Antipologia medica en respuesta de una apologia del eruditissimo doctor Duarte Nuñez de Acosta ... sobre la decision de dos graves dificultades, que inquieren, si en el rapto incipiente de humor a la Cabeça, convenga medicamento electivo? y en la perlesia en que se empezo a descargar la apoplexia, se deva sangrar del lado Paralitico? /

Mode of access: Internet.

Leal conselheiro e livro da ensinança de bem cavalgar toda sella, escritos pelo senhor dom Duarte, rei de Portugal e do Algarve e senhor de Ceuta;

Mode of access: Internet.

Leal conselheiro, o qual fez dom Duarte. Seguido do livro da ensinança de bem cavalgar toda sella.

Mode of access: Internet.

Cartas a Duarte Ribeiro de Macedo.

Binding:-Cartas de Vieyra, 4.

Portugal conuenzida con la razon para ser venzida con las ... armas de don Philippe IV ... emperador de las Españas ... : sobre la iustissima recuperacion de aquel reyno y la iusta prision de don Duarte de Portugal ... : diuidida en cinco tratados ... /

Mode of access: Internet.

Vida do infante Dom Duarte

Also published from the original (?) manuscript (formerly in the possession of José Freire Monterroyo Mascarenhas) in the Revista litteraria of Porto, 1842, Vol. IX, p. 433-467. cf. Silva, v. I, p. 67.

Cronica delrey dom Affomsso Hamrriques, primeiro rey destes regnos de Portuguall por Duarte Galluam ...

D'esta Cronica foi feita uma unica tiragem de duzentos exemplares ... no. 163.

Amélia Duarte Machado, a Viúva Machado: a esposa, a viúva e a lenda na Cidade do Natal (1900-1930)

The research project examines representations elaborated about Amelia Duarte Machado, images that were built in a particular space: the Natal City. Amelia, one mossoroense that has a simple life, stated a luxurious life after marrying with a rich Portuguese merchant Manuel Machado, in 1904. She led a life of society lady, lived in a sumptuous residence, traveled to Europe, attending the Theatre the city and took care of the social image of her husband, opening the doors of your home to promote dinners and receptions. Experienced the changes occurring in Natal in the first three decades of the twentieth century, when the initiative of a political and intellectual elite of the city began to incorporate bourgeois values and to provide a technical framework focused on the improvements brought by the Industrial Revolution. In 1934, with her husband's death, took over the family business. Besides the widow, also became an enterprising woman. The widow Amelia Machado also became the target of suspicion of the population, rumors about his life. From there emerges a frightening figure in Natal, a being that captured and ate the liver of children, the papa-figo of Natal City, the Widow Machado. In this research, we relate different images that circulated about this woman, who was society lady, dashing widow and papa-figo, articulating these representations with the discourse on female circulating in Natal from 1900 to 1930 yet will raise hypotheses about the creation of the Legend of the Widow Machado

Melhoria da Atenção à Saúde da Pessoa com Hipertensão Arterial Sistêmica e/ou Diabetes Mellitus na UBS Salem Duarte, Mossoró/RN

A Hipertensão Arterial Sistêmica é um grave problema de saúde pública no Brasil e no mundo. Sua prevalência no Brasil varia entre 22% e 44% para adultos (32% em média), chegando a mais de 50% para indivíduos com 60 a 69 anos e 75% em indivíduos com mais de 70 anos. Já a prevalência de Diabetes Mellitus nos países da América Central e do Sul foi estimada em 26,4 milhões de pessoas e projetada para 40 milhões, em 2030. Por conta disso, minha equipe da Unidade Básica de Saúde Salem Duarte optou por realizar a intervenção com o foco nesses temas, pois são doenças que tem uma alta incidência e prevalência e muita demanda de usuários na UBS. O objetivo da intervenção foi melhorar a atenção à pessoa com hipertensão e/ou diabetes Mellitus na UBS Salem Duarte, Mossoró/RN. Foi desenvolvido no período de quatro meses (março, abril, maio, junho) e participaram da intervenção todos os hipertensos e diabéticos de nossa área de trabalho da UBS. As ações realizadas na intervenção foram baseadas nos Cadernos de Atenção Básica n. 36 e 37 (2013), que apontam estratégias para o cuidado das pessoas com essas doenças crônicas. Foram definidos sete objetivos e estabelecidos metas e ações para a melhoria do acesso e qualidade em quatro eixos (organização e gestão do serviço, monitoramento e avaliação, engajamento público e qualificação da prática clínica). Trabalhamos com uma estimativa de 624 usuários hipertensos e 162 diabéticos (segum dados do caderno de ação programática). Nos quatro meses foram alcançados uma cobertura de 84,1% (525) e 100% (162) respectivamente. Do ponto de vista quantitativo, foi importante a cobertura alcançada para os usuários diabéticos, maior da planejada inicialmente (95%). Do ponto de vista qualitativo os melhores resultados aconteceram com a orientação nutricional sobre alimentação saudável, prática de atividade física regular, orientação sobre risco do tabaquismo, sobre higiene bucal, além de estratificação de risco cardiovascular, exame complementares em dia e adequado registro na ficha de acompanhamento. Todos esses indicadores foram alcançados em 100% tanto com os hipertensos, quanto com os diabéticos. As atividades com a comunidade foram satisfatórias, pois muitos usuários puderam aprimorar seus conhecimentos sobre a existência do Programa de Atenção à Hipertensão Arterial e à Diabetes Mellitus, compreendendo melhor sobre características, complicações e prevenção das suas doenças, além de conhecerem os direitos em relação à manutenção de seus registros de saúde. O vínculo entre profissionais – usuários – família foi maior. A intervenção exigiu uma maior preparação para a equipe e promoveu o trabalho em equipe. A UBS teve uma organização mais detalhada dos diferentes arquivos de atendimento dos usuários, assim como maior qualidade do acolhimento e otimização da agenda para a atenção.

Pipkiiα Is Widely Expressed In Hematopoietic-derived Cells And May Play A Role In The Expression Of Alpha- And Gamma-globins In K562 Cells.

Characterized for the first time in erythrocytes, phosphatidylinositol phosphate kinases (PIP kinases) belong to a family of enzymes that generate various lipid messengers and participate in several cellular processes, including gene expression regulation. Recently, the PIPKIIα gene was found to be differentially expressed in reticulocytes from two siblings with hemoglobin H disease, suggesting a possible relationship between PIPKIIα and the production of globins. Here, we investigated PIPKIIα gene and protein expression and protein localization in hematopoietic-derived cells during their differentiation, and the effects of PIPKIIα silencing on K562 cells. PIPKIIα silencing resulted in an increase in α and γ globins and a decrease in the proliferation of K562 cells without affecting cell cycle progression and apoptosis. In conclusion, using a cell line model, we showed that PIPKIIα is widely expressed in hematopoietic-derived cells, is localized in their cytoplasm and nucleus, and is upregulated during erythroid differentiation. We also showed that PIPKIIα silencing can induce α and γ globin expression and decrease cell proliferation in K562 cells.

[theoretical Construction In The Sociology Of Health: A Reflection On Its Trajectory].

The scope of this paper is to reflect on the theoretical construction in the constitution of the sociology of health, still called medical sociology in some countries. Two main ideas constitute the basis for this: interdisciplinarity and the degree of articulation in the fields of medicine and sociology. We sought to establish a dialogue with some dimensions - macro/micro, structure/action - that constitute the basis for understanding medicine/health in relation to the social/sociological dimension. The main aspects of these dimensions are initially presented. Straus' two medical sociologies and the theory/application impasses are then addressed, as well as the dilemmas of the sociology of medicine in the 1960s and 1970s. From these analyses the theoretical production before 1970 is placed as a counterpoint. Lastly, the sociology of health is seen in the general context of sociology, which underwent a fragmentation process from 1970 with effects in all subfields of the social sciences. This process involves a rethinking of the theoretical issues in a broadened spectrum of possibilities. The 1980s are highlighted when theoretical issues in the sociology of health are reinvigorated and the issue of interdisciplinarity is once again addressed.

[the Sociology Of Health In Brazil - The Creation Of An Identity].

This article analyzes the historical, social and cognitive dimensions of the sociology of medicine in the construction of its identity, from Wolf Lepenies' perspective. It is understood that the construction of an identity does not end with the first historical manifestations, but is consolidated when it is institutionalized and structured as a field of knowledge by creating its own forms of cognitive expression. The text is divided into three parts: in the first the precursors are presented, highlighting the role played by some travelers, naturalists and folklore scholars, followed by social physicians-scientists and the first social scientists (1940-1969). In the second part, aspects of the consolidation of the social sciences in health are presented at two significant moments, namely the 1970s and 1980s. In the third part, the issues raised by the field are addressed in general terms. It is considered that once the main structural stages are in place there is still a need for the formation of new generations of social scientists in health. It is also essential to disseminate scientific production and to ensure that the relations are studied in depth and institutionalized with the sociological matrices on the one hand and with the field of health on the other.

[almost An Autobiography: A Study Of Social Scientists In Health Based On The Lattes Curriculum].

Among the various ways of adopting the biographical approach, we used the curriculum vitaes (CVs) of Brazilian researchers who work as social scientists in health as our research material. These CVs are part of the Lattes Platform of CNPq - the National Council for Scientific and Technological Development, which includes Research and Institutional Directories. We analyzed 238 CVs for this study. The CVs contain, among other things, the following information: professional qualifications, activities and projects, academic production, participation in panels for the evaluation of theses and dissertations, research centers and laboratories and a summarized autobiography. In this work there is a brief review of the importance of autobiography for the social sciences, emphasizing the CV as a form of autobiographical practice. We highlight some results, such as it being a group consisting predominantly of women, graduates in social sciences, anthropology, sociology or political science, with postgraduate degrees. The highest concentration of social scientists is located in Brazil's southern and southeastern regions. In some institutions the main activities of social scientists are as teachers and researchers with great thematic diversity in research.

[collective Health Paradigms: A Brief Reflection].

The article discusses the possibility of applying Kuhn's concept of paradigm to collective health. The concept and its use in epidemiology, planning and the social sciences are reviewed briefly. The study stresses the multi-paradigmatic character of collective health, resulting from the convergence of multiple epistemologies and the involvement of diverse fields such as the biological sciences, philosophy, the social sciences and humanities.

Profile Of The Use Of Disease Modifying Drugs In The Brazilian Registry Of Spondyloarthritides.

Few studies have evaluated the profile of use of disease modifying drugs (DMD) in Brazilian patients with spondyloarthritis (SpA). A common research protocol was applied prospectively in 1505 patients classified as SpA by criteria of the European Spondyloarthropathies Study Group (ESSG), followed at 29 referral centers in Rheumatology in Brazil. Demographic and clinical variables were obtained and evaluated, by analyzing their correlation with the use of DMDs methotrexate (MTX) and sulfasalazine (SSZ). At least one DMD was used by 73.6% of patients: MTX by 29.2% and SSZ by 21.7%, while 22.7% used both drugs. The use of MTX was significantly associated with peripheral involvement, and SSZ was associated with axial involvement, and the two drugs were more administered, separately or in combination, in the mixed involvement (p < 0.001). The use of a DMD was significantly associated with Caucasian ethnicity (MTX , p = 0.014), inflammatory back pain (SSZ, p = 0.002) , buttock pain (SSZ, p = 0.030), neck pain (MTX, p = 0.042), arthritis of the lower limbs (MTX, p < 0.001), arthritis of the upper limbs (MTX, p < 0.001), enthesitis (p = 0.007), dactylitis (MTX, p < 0.001), inflammatory bowel disease (SSZ, p < 0.001) and nail involvement (MTX, p < 0.001). The use of at least one DMD was reported by more than 70% of patients in a large cohort of Brazilian patients with SpA, with MTX use more associated with peripheral involvement and the use of SSZ more associated with axial involvement.