Information access law and disclosing of information by joint-stock companies in Brazil: open data and Extensible Business Reporting Language (XBRL) standard

The strategic management of information plays a fundamental role in the organizational management process since the decision-making process depend on the need for survival in a highly competitive market. Companies are constantly concerned about information transparency and good practices of corporate governance (CG) which, in turn, directs relations between the controlling power of the company and investors. In this context, this article presents the relationship between the disclosing of information of joint-stock companies by means of using XBRL, the open data model adopted by the Brazilian government, a model that boosted the publication of Information Access Law (Lei de Acesso à Informação), nº 12,527 of 18 November 2011. Information access should be permeated by a mediation policy in order to subsidize the knowledge construction and decision-making of investors. The XBRL is the main model for the publishing of financial information. The use of XBRL by means of new semantic standard created for Linked Data, strengthens the information dissemination, as well as creates analysis mechanisms and cross-referencing of data with different open databases available on the Internet, providing added value to the data/information accessed by civil society.

Uma reflexão histórica e crítica sobre música e educação: análise do projeto de lei do Senado n. 330 de 2006 que deu origem à Lei n. 11.769, de 18 de agosto de 2008

The objective of this study is to analyze the trajectory of the bill the Senate No. 330 of 2006 that led to Law no. 11,769 of 18 August 2008, amending Article 26 of the Law of Directives and Bases of Education (Act 9394 of 1996) to be held about the mandatory teaching of music in primary education, after more than 30 years of absence from the scene national public education, until to be sanctioned with partial veto, noting the historical importance of this artistic aspect as widely performed in various ways and for many different purposes. The return of the compulsory teaching of music reappears in the realms of teaching systematized public by bringing the possibility of thinking about music, see it beyond the medias execute that permeate society today.

Synergistic inhibition of tumor growth in a murine mammary adenocarcinoma model by combinational gene therapy using IL-12, pro-IL-18, and IL-1β converting enzyme cDNA

We report here that a cancer gene therapy protocol using a combination of IL-12, pro-IL-18, and IL-1β converting enzyme (ICE) cDNA expression vectors simultaneously delivered via gene gun can significantly augment antitumor effects, evidently by generating increased levels of bioactive IL-18 and consequently IFN-γ. First, we compared the levels of IFN-γ secreted by mouse splenocytes stimulated with tumor cells transfected with various test genes, including IL-12 alone; pro-IL-18 alone; pro-IL-18 and ICE; IL-12 and pro-IL-18; and IL-12, pro-IL-18, and ICE. Among these treatments, the combination of IL-12, pro-IL-18, and ICE cDNA resulted in the highest level of IFN-γ production from splenocytes in vitro, and similar results were obtained when these same treatments were delivered to the skin of a mouse by gene gun and IFN-γ levels were measured at the skin transfection site in vivo. Furthermore, the triple gene combinatorial gene therapy protocol was the most effective among all tested groups at suppressing the growth of TS/A (murine mammary adenocarcinoma) tumors previously implanted intradermally at the skin site receiving DNA transfer by gene gun on days 6, 8, 10, and 12 after tumor implantation. Fifty percent of mice treated with the combined three-gene protocol underwent complete tumor regression. In vivo depletion experiments showed that this antitumor effect was CD8+ T cell-mediated and partially IFN-γ-dependent. These results suggest that a combinatorial gene therapy protocol using a mixture of IL-12, pro-IL-18, and ICE cDNAs can confer potent antitumor activities against established TS/A tumors via cytotoxic CD8+ T cells and IFN-γ-dependent pathways.

Acesso à informação e intimidade : um dilema do Estado Democrático de Direito

Dissertação (mestrado)—Universidade de Brasília, Faculdade de Direito, Programa de Pós-Graduação em Direito, 2016.

Política nacional de resíduos sólidos

Trata da Lei n. 12.305, de 2 de agosto de 2010, que institui a Política Nacional de Resíduos Sólidos; altera a Lei n° 9.605, de 12 de fevereiro de 1998; e dá outras providências; e legislação correlata

Como a Câmara dos Deputados deve ser em 2023? : pesquisa de opinião abriu espaço para a sociedade opinar sobre o aperfeiçoamento da Instituição

Entre os dias 27 de outubro e 18 de novembro de 2011, a Câmara dos Deputados realizou uma pesquisa de opinião com cidadãos, deputados, servidores da instituição e especialistas para subsidiar o planejamento do Novo Ciclo de Gestão Estratégica 2012-2023.

Legislação sobre licitações e contratos administrativos

Lei nº 8.666, de 21 de junho de 1993, que regulamenta o art. 37, inciso XXI, da Constituição Federal; Lei nº 10.520, de 17 de julho de 2002, Decreto nº 5.450, de 31 de maio de 2005, Lei nº 12.232, de 29 de abril de 2010, Lei nº 12.462, de 4 de agosto de 2011 e Decreto nº 7.892, de 23 de janeiro de 2013.