Doses de superfosfato simples na produção da berinjela ‘ciça’ em cassilândia (MS) Brasil

The objective of this experiment was to evaluate the answer of the eggplant (Solanum melongena L.) submitted to different applied match doses in the planting hole. The treatments were composed by four doses of simple superphosphate (0, 1000, 2000, 3000 kg.ha-1), the experimental design was randomized block, with five repetitions, tends each unit experimental four plants. The phosphorus fertilized soil propitiated increase of the diameter of the lap of the adult plant, of the number of fruits for plant and productivity of fruits; could be used doses among 1814 to 2054 kg ha-1 of simple superphosphate in the conditions of Cassilandia (State of Mato Grosso do Sul - Brazil).

Cancer intelligence acquired (CIA): tumor glycosylation and sialylation codes dismantling antitumor defense

Aberrant glycosylation is a key feature of malignant transformation and reflects epigenetic and genetic anomalies among the multitude of molecules involved in glycan biosynthesis. Although glycan biosynthesis is not template bound, altered tumor glycosylation is not random, but associated with common glycosylation patterns. Evidence suggests that acquisition of distinct glycosylation patterns evolves from a ‘microevolutionary’ process conferring advantages in terms of tumor growth, tumor dissemination, and immune escape. Such glycosylation modifications also involve xeno- and hypersialylation. Xeno-autoantigens such as Neu5Gc-gangliosides provide potential targets for immunotherapy. Hypersialylation may display ‘enhanced self’ to escape immunosurveillance and involves several not mutually exclusive inhibitory pathways that all rely on protein–glycan interactions. A better understanding of tumor ‘glycan codes’ as deciphered by lectins, such as siglecs, selectins, C-type lectins and galectins, may lead to novel treatment strategies, not only in cancer, but also in autoimmune disease or transplantation.

Uwagi w kwestyi włościańskiéj, ruskiéj i żydowskiéj : z powodu obecnych wypadków

przez Władysława Dzwonkowskiego