Analysis of the combined effect of lasers of different wavelengths for PDT outcome using 600, 630, and 660 nm

We investigated the effects of photodynamic therapy (PDT) outcome when combining three laser systems that produce light in three different wavelengths (600, 630, and 660 nm). Cooperative as well as independent effects can be observed. We compared the results of the combined wavelengths of light with the effect of single laser for the excitation of the photosensitizer. In the current experiment, the used photosensitizer was Photogem (R) (1.5 mg/kg). Combining two wavelengths for PDT, their cumulative dose and different penetrability may change the overall effect of the fluence of light, which can be effective for increasing the depth of necrosis. This evaluation was performed by comparing the depth and specific aspect of necrosis obtained by using single and dual wavelengths for irradiation of healthy liver of male Wistar rats. We used 15 animals and divided them in five groups of three animals. First, Photogem (R) was administered; follow by measurement of the fluorescence spectrum of the liver before PDT to confirm the level of accumulation of photosensitizer in the tissue. After that, an area of 1 cm(2) of the liver was illuminated using different laser combinations. Qualitative analysis of the necrosis was carried out through histological and morphological study. [GRAPHICS] (a) - microscopic images of rat liver cells, (b) - superficial necrosis caused by PDT using dual-wavelength illumination, (c) - neutrophilic infiltration around the vessel inside the necrosis, and (d) - neutrophilic infiltration around the vessel between necrosis and live tissue (C) 2011 by Astro Ltd. Published exclusively by WILEY-VCH Verlag GmbH & Co. KGaA

Controladoria de gestão na PREVI: modelos, apoio à governança e Lei complementar 108

O segmento de previdência privada fechada tem 3,2 milhões de participantes e assistidos com mais de 1.000 planos de previdência administrados por 330 fundos de pensão (EFPC). Para que essas entidades cumpram a sua missão é necessário um acompanhamento dos recursos acumulados, do desempenho atingido pelos investimentos e a avaliação de se o montante acumulado permite o complemento de renda esperado, e também se faz necessário que os participantes dos planos de previdência tenham acesso às informações de sua performance. Este trabalho abordará o estudo desses fundos de pensão, com foco naqueles cujo patrocínio é de uma entidade pública regida pela Lei Complementar nº108/2001, que disciplina a relação dessas entidades públicas, enquanto patrocinadoras, com suas respectivas entidades fechadas de previdência privada. Há diferenças significativas entre os fundos de pensão e as demais empresas, porém os fundos de pensão passam por problemas similares nos aspectos de gestão e governança. Este trabalho analisará a governança dos fundos de pensão e o papel e atribuições da área de Controladoria, normalmente a responsável por gerar informações para alta administração das empresas em geral, adaptando-as ao contexto da previdência. Como caso prático, será analisada a PREVI - Fundo de Pensão dos Funcionários do Banco do Brasil e sua área de controladoria. A PREVI é uma entidade fechada de previdência complementar, fundada há 109 anos, maior fundo de pensão de América Latina e o 27o do mundo. Atualmente administra três planos de previdência que totalizam mais de R$ 160 bilhões em ativos.

Anti-inflammatory effects of low-level laser therapy (LLLT) with two different red wavelengths (660 nm and 684 nm) in carrageenan-induced rat paw edema

It has been suggested that low-level laser therapy (LLLT) can modulate inflammatory processes. The aim of this experiment was to investigate what effects red laser irradiation with two different wavelengths (660 nm and 684 nm) on carrageenan-induced rat paw edema and histology. Thirty two male Wistar rats were randomly divided into four groups. One group received a sterile saline injection, while inflammation was induced by a sub-plantar injection of carrageenan (1 mg/paw) in the three other groups. After 1 h, LLLT was administered to the paw in two of the carrageenan-injected groups. Continuous wave 660 nm and 684 nm red lasers respectively with mean optical outputs of 30 mW and doses of 7.5 J/cm(2) were used. The 660 nm and 684 nm laser groups developed significantly (P < 0.01) less edema (0.58 ml [SE +/- 0.17] ml and 0.76 ml [SE +/- 0.10] respectively) than the control group (1.67 ml [SE +/- 0.191) at 4 h after injections. Similarly, both laser groups showed a significantly lower number of inflammatory cells in the muscular and conjunctive sub-plantar tissues than the control group.We conclude that both 660 nm and 684 nm red wavelengths of LLLT are effective in reducing edema formation and inflammatory cell migration when a dose of 7.5 J/cm(2) is used. (c) 2007 Elsevier B.V. All rights reserved.

Magmatismo há ca. 660 - 640 Ma no Domínio Socorro: Registros de convergência-colisional na Aglutinação do Gondwana Ocidental

Uranium-lead zircon ages between 660 and 640 Ma, obtained from a series of calc-alkaline orthogneisses and plutons in southeast Brazil's Central Mantiqueira Province, suggest that a significant period of magmatism occurred in this region prior to the collisional assembly of West Gondwana (presently constrained in the region between ca. 625 and 580 Ma). While the nature of this earlier magmatism is presently unclear, some preliminary Sm-Nd data suggest that these magmas were not solely derived from the Paleoproterozoic lithosphere, but appear to represent hybrid products of Paleoproterozoic and Neoproterozoic sources. As such hybrid mixtures have been most commonly observed in continental are settings, it is possible that the 660 to 640 Ma magmatism represents are magmatism that resulted from subduction of Neoproterozoic oceanic crust during early precollisional convergence and closure of a branch of either the Adamastor or Goianides oceans.

Optical limiting behavior of tungstate fluorophosphate glasses

Nonlinear absorption measurements were performed on fluorophosphate glasses with high concentration of tungsten oxide. Large two-photon absorption coefficients, α2, were determined at 660 nm using nanosecond laser pulses. It was observed that α2 increases for increasing tungsten oxide concentrations and therefore the optical limiting performance of this new glass composition can be controlled.

Resolución 660(XXXIV): Comité de Desarrollo y Cooperación del Caribe

Versión en inglés disponible en Biblioteca

Resolution 660(XXXIV) Caribbean Development and Cooperation Committee

Spanish version available

Efeitos da membrana amniótica homógena associada ao laser arseneto de gálio-alumínio (λ=660) na reparação de mucosite oral em ratos tratados com 5-fluoruracila: análise histológica e imunohistoquímica

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Influência do laser em baixa intensidade (660 nm) no processo de reparo de feridas cutâneas provocadas em ratos tratados com nicotina: estudo histológico

Pós-graduação em Odontologia - FOA