993 resultados para 332.42


Relevância:

20.00% 20.00%

Publicador:

Resumo:

Al0.58Ga0.42N epilayers are grown by ammonia gas source molecular beam epitaxy (NH3-MBE) on (0001) sapphire substrate using AlGaN buffer layer. The effects of the buffer layer growth temperature on the properties of Al0.58Ga0.42N epilayer are especially investigated. In-situ high-energy electron diffraction (RHEED), double-crystal X-ray diffraction (DCXRD), atomic force microscopy (AFM), photoconductivity measurement and cathodoluminescence (CL) are used to characterize the samples. It is found that high growth temperature of AlGaN buffer layer would improve the crystalline quality, surface smoothness, optical quality and uniformity of the Al0.58Ga0.42N epilayer. The likely reason for such improvements is also suggested. (C) 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Relevância:

20.00% 20.00%

Publicador:

Resumo:

High structural and optical quality 1.3 mu m GaInNAs/GaAs quantum well (QW) samples with 42.5% indium content were successfully grown by molecular beam epitaxy. The growth of well layers was monitored by reflection high-energy electron diffraction (RHEED). Room temperature photoluminescence (PL) peak intensity of the GaIn0.425NAs/GaAs (6 nm / 20 nm) 3QW is higher than, and the full width at half maximum (FWHM) is comparable to, that of In0.425GaAs/GaAs 3QW, indicating improved optical quality due to strain compensation effects by introducing N to the high indium content InGaAs epilayer. The measured (004) X-ray rocking curve shows clear satellite peaks and Pendellosung fringes, suggesting high film uniformity and smooth interfaces. The cross sectional TEM measurements further reveal that there are no structural defects in such high indium content QWs. (c) 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

采用DEAE-sephadex A-50、Sephadex G-100、CM-sepharose cl-6B三步柱层析,从烙铁头(T. mucrosquamatus)蛇毒中纯化得到的精氨酸酯酶在聚丙烯酰胺凝胶电泳(pH 8.3)和SDS-聚丙烯酰胺凝胼电泳中均呈现单一的蛋白带。其分子量为29000,等电点pI为5.2;由225个氨基酸残基组成,其中Gly,Asp和Glu的含量较高。它是一个糖蛋白,含有0.5%的中性已糖和0.75%的唾液酸,对热及酸碱变化较稳定。在280nm波长处有典型的蛋白质吸收峰,此时的消光数E0.1%/1cm为1.332。该酶具有较强的精氨酸酯酶活性和纤维蛋白原溶解活性,无出血活性、酪蛋白水解活性以及粗毒中含有的其它酶活性。从烙铁头(T. mucrosquamatus)蛇毒中纯化的具纤维蛋白原溶解活性的精氨酸酯酶(MFAE)是一丝氨酸蛋白酶,其活性可被PMSF抑制而不受EDTA的影响。MFAE酶促反应的最适pH为8.4,最适温度55 ℃; pH7.6、37 ℃时水解BAEER的米氏常数K_m为20 * 10~(-3)M。该酶能降解纯化人纤维蛋白原的Bβ链以及纯化牛纤维蛋白原的Aα和Bβ链,并有一定的纤维蛋白溶解活性。它能明显延长兔血浆的凝血酶时间和复钙时间。纯化的MFAE无出血活性、凝血酶样活性及血小板聚集活性,对ADP、AA、TMVA、Melittin等诱导的血小板聚集也无抑制或解聚作用。本文还测定了它对凝血酶及胞浆毒特异性合成三肽底物的水解活性。

Relevância:

20.00% 20.00%

Publicador:

Resumo:

在黑白仰鼻猴(Rhinopithecus bieti)分布区北端的南仁(99o04’E, 28o34’N), 野外工作分别于2001年4月10日 - 6月30 日(代表冬末和春季),9月14日 - 12月20日(夏秋季)进行。我们分别用粪便取样法、录像带记录和直接观察法收集了猴群生境的垂直利用、过夜处选择和社会组织数据。此外,我们于1998年8月20日到12月31日在中科院昆明动物研究所老所利用全发生取样法(All-Occurence sampling)收集了一个单雄多雌单元(One-male, multi-female unit: OMU)的性行为数据。另外,我们利用昆明动物所1994 - 2003年和昆明动物园1991 - 2003年笼养黑白仰鼻猴群的出生记录来说明出生季节和出生间隔。 黑白仰鼻猴群全年在3500 - 4300 m的林带上活动,集中利用的海拔带为3900 - 4200 m,这可能与猴群的主食(松萝)主要分布于高海拔有关。冬季, 山沟中的粪便密度高于山脊,这可能是猴群在沟中过夜的缘故。猴群喜欢在树高(27.5 ± 3.2 m)较高、胸径(57.9 ± 16.9 cm)和树冠(6.3 ± 1.4 m)大的针叶树(云冷杉)上过夜。猴群冬季喜欢在阳坡中部的针叶树上过夜,这样既安全又可以接受适量的阳光照射。这是猴群在选择最安全和最暖和过夜处的一种折衷策略。 1994年猴群OMUs大小为7.8 ± 1.7(n = 17),成年性比(M/F)是1.0: 3.8。2001年OMUs大小为10.1 ± 3.7 (n = 15),成年性比是1.0: 4.9。1994-2001年,OMUs中每个成年雌性每年的平均增长率是0.04。这种OMU-band两层社会组织与Kirkpatrick(1996)的报道一致。 雌性以匍匐地面或栖木上,同时面部和视线左右摆动,或者坐着上下移动头部的动作邀配;雄性则以伴有特别的叫声、露齿动颌表情邀配。在有射精记录的观察日中,平均每5.2次爬跨有1次射精,而单次爬跨就射精的仅占4.4%。雌性邀配了18次射精爬跨的大多数(72%),但163次非射精爬跨中她们邀配的仅为45%。雄性在射精交配中叫声多于非射精交配。该种交配模式与其它疣猴亚科动物相似,而性内交配竞争可能与这种模式的进化有关。 笼养黑白仰鼻猴群的出生日期为12 - 6月份,出生高峰期为3 - 5月份。猴群的平均出生日期为4月18日(标准差为43天),中位出生日期为4月10日。猴群的出生间隔平均为624 ± 150天(n = 15,范围:332 - 787天)。幼猴可活到1岁后的出生间隔(706 ± 71, n = 12, 498 - 787天)显著长于1岁内死亡或流产后的出生间隔(428 ± 87, n = 5, 332 - 568天)。婴猴性比(M/F)显著偏离1: 1。

Relevância:

20.00% 20.00%

Publicador:

Resumo:

本实验使用放射化学方法测定了42 MeV/u (12)C与~(115)In相互作用靶余核的生成截面。借助高斯电荷分布的假设得到了靶余核的质量分布。将实验得到的质量分布与熔合碎裂模型和级联的两体衰变模型进行了比较。特别值得注意的是,使用统计的两体衰变模型Monte Carlo GEMINI程序计算第一次与实验结果符合得非常满意。同时计算结果也表明:在42MeV/u的轰击能量下,完全熔合对靶余核的产物仍然有很大的贡献。在同样的假设下,得到了靶余核的同位素分布。可以看到,同位素分布的宽度随靶余核原子序数的增加而增加,在此对利用中能重离子反应生成新的远离β稳定线的缺中子核素进行了讨论

Relevância:

20.00% 20.00%

Publicador:

Resumo:

目的研究文冠果壳苷对侧脑室注射β肽淀粉样蛋白1-4(2Aβ1-42)小鼠学习记忆障碍的改善作用,并初步探讨了其作用机制。方法通过避暗和水迷宫实验检测了小鼠的学习记忆能力;使用分光光度计检测小鼠大脑组织中乙酰胆碱酯酶(AchE)和胆碱乙酰转移酶(ChAT)活性的变化。结果小鼠侧脑室注射凝聚态Aβ1-42显著降低了小鼠被动回避学习记忆能力及空间学习记忆能力(P<0.01),并且小鼠大脑AchE和ChAT活性显著降低(P均<0.05);而文冠果壳苷能够显著减少避暗错误次数,延长潜伏期(分别P<0.05、P<0.01);剂量依赖性地缩短水迷宫实验中小鼠到达安全台的游泳时间(分别P<0.05、P<0.01),不同程度地抑制Aβ1-42模型小鼠的AchE和ChAT活性的降低(P<0.05和<0.01)。结论文冠果壳苷对侧脑室注射Aβ1-42小鼠学习记忆障碍具有显著的改善作用,其作用机制可能与保护中枢胆碱能神经细胞,改善中枢胆碱能神经系统功能等有关。

Relevância:

20.00% 20.00%

Publicador:

Resumo:

多金属氧酸盐因其在医药临床、工业催化、功能材料等方面的广泛应用而引起人们的关注 [1~ 6 ] ,其中 ,有关钒化学的研究一直很活跃 ,钒具有与钼、钨明显不同的结构特性 ,钒可以采取 VO4 ,VO5和VO6 方式配位 ,同时 ,钒的价态可以是 + 3,+ 4和 + 5价 .由于钒可采取多种配位方式及多种价态 ,与钼酸盐和钨酸盐相比 ,钒酸盐更具有结构柔顺性 ,同时易形成低价或混合价态物种 .在以往的文献中 ,有关 P- V- O体系多金属氧酸盐的水热合成的研究已有大量的报道 [7] ,在常规溶液合成中 ,人们已对As- V- O体系进行了相对深入的研究 ,而有关水热合成的研究报道却很少 ,已见报道的砷钒化合物有K6 [As6 V15O4 2 ( H2 O) ]· 6H2 O[8,9] ,[As8V14 O4 2 ( H2 O) 1/2 ]4 - [10 ] ,[As8V14 O4 2 ( X) ]6 - [11] ( X=SO2 - 3,SO2 - 4,H2 O) .为了探究水热条件下 As- V- O体系的反应特性 ,我们开展了这方面的研究工作 ,并取得了突破性进展 .本文采用中温水热技术合成了含有机基团...

Relevância:

20.00% 20.00%

Publicador:

Resumo:

A selenium-containing catalytic antibody (Se-4A4), prepared by converting reactive serine residues of a monoclonal antibody (4A4) raised against a GSH derivative into selenocysteines, acts as a mimic of cytosolic glutathione peroxidase (cGPX). To clarify the mechanism of action of this catalytic antibody, detailed studies on kinetic behaviour and biological activity were carried out. A rate of acceleration (k(cat)/K-m/k(uncat)) 10(7)-fold that of the uncatalytic reaction is observed. Under similar conditions, the turnover number (k(cat)) of Se-4A4 is 42% of that of the natural rabbit liver cGPX. The Se-4A4 reaction involves a Ping Pong mechanism, which is the same as that of the natural cGPX. The selenocysteine residue is located in the binding site of the antibody and is shown to be crucial for this activity. Of the thiol compounds tested, only GSH is able to serve as substrate for Se-4A4. It was demonstrated, using the free-radical-damage system (hypoxanthine/xanthine oxidase) of cardiac mitochondria, that Se-4A4 can protect mitochondria from free-radical damage at least 10(4)-fold more effectively than the natural cGPX.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

自La@C_(82)被发现以来,能导致新分子、新材料不断涌现的金属富勒烯的研究就一直是富勒烯化学领域中最吸引人的分支,但是它的发展比较缓慢,直到K-H方法被应用于宏观量地合成金属富勒烯,这种情况才有所改善.现在,大多数镧系元素,包括La,Ce,Nd,Sm,Eu,Gd,Tb,Dy,Ho和Er,已通过金属/碳棒在低压氦气条件下的电弧放电过程被成功地包裹于富勒烯碳笼当中并被溶剂提取出来,它们提取液的质谱图均给出明显的M@C_(82)信号.与此相反,我们这里报道了一种特殊的镧系元素——镥,在它的金属富勒烯提取液中,只有双镥富勒烯,Lu_2@C_(2n),能被激光解吸电离飞行时间质谱与解吸电子轰击质谱观察到.含富勒烯与双镥富勒烯的碳炱用电弧放电法制备.简单来说,直径6mm的光谱纯碳棒,钻孔,填入99.99%Lu_2O_3与碳粉的混合物,使总原子比为1.0Lu/100C,此金属/碳的混合棒先在真空条件下(10~(-3)×133.332 Pa),2000 K处理3h,然后作为正极在160×133.332 Pa氦气中直流电弧放电,电弧电流80A.生成的碳炱用甲苯索氏提取后,再于高压釜中523 K时,

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Advanced modulation formats have become increasingly important as telecoms engineers strive for improved tolerance to both linear and nonlinear fibre-based transmission impairments. Two important modulation schemes are Duobinary (DB) and Alternate-mark inversion (AMI) [1] where transmission enhancement results from auxiliary phase modulation. As advanced modulation formats displace Return-to-zero On-Off Keying (RZ-OOK), inter-modulation converters will become increasingly important. If the modulation conversion can be performed at high bitrates with a small number of operations per bit, then all-optical techniques may offer lower energy consumption compared to optical-electronic-optical approaches. In this paper we experimentally demonstrate an all-optical system incorporating a pair of hybrid-integrated semiconductor optical amplifier (SOA)-based Mach-Zehnder interferometer (MZI) gates which translate RZ-OOK to RZ-DB or RZ-AMI at 42.6 Gbps. This scheme includes a wavelength conversion to arbitrary output wavelength and has potential for high-level photonic integration, scalability to higher bitrates, and should exhibit regenerative properties [2].

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Practice Links is a free e-publication for practitioners working in Irish social services, voluntary and nongovernmental sectors. Practice Links was created to enable practitioners to keep up-to-date with new publications, electronic resources and conference opportunities. Issue 42 features a report examining the measures undertaken by schools to reduce bulling and victimization.