835 resultados para C 71, D 63
Resumo:
Tít. tomado del incipit en h. 2r
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Sign.: a8, b6, c8, d6, e8, f6, g8, h6, i8, k6, l8, m6, n8, o6, p8, q6, r8, s6, t8, u6, x8, y6, z8, A6, B8, C6, D8, E6, F8, G6, H8, I6, K8, L6, M8, N6, O8, P6, Q8, R6, S8, T6, U8, X6, Y8, Z6, 2A8, 2B6, 2C8, 2D-2F6
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The putative catalytic domain (residues 81–401) of a predicted tomato protein with similarity to 4-diphosphocytidyl-2-C-methyl-d-erythritol kinase of Escherichia coli was expressed in a recombinant E. coli strain. The protein was purified to homogeneity and was shown to catalyze the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2-C-methyl-d-erythritol at a rate of 33 μmol⋅mg−1⋅min−1. The structure of the reaction product, 4-diphosphocytidyl-2-C-methyl-d-erythritol 2-phosphate, was established by NMR spectroscopy. Divalent metal ions, preferably Mg2+, are required for activity. Neither the tomato enzyme nor the E. coli ortholog catalyzes the phosphorylation of isopentenyl monophosphate.
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Esta tesis doctoral persigue una revalorización del papel jugado por los senadores que gobernaron las provincias hispanas a lo largo de un período crucial de la historia de Roma, el Principado, cuando se convirtió en un imperio que aseguró su perduración con la progresiva integración socio-política de los provinciales, en particular de las élites. Los gobernadores de rango senatorial eran los más poderosos “men on the spot” del Imperio en su periferia, pero los estudios dedicados a ellos son parciales o tienen una perspectiva demasiado amplia, y generalmente tienden a favorecer los ejemplos ofrecidos por las provincias orientales –a causa de sus más abundantes fuentes de sus ciudades. Este estudio busca analizar la influencia de los gobernadores en las relaciones centro-periferia en Occidente a través del caso específico de Hispania, un caso de estudio especialmente apropiado porque permite comparar el modus operandi y las relaciones sociales de gobernadores de dos provincias imperiales (Hispania Citerior y Lusitania) y de una proconsular (Bética) y analizar su influencia en la vida de las comunidades de algunas de las áreas más romanizadas de Occidente – el valle del Betis y la costa levantina– y en aquéllas de una región conquistada al inicio del Principado: el Noroeste. La metodología de este estudio está condicionada por la naturaleza de las fuentes: literarias (Plinio el Joven, Tácito, Dión Casio, Floro, Orosio….), epigráficas leyes municipales, epistulae imperiales, senadoconsultos, sentencias judiciales, inscripciones votivas y honoríficas), los autores clásicos jurisprudenciales del Digesto (de officio proconsulis de Ulpiano…) y, en menor medida, numismáticas (particularmente la caetra)...
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No abstract.
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This contribution starts with the examination of the recent Italian Law on Apprenticeship (Decree n° 167 of 2011) in the light of the European regulation, namely that one coming from EU. Then, the European regulations of Apprenticeship - that is to say the regulations in some EU Member States - are analysed. Those rules shows some unexpected similarities among the different legal systems, which suggest the proposal of a new EU Directive that could regulate some issues of Apprenticeship.
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'Common places', as argued in this paper, may at times fulfil a persuasive function. This is the case of messages enshrined in Europe 2020. In the aftermath of an unprecedented economic and financial crisis they may sound like common places. European institutions have given precedence to measures on financial and budgetary stability, thus marginalising social and employment policies. The only promising developments, the 'new places' in labour law, must be searched in the new synergies among employment and cohesion policies. National and subnational levels of decison-making should be favoured in order to attain the delivery of new partnership agreements, supported by European structural funds.
Resumo:
The paper analyzes the ECJ case law on fixed-term work, with specific regard to non-regression clause, measures to prevent abuses and the principle of non-discrimination. In particular, the Author points out that the principle of non-discrimination is to be regarded as being the core of the fixed-term work regulation; in this respect, especially in more recent judgments, the Court seems to maximize the scope of such principle.