few studies have quantified the additional cost of hospitalisation associated with an in-hospital fall or fall-related injury. The aim of this study is to determine  the additional length of stay and hospitalisation costs associated with in-hospital falls and fall-related injuries, from the acute hospital perspective.

Methods and design: 
A multisite prospective study will be conducted as part of a larger falls-prevention clinical trial—the 6-PACK project. This study will involve 12 acute medical and surgical wards from six hospitals across Australia. Patient and admission characteristics, outcome and hospitalisation cost data will be prospectively collected on approximately 15 000 patients during the 15-month study period. A review of all inhospital fall events will be conducted using a multimodal method (medical record review and daily verbal report from the nurse unit manager, triangulated with falls recorded in the hospital incident reporting and administrative database), to ensure complete case ascertainment. Hospital clinical costing data will be used to calculate patient-level hospitalisation costs incurred by a patient during their inpatient stay. Additional hospital and hospital resource utilisation costs attributable to inhospital falls and fall-related injuries will be calculated using linear regression modelling, adjusting for a prioridefined potential confounding factors.

Discussion:
This protocol provides the detailed statement of the planned analysis. The results from this study will be used to support healthcare planning, policy making and allocation of funding relating to falls prevention within acute hospitals.

O conceito de participação em João Escoto Eriúgena

This thesis aims at studying the concept of participation according to John Scotus Eriugena. The development of our research is based on an identification of Eriugena s sources, investigating the concept of participation since Dyonisus and the Greek Christian fathers, until the Periphyseon. To Eriúgena, the terms that are brought together in participation God, causes, and effects are, while everything that falls out of participation is not. Leaning on his understanding of the relation between cause and effect, according to which the effects participate in the cause and somehow are contained in it, he told us that all things and beings subsist eternally in God, and that God can signify Himself through the created things and beings. To Eriugena, creatures exist because they participate in the Divine Nature and receive their being from It, for nothing truly exists outside of It.

Modos de aplicação de calcário e de micronutrientes em pomar de laranjeira 'Natal' e análise comparativa de custos

De acordo com o Agrianual (2005), a produção citrícola brasileira é de 17,7 milhões de toneladas ano-1,ocupando aproximadamente 1 milhão de hectares no território brasileiro e, deste total, 810 mil hectares localizam-se no Estado de São Paulo. A maioria dos solos brasileiros, inclusive aqueles onde foram instalados os pomares cítricos, apresenta reação ácida. Esta é, sem dúvida, a principal condição desfavorável dos solos e um dos fatores limitantes da produção em solos tropicais. O presente trabalho teve por objetivo estudar o efeito de diferentes modos de aplicação de calcário e de micronutrientes e analisar, de forma comparativa, os custos destes tratamentos em um pomar de laranjeira. O experimento foi desenvolvido na Fazenda Morumbi, município de Estrela D'Oeste-SP, num Argissolo Vermelho-Amarelo. A variedade de laranjeira utilizada foi a 'Natal', enxertada em limão Cravo, com 6 anos de idade e espaçamento 5 x 8 m. O delineamento experimental foi em parcelas subdivididas, com 3 repetições, com 5 tratamentos principais (sem calcário; a necessidade total de calcário (NC) incorporado; NC sem incorporação; ¹/2 NC no primeiro ano + ¹/2 NC no segundo ano e ¹/3 NC no primeiro ano, + ¹/3 NC no segundo ano, + ¹/3 NC no terceiro ano) e dois tratamentos secundários [micronutrientes via solo (FTE-BR 12: 11,5 % de ZnO e B2O3; 1% CuO; 5,4% de Fe2O3; 5,5% de MnO2; 0,2% de MoO3) e micronutrientes via foliar (sulfato de zinco a 0,5% e ácido bórico a 0,08%)], distribuídos em blocos casualizados. Não houve efeito significativo dos modos de aplicação da calagem e de micronutrientes sobre as variáveis avaliadas (produção, sólidos solúveis totais, acidez total titulável). Para massa média do fruto, o efeito significativo aconteceu apenas no primeiro ano, com a calagem em dose única e sem incorporação, e micronutrientes via solo. Concluiu-se que não houve efeito significativo dos modos de aplicação do calcário e dos micronutrientes para produção e massa média dos frutos da laranjeira 'Natal', e a receita líquida foi positiva em todos os tratamentos, sendo que o tratamento 5 [¹/3 da necessidade total de calcário (NC) no 1º ano + ¹/3 da NC no 2º ano, + ¹/3 da NC no 3º ano] apresentou o melhor valor acumulado (U$ 3.721,85 ha-1).

Sub-registro de acidentes do trabalho em localidade do Estado de São Paulo, 1997

OBJETIVO: Estimar o número de acidentes do trabalho ocorridos em determinada localidade e intervalo de tempo e a extensão do sub-registro de casos. MÉTODOS: Amostraram-se 4.782 domicílios residenciais do município de Botucatu, SP, contendo 17.219 moradores, em primeiro de julho de 1997. em cada um dos domicílios, um morador adulto era entrevistado para identificar ocorrência de acidentes do trabalho nos três meses precedentes à entrevista. Nos casos positivos, os acidentados foram entrevistados. Para cálculo do intervalo de confiança utilizou-se a formula de Cochran. RESULTADOS: Confirmaram ter sofrido acidente do trabalho 76 indivíduos, estimando-se em 1.810 o número desses eventos em Botucatu no ano de 1997 e a proporção de incidência em 4,1% (IC95% 3,0%-5,3%). Dos 76 acidentados, 39 não eram cobertos pelo seguro acidente previdenciário (51,3% IC95% 41,1%-61,6%), não se enquadrando na obrigatoriedade de emissão de Comunicação de Acidente do Trabalho (funcionários públicos estatutários, autônomos, assalariados sem registro em carteira, proprietários e outros). Dentre os 37 casos com obrigatoriedade de emissão desse documento, 20 casos não possuíam (54,1% IC39,4%-68,7%). Houve maior proporção de sub-registro de casos em trabalhadores de micro, pequenas e médias empresas, do que entre grandes empresas. Apenas 22,4% (IC13,8%, 30,9%) dos acidentes do trabalho informados nas entrevistas domiciliares foram captados pelos registros previdenciários CONCLUSÕES: Os achados indicam a necessidade de melhoria de utilização de outras fontes de informação, além das Comunicações de Acidentes do Trabalho, para elaboração das estatísticas oficiais sobre acidentes do trabalho.

Exhumation of high-pressure granulites of the Guaxupe Complex, southeastern Brazil

This paper describes tectonic and metamorphic features of Precambrian rocks from the Guaxupe Complex and Varginha Shear Zone (VSZ) near the city of Guaxupe in the southern part of the Sao Francisco Craton, southeastern Brazil. The VSZ separates the metasediments of Araxa Group to the north from the granulites of Guaxupe Complex to the south. The sinistral transcurrent VSZ crosses the entire area striking approximately E-W, bending towards SE in the eastern part. Because of this bend, transpressional movement occurred, facilitating the exhumation of the garnet-rich rocks of the deepest exposed part of the granulite-facies terrane.In the garnet granulites the highest pressure-temperature conditions recorded are approximately 1040 degreesC and 14.4 kbar. The rocks underwent decompression from 14.0 kbar to 8.0 kbar, cooling from 980 degreesC to 710 degreesC, the retrograde path following the boundary between the kyanite and sillimanite stability fields. This interval is interpreted to record the uplift of the lower crustal granulite-facies terrane and re-equilibration during magmatic intrusions. For the felsic granulites an interval of 700-810 degreesC and 8.0-11.5 kbar was attained, also pointing to regional decompression.The granulites of the Guaxupe Complex comprise a medium- to high-pressure lower-crustal terrane, with local occurrences of higher-pressure garnet-rich gneisses, which were uplifted along a transpressional segment of the VSZ. Copyright (C) 2000 John Wiley & Sons, Ltd.

Effect of light-curing units on push-out fiber post bond strength in root canal dentin

The purpose of this study was to evaluate the effectiveness of different light-curing units on the bond strength (push-out) of glass fiber posts in the different thirds of the root (cervical, middle and apical) with different adhesive luting resin systems (dual-cure total-etch; dual-cured and self-etch bonding system; and dual-cure self-adhesive cements), Disks of the samples (n = 144) were used, with approximately 1 mm of thickness of 48 bovine roots restored with glass fiber posts, that were luted with resin cements photo-activated by halogen LCU (QTH, Optilux 501) and blue LED (Ultraled), with power densities of 600 and 550 mW/cm 2, respectively. A universal testing machine (MTS 810 Material Test System) was used with a 1 mm diameter steel rod at cross-head speed of 0.5 mm/min until post extrusion, with load cell of 50 kg, for evaluation of the push-out strength in the different thirds of each sample. The push-out strength values in kgf were converted to MPa and analyzed through Analysis of Variance and Tukey's test, at significance level of 5%. The results showed that there were no statistical differences between the QTH and LED LCUs. The self-adhesive resin cement had lower values of retention. The total-etch and self-adhesive system resin cements seem to be a possible alternative for glass fiber posts cementation into the radicular canal and the LED LCU can be applied as an alternative to halogen light on photo-activation of dual-cured resin cements. © 2009 Pleiades Publishing, Ltd.

Influência do sistema de cimentação adesiva e da fonte de luz fotoativadora na resistência à extrusão de pinos de fibra de vidro

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação da efetividade de cimentos resinosos auto-adesivos aplicados sob diferentes pré-tratamentos da dentina radicular na resistência adesiva de pinos de fibra de vidro

Pós-graduação em Ciências Odontológicas - FOAR

Desoxinivalenol em farinha de trigo: otimização de método analítico, validação e ocorrência

Pós-graduação em Alimentos e Nutrição - FCFAR

Sapro-Zoonotic Risks Posed by Wild Birds in Agricultural Landscapes

There are over 1400 catalogued human pathogens, with approximately 62% classified as zoonotic (Taylor et al., 2001). Most evidence of direct transmission of pathogens to humans involves domestic and companion animals, whereas the reservoir for most zoonoses is wildlife; yet there are relatively few well-documented cases for the direct involvement of transmission from wildlife to humans (Kruse et al., 2004). In part, this absence of evidence reflects the mobility of wildlife, the difficulty accessing relevant samples, and the smaller number of studies focused on characterizing wildlife pathogens relative to the human and veterinary literature (McDiarmid, 1969; Davis et al., 1971; Hubalek, 2004).

High precision astrometry mission for the detection and characterization of nearby habitable planetary systems with the Nearby Earth Astrometric Telescope (NEAT)

A complete census of planetary systems around a volume-limited sample of solar-type stars (FGK dwarfs) in the Solar neighborhood (d a parts per thousand currency signaEuro parts per thousand 15 pc) with uniform sensitivity down to Earth-mass planets within their Habitable Zones out to several AUs would be a major milestone in extrasolar planets astrophysics. This fundamental goal can be achieved with a mission concept such as NEAT-the Nearby Earth Astrometric Telescope. NEAT is designed to carry out space-borne extremely-high-precision astrometric measurements at the 0.05 mu as (1 sigma) accuracy level, sufficient to detect dynamical effects due to orbiting planets of mass even lower than Earth's around the nearest stars. Such a survey mission would provide the actual planetary masses and the full orbital geometry for all the components of the detected planetary systems down to the Earth-mass limit. The NEAT performance limits can be achieved by carrying out differential astrometry between the targets and a set of suitable reference stars in the field. The NEAT instrument design consists of an off-axis parabola single-mirror telescope (D = 1 m), a detector with a large field of view located 40 m away from the telescope and made of 8 small movable CCDs located around a fixed central CCD, and an interferometric calibration system monitoring dynamical Young's fringes originating from metrology fibers located at the primary mirror. The mission profile is driven by the fact that the two main modules of the payload, the telescope and the focal plane, must be located 40 m away leading to the choice of a formation flying option as the reference mission, and of a deployable boom option as an alternative choice. The proposed mission architecture relies on the use of two satellites, of about 700 kg each, operating at L2 for 5 years, flying in formation and offering a capability of more than 20,000 reconfigurations. The two satellites will be launched in a stacked configuration using a Soyuz ST launch vehicle. The NEAT primary science program will encompass an astrometric survey of our 200 closest F-, G- and K-type stellar neighbors, with an average of 50 visits each distributed over the nominal mission duration. The main survey operation will use approximately 70% of the mission lifetime. The remaining 30% of NEAT observing time might be allocated, for example, to improve the characterization of the architecture of selected planetary systems around nearby targets of specific interest (low-mass stars, young stars, etc.) discovered by Gaia, ground-based high-precision radial-velocity surveys, and other programs. With its exquisite, surgical astrometric precision, NEAT holds the promise to provide the first thorough census for Earth-mass planets around stars in the immediate vicinity of our Sun.

Spike-triggered reaction-time EEG as a possible assessment tool for driving ability

The impact of interictal epileptic activity (IEA) on driving is a rarely investigated issue. We analyzed the impact of IEA on reaction time in a pilot study. Reactions to simple visual stimuli (light flash) in the Flash test or complex visual stimuli (obstacle on a road) in a modified car driving computer game, the Steer Clear, were measured during IEA bursts and unremarkable electroencephalography (EEG) periods. Individual epilepsy patients showed slower reaction times (RTs) during generalized IEA compared to RTs during unremarkable EEG periods. RT differences were approximately 300 ms (p < 0.001) in the Flash test and approximately 200 ms (p < 0.001) in the Steer Clear. Prior work suggested that RT differences >100 ms may become clinically relevant. This occurred in 40% of patients in the Flash test and in up to 50% in the Steer Clear. When RT were pooled, mean RT differences were 157 ms in the Flash test (p < 0.0001) and 116 ms in the Steer Clear (p < 0.0001). Generalized IEA of short duration seems to impair brain function, that is, the ability to react. The reaction-time EEG could be used routinely to assess driving ability.

Functionalisation of PLLA nanofiber scaffolds using a possible cooperative effect between collagen type I and BMP-2: impact on colonization and bone formation in vivo

The reconstruction of large bone defects after injury or tumor resection often requires the use of bone substitution. Artificial scaffolds based on synthetic biomaterials can overcome disadvantages of autologous bone grafts, like limited availability and donor side morbidity. Among them, scaffolds based on nanofibers offer great advantages. They mimic the extracellular matrix, can be used as a carrier for growth factors and allow the differentiation of human mesenchymal stem cells. Differentiation is triggered by a series of signaling processes, including integrin and bone morphogenetic protein (BMP), which act in a cooperative manner. The aim of this study was to analyze whether these processes can be remodeled in artificial poly-(l)-lactide acid (PLLA) based nanofiber scaffolds in vivo. Electrospun matrices composed of PLLA-collagen type I or BMP-2 incorporated PLLA-collagen type I were implanted in calvarial critical size defects in rats. Cranial CT-scans were taken 4, 8 and 12 weeks after implantation. Specimens obtained after euthanasia were processed for histology and immunostainings on osteocalcin, BMP-2 and Smad5. After implantation the scaffolds were inhomogeneously colonized and cells were only present in wrinkle- or channel-like structures. Ossification was detected only in focal areas of the scaffold. This was independent of whether BMP-2 was incorporated in the scaffold. However, cells that migrated into the scaffold showed an increased ratio of osteocalcin and Smad5 positive cells compared to empty defects. Furthermore, in case of BMP-2 incorporated PLLA-collagen type I scaffolds, 4 weeks after implantation approximately 40 % of the cells stained positive for BMP-2 indicating an autocrine process of the ingrown cells. These findings indicate that a cooperative effect between BMP-2 and collagen type I can be transferred to PLLA nanofibers and furthermore, that this effect is active in vivo. However, this had no effect on bone formation. The reason for this seems to be an unbalanced colonization of the scaffolds with cells, due to insufficient pore size.