Soroepidemiologia de rotavírus em uma população infantil, Goinia, Goiás, Brasil

Amostras de soro de 125 crianças, com idades entre 0 e 10 anos, da população de Goiânia, Goiás, Brasil, geraram um índice de prevalência de anticorpos para rotavirus (ensaio imunoenzimático) de 82,4%. Aparentemente, o maior risco de infecção pelo vírus se dá no grupo de 1 a 3 anos. Não existe diferença de infecção de acordo com o sexo. Informações soroepidemlológicas a nível nacional, são de grande importância para o melhor conhecimento do comportamento do vírus na população em risco, principalmente quando existe a possibilidade de uma futura imuno-profilaxia. O teste imuno-enzimático em comparação com a contraimuno-eletro-osmoforese, mostrou-se mais sensível para a detecção de anticorpos para rotavirus.

Validação fisiológica da dosagem dos metabólitos de glucocorticóides em fezes de Papagaio-verdadeiro (Amazona aestiva)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Validação de método não-invasivo para análise de hormônios ligados ao estresse em papagaio-verdadeiro(Amazona aestiva)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Clonagem e expressão de fragmentos de anticorpos (scFV) contra o vírus da leucemia felina (FeLV) por phage display

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Caracterização genotípica de amostras de Leishmania spp. isoladas de área endêmica para Leishmaniose Visceral Canina no estado de São Paulo

Pós-graduação em Doenças Tropicais - FMB

Síntese e avaliação farmacológica de novos compostos híbridos úteis para tratamento das complicaçôes da anemia falciforme

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Luminescent threat: toxicity of light stick attractors used in pelagic fishery

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Intraocular pressure, specular microscopy, and prostaglandin E-2 concentration in dogs with mature and hypermature cataract

This study aimed to evaluate and correlate intraocular pressure (IOP), endothelial cell density (CD), and hexagonality (HEX), and the aqueous humor prostaglandin E-2 (PGE(2)) concentration in dogs with mature (MG, n = 8) and hypermature (HG, n = 8) cataracts. Eight laboratory beagles with no ocular abnormalities were included as a control group (CG). The IOP was measured using a digital applanation tonometer. Noncontact specular microscopy was used to evaluate CD and HEX. Samples of aqueous humor were used to determine prostaglandin E-2 concentration using enzyme-linked immunoassay. Data were compared by ANOVA and Bonferroni's multiple comparison test, and possible correlations among the PGE(2) aqueous concentration and corneal endothelium cell parameters were assessed by Person's test (P < 0.05). Average values of IOP (P = 0.45) and CD (P = 0.39) were not significantly different between MG, HM, and CG. Average values of HEX were lower, and PGE(2) concentration was increased in the MG and HG in comparison with CG (P < 0.05); however, such parameters did not change significantly between MG and HG (P > 0.05). PGE(2) values did not correlate with IOP, CD, and HEX in any group (P > 0.05). Although there were a small number of dogs studied, our results demonstrated that cataract progression from mature to hypermature did not have a significant change in PGE(2) aqueous concentration, IOP, corneal endothelial cell count, or morphology. In addition, PGE(2) concentration was not correlated with parameters of the corneal endothelium or IOP in dogs with mature or hypermature cataracts.

Pentraxin-3 concentration in the amniotic fluid of women at term, in spontaneous preterm labor and when not in labor

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

High occurrence of Cryptosporidium ubiquitum and Giardia duodenalis genotype E in sheep from Brazil

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Comparison of selective and non selective cyclo-oxygenase 2 inhibitors in experimental colitis exacerbation: role of leukotriene B4 and superoxide dismutase

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Dosagem de metabólitos de glucocorticoides e progesterona em fezes de papagaio-verdadeiro (Amazona aestiva)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação da resposta imune sistêmica e compartimentalizada em pacientes portadoras de cãncer de ovário: sub-titulo / (se houver)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Influence of Fc gamma RIIIb polymorphism on its ability to cooperate with Fc gamma RIIa and CR3 in mediating the oxidative burst of human neutrophils

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Canine osteomyelitis caused by Leishmania sp

Leishmaniasis is a disease emerging or re-emerging worldwide distribution (Sousa, 2008), a major impact on public health. The canine visceral leishmaniasis is an infectious parasitic zoonosis of worldwide distribution (Troncarelli, 2009), caused by a flagellate protozoan called Leishmania chagasi (Costard, 2009). Osteomyelitis can develop when the parasite reaches the bone tissue of the host via blood or continuity of adjacent soft tissue infection (Baltenperger, 2004). The histopathology of the lesions has 100% specificity when viewing the amastigote form of the parasite (Feitosa et al., 2000). A dog breed poodle, female, five years, with chronic lameness four months ago was attended by a veterinary, proceeded to the general clinical examination, radiographic evaluation of the hindquarters and the laboratory tests of enzyme immunoassay (ELISA) and indirect immunofluorescence (RIFI) for Leishmania sp. On examination, besides the enlargement of lymph nodes, the animal showed pain on flexion and extension of hind limbs. In radiographic lytic bone lesions were observed in bilateral ischial board and greater trochanter of the femur, suggestive of osteomyelitis. In specific laboratory tests for diagnosis of leishmaniasis ELISA reagent and RIFI reagent 1:40. As recommended by the Ministry of Health, the animal was euthanized. No macroscopic findings were reported during the necropsy, usually associated with leishmaniasis. The ischium bone fragments were sent for histopathological examination. There was intense proliferation of mononuclear inflammatory cells, mainly macrophages and lymphocytes. Amastigotes of Leishmania sp, were identified in the cytoplasm of some macrophages and bone tissue. In endemic areas for canine leishmaniasis, dogs with a history of intermittent lameness, and radiographic lytic bone lesions suggestive of osteomyelitis should be directed to realization of the histopathology and serologic tests for the differential diagnosis of Leishmania sp. Even without evidence of cutaneous or visceral lesions, usually associated with this disease.