994 resultados para 197-1206A


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The Marion Allan Wright Papers consist of correspondence, a journal, autobiographical writings, bibliographies, biographical data, essays, speeches, book reviews, short stories, poems, letters to the editor, oral history transcripts and other papers. Subjects include the death penalty, the civil rights movement, civil liberties, libraries in South Carolina and politics. Correspondents include R. Beverly Herbert, L. Mendel Rivers, J, William Fulbright, Sam Ervin, Jr., Reverend James P. Dees, Preston Wright (Wright's brother) and other relatives. See Acc 48 for an earlier accession of Wright papers and the oral history collection for recorded interviews with Wright.

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Cross Reacting Material 197(CRM197) is a Diphteria toxin non toxic mutant that had shown anti-tumor activity in mice and humans. CRM197 is utilized as a specific inhibitor of heparin-binding epidermal growth factor (HB-EGF), that competes for the epidermal growth factor receptor (EGFR), overexpressed in colorectal cancer and implicated in its progression. We evaluated the effects of CRM197 on HT-29 human colon cancer cell line behaviour and, for CRM197 recognized ability to inhibit HB-EGF, its possible effects on EGFR activation. In particular, while HT-29 does not show any reduction of viability after CRM197 treatment, or changes in cell cycle distribution, in EGFR localization or activation, they show a change in gene expression profile analyzed by microarray. This is the first study where the CRM197 treatment on HT-29 show the alteration of a specific and selected number of genes.

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Complications and failures after microvascular free tissue transfer for lower extremity reconstruction have a negative impact on postoperative course and final outcome. Therefore, a 10-year analysis on lower extremity reconstruction with free flaps was performed with a special emphasis on patient co-morbidities such as cardiovascular diseases, diabetes mellitus, body mass index and history of smoking, in order to identify potential risk factors. Complications such as haematoma, seroma, infection, wound dehiscence, as well as partial flap loss, postoperative thrombosis of the anastomosis and eventual total flap loss were gathered from the medical records. Limb salvage was 100%, however 40% suffered from complications ranging from minor wound dehiscence to total flap loss. None of the above-mentioned potential risk factors was associated with an increased rate of complications. However, in flaps that required revision for thrombosis, the age of the patients was significantly higher in the group of flaps that eventually failed when compared to flaps that were salvaged. In conclusion, lower extremity reconstruction with microvascular free tissue transfer is a safe and reliable procedure with a high success rate, however partial flap loss remains an important issue. Increased age was the only factor identified with an increased risk for subsequent flap loss in cases that were revised for thrombosis.

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75 Briefe mit Beilagen zwischen Prof. Frances Bartlett Kinne und Max Horkheimer, 1956-1973; 7 Briefe mit Beilagen zwischen Prof. Otto Kirchheimer und Max Horkheimer, 1952-1954; 19 Briefe mit Beilagen zwischen Prof. Guido Kisch und Max Horkheimer, 1955-1956; 23 Briefe mit Beilagen zwischen Walter Kittel (Oberbaurat i. R.), 1964-1973; 14 Briefe mit Beilagen zwischen Jules Klanfer und Max Horkheimer, 1963-1964; 4 Briefe mit Beilagen zwischen Prof. Otto Klineberg und Max Horkheimer, 1960-1961; 1 Brief von Max Horkheimer an Otto Klineberg (Psychologe), 22.6.1960;

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Vorbesitzer: Dominikanerkloster Frankfurt am Main

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abgedruckt in: Schopenhauer-Jahrbuch 24 (1937), S 119

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Glückwünsche zum 70. Geburtstag, Humoristischer Verein in Boston, Bitte um Übersendung seiner Gedichte

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Vorbesitzer: Karl Konstanz Victor Rücker

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Vorbesitzer: Karl Konstanz Victor Rücker;

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Vorbesitzer: Karl Konstanz Victor Rücker

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Vorbesitzer: Karl Konstanz Victor Rücker