School of Nursing Class of 1997

Top Row: Shelly Adkins, Nikki Alexadner, Amy L. Ancona, Adem Arslani, Noel Baldwin, Lea Bell, Michelle Bellah, Nicole Bills, Sarah Boyle, Rebekah Brandstatter, Margitt Brigant, Matthew Brooks, Julie Campbell, Lea Clemmons

Row 2: Iracema M. Crawford, Amy Decker, Danielle Terry, Jennifer McGeown, Megan Lindsey Tvaska, Molly McIntyre, Sharon M. Hoover, Mary Beth Pohanka, Jennifer Nelson, Jennifer Carney, Katheryn E. Huffman, Toria Dial, Mary Dooley

Row 3: Pamela Earl, Stacy Ekelman, Jennfier Emery, Robert Farrell, Stephanie R. Faudel, Amy Fischer, Rochelle Fountain, Diane Fox

Row 4: Tina Garcia, Monica Gatica, Meredith Giles, Karla Giminez, Emily Goodsell, Barbara Gurd, Keren Kay Hahn, Beth Hosmer, Shana N. Howard, Cina Jackson-Hanner

Row 5: Kristy Jakubiak, Rebekah Johnson, Stephanie T. Johnson, Jennifer Jorissen, Richard W. Redman, Beverly Jones, Ada Sue Hinshaw, Nola Pender, Susan Boehm, Renee Kaplan, Angela Kendrick-Newing, Emily Kerschbaum, Donulae Knuckles

Row 6: Diane Kramer, Alyce Krause, Krista L. Kuczewski, Lori LaCrone, Melissa E. Lorencen, Sarah Lyons, Melissa Magante, Kathleen Mahon, Christy Mayes, Joseph Morris, Elizabeth Morrow, Tamala Myers, Michele Nextico

Row 7: Jacquelyn Nino, Denise Noto, Catherine Orser, Elizabeth Palad, Ann Peterson, Joshua Pietsch, Pati Putt, Lisa Reinhart, Jamie C. Renken, Amy Robbins, Ernest Saxton, Amy Schafer, Joelle Schroeder, Matthew Seiler

Row 8: Sarah Bellestri Shih, Kristen Sisson, Shalonda Smith, Kathleen Stewart, Jeannine Sutter, Jamie Swan, Arita Ann Sywenkyj, Julie Talbott, Diana Thorrez, Natasha Tokarz, Whitney Tonkin, Rea Tsatsanifos, Tina Urbanski

Row 9: Maricar Uy, Dana Van Singel, Tanya D. Venton, Christina Vitucci, Samuel Walsh, Susan Warren, Tiana Washington, Yvette White, Judy M. Wilson, Cerise Wotorson, Bella Yagolkovskaya, Karen Zalenko, Susan M. Zucal

School of Nursing Class of 2008

Top Row: Therese Adamowski, Anel Adamson, Michelle Ahleman, Brooke Babineau, Jennifer Ballough, Lisa Anne Beckman, Jennifer Bergeren, Tedra Boedigheimer, Mary Bonner, Genevieve Bott, Megan Bouwhuis, Mitchell Bradley, Rachel Brown, Katherine Bulson, Jennifer Calhoun, Carley Cebelak, Sarah Choinard

Row 2: Sarah Clevenger, Elizabeth Anne Conway, Erin Coughlin, Karie Curtis, Stephanie Curtis, Jodi Danhof, Rebecca Debri, Stacie Deleszek, Andrea Dehline, Amanda Devlin, Charlotte Dietrich, Angela Dodge, Elizabeth Dougherty, Ashley Doyle, Lindsay Driver, Nancy Duckworth, Kathy Dunnuck, Jennifer Dziadaio, Ellen English

Row 3: Kelly Esser, Amanda Fender, Lindsey Smith, Andrew Bradburn, Fallon Garfield Turner, Margaret Dembeck, Courtney Van Essen, Jessica paige Smith, Lauren Inouye, Jacqueline Dufek, Emily Klump, Amanda Jones, Tiffany Burrell, Deborah Mitchell, Emily Michel, Michelle Steen, Kirsten Thulin, Emily Hautamaki, Sheila Fender, Keith Ferguson

Row 4: Annie Fields, Jillian Fisher, Erin Flatley, Renee Forma, Aileen Franchi, Lindsey Freysinger, Sarah Fulgenzi, Beth Funnell, Andrea Galaviz, Lacey Garbo, Katherine Garcia, Lynn Garofalo

Row 5: Heather Gehrke, Nicole Genrich, Katie Giordano, Lindsey Glover, Andrea Godfrey, Jocelyn Gossman, Alana Greenberg, Julien Guttman, Sarah Halfmann, Kimberly Hanger, Allison Hanson, Stephanie Hecklin

Row 6: Geri Helminiak, Kristi Hershiser, Erin Hipp, Amanda Hoath, Tracy Hurlbutt, Nadya Indrei, Nisa Joorabchi, Katy Kerrigan, Layne Kiella, Jessica Kim, Samantha Klaiman, Jodi Knight, Laura Kovacic, Alicia Kreger

Row 7: Amanda Kretsch, Kimberly Kurzeja, Julie Lamonoff, Sarah Leirstein, Ashley Labb, Suzanne Loeb, Alessandra Lollini, Heather Loomis, Caroline Luke, Stephanie Maniquis, Elizabeth Mann, LaTasha Marable, Amanda McAdams, Mara McKinley

Row 8: Leah McLaughlin, Erin Migda, Scott Migut, Joane Nwoke, Lazarus Okammor, Brittany Pajewski, Judith Lynch-Sauer, Patricia Coleman-Burns, Bonnie Hagerty, Kathleen Potempa, Carol Loveland-Cherry, Carolyn Sampselle, Joanne Pohl, Sarah Pajtas, Maria Paneda, Jennifer Parker, Carol Peterson, Kimberley Peven, Rachel Poterek, Sarah Poucher

Row 9: Jannet Provost, Jessica Quigley, Nicole Rasmuson, Joanthan Reed, Sharon Reske, John Reves, Amy Riebe, Sara Riegner, Kelly Risicato, Christine Sabado, Stephanie Sargent, Jolene Schaefer, Erin Schroeder, Catherine Scott, Katherine See, Andrea Semaan, Jessica Shantz, Kathryn Sibbold, Kathleen Skendrovic, Aaron Smith, Elizabeth Stanton

Row 10: Mary Stewart, Ashley Strotbaum, Danielle Swartz, Janet Trost, Elizabeth Underwood, Lauren Underwood, Allison Vanhall, Brian Velker, Kristen Wells, Ryan Werblow, Jennifer Werden, David Westrin, Mallory Wiesen, Karen Wingrove, Amy Wright, Carrie Wright, Emily Wright, Minou Xie, Charles Zimmerman

School of Nursing Class of 2010

Top Row: Jocelyn Aden, Rachel Ades, Katrina Allen, Kayla Ashcraft, Kristie Baker, Amy Beaudoin, Heidi Beck, Beth Bentrum, Amber Blake, Lee Anna Braden, Dan Burd, Meaghan Burke, Mallory Calus, Irene Casillas, Veronica Cherney, Samantha Cholewa, Molly Conlen

Row 2: Wendy Corriveau, Meaghan Cotter, Kara DeGlopper, Colleen DeVoe, Hadley Dobbs, Kimberly Drury-Wallace, Hyesun Eitel, Sarah Elner, Douglas E. Elsey, Alyssa Fallot, Folake Famoye, Kristen Farr, Christine Fleck, Jennifer Fleming, Soncerae Gardner, Sarah Gilley, Joelle Gilmet

Row 3: Sara Goss, Amy Guffey, Taylor Griglak, Bridget Belvitch, Jaclyn Janks, Andrea Engles, Cassandra Smith, Lyndsy Brenner, Mallorie Patterson, Kristen Oltersdorf, Laura Kokx, Ross Zoet, Mary Osbach, Courtney Norman, Monica Habeck, Erica Hadley

Row 4: Amanda Hanert, Dayna Hasty, Nicole Heller, Ashley Howard, Robert Humburg, Andrew Humes, Grace Hwang, Amira Jackson, Kathryn Jipping, Shelly Johnson

Row 5: Lindsey Kappler, Jacqueline Klaiman, Sarah Knoedler, Jessica Kopicki, Kathryn Kovanda, Sarah Kovats, Emily Krogel, Kellie Kunkel, Kristin Lakatos, Chelsea Lazaroff, Bo Hwa Lee, Kelly Leja

Row 6: Kelli Littlejohn, Emilee Losey, Patricia Luna, Wilma MacKenzie, Matt Malkowski, Rachel Mallas, Emily McCallister, Diane McDonald, Dorian Michelson, Mary Miller, Nicole Miller, Kristen Muehlhauser

Row 7: Renee Muller, Katherine Mulvaney, Eugene Ngala, Christine Novotny, Colleen O'Connor, Cassey Parrish, Kimberly Peters, Kathleen Potempa, Bonnie Hagerty, Heather Poucher, Charles Reisdorf, Eric Retzbach, Sarah Rhem, Shannon Rice, Amy Roberts, Christie Schonsheck

Row 8: Franciska Schuett, Rhonda Schultz, Kristina Seidl, Teresa Semaan, Shelley Sibbold, Stacy Slater, Mary Snell, Mallory Stanton, Dennis Stevens, Miranda Stoddard, Tatiana Tafla, Priscilla Tang, Bethany Thelen, Jessica Thibert, Rebecca Thurk, Lauren Tormoehlen, Chinasa Uwandu

Row 9: Margaret van Buitenen, Stacey Victor, Jennifer Waag, Kirstyn Wade, Ariel Warren, Elizabeth White, Natalie Wierenga, Jessica Wihowski, Wendy Witkowski, Aliza Wolfe, DaShaunn Woolard, Ting Wan Yip, Alexander Young, Kellie Zenz, Kristen Ziulkowski, Jessica Zmierski

2001/2002 UM Women's Basketball Team

Back Row: head coach Sue Guevara, assistant head coach Angela Jackson, Tabitha Pool, BreAnne McPilamy, Katrina Mason, Jennifer Smith, LeeAnn Bies, Stephanie Gandy, Sierra Hauser-Price, assistant coach Eileen Shea-Hilliard, assistant coach Ron Mott,

director of basketball operations Molly Murray, trainer Roxann Dahl, Alayne Ingram, Heather Oesterle, Raina Goodlow, Susana Jara, manager Stacey Lerchenfeld, student trainer Beth Chase

University of Michigan Field Hockey Team, 2005

Back Row: head coach Nancy Cox, Kristen Tiner?, Kara Lentz, Heather Wiley, Beth Riley, Catherine Pickard, Jillianne Whitfield, Jeannie Goldfarb, Lori Hillman, assistant coach Patrick Cota

Middle Row: Paige Pickett, Ashley Lennington, Kerri DeVos, Nicole Lonsway, Mary Fox, Eleanor Martin, Michaela McDermott, assistant coach Tracey Fuchs

Front Row: Lucia Belassi, Erin Dallas, Sarah Wilite?, Lauren MacMillan, Katie Morris, Jill Civic?, Stephanie Hoyer

Executive sessions of the Senate Permanent Subcommittee on Investigations of the Committee on Government Operations.

Shipping list no.: 2003-0174-P (volumes 1-2), 2003-0176-P (volumes 3-4), 2003-0184-P (volume 5), 2004-0047-P (index).

Health benefits for retirees : employer-based plans /

"April 8, 1993."

Durable complete clinical responses in a phase I/II trial using an autologous melanoma cell/dendritic cell vaccine

Advanced metastatic melanoma is incurable by standard treatments, but occasionally responds to immunotherapy. Recent trials using dendritic cells (DC) as a cellular adjuvant have concentrated on defined peptides as the source of antigens, and rely on foreign proteins as a source of help to generate a cell-mediated immune response. This approach limits patient accrual, because currently defined, non-mutated epitopes are restricted by a small number of human leucocyte antigens. It also fails to take advantage of mutated epitopes peculiar to the patient's own tumour, and of CD4(+) T lymphocytes as potential effectors of anti-tumour immunity. We therefore sought to determine whether a fully autologous DC vaccine is feasible, and of therapeutic benefit. Patients with American Joint Cancer Committee stage IV melanoma were treated with a fully autologous immunotherapy consisting of monocyte-derived DC, matured after culture with irradiated tumour cells. Of 19 patients enrolled into the trial, sufficient tumour was available to make treatments for 17. Of these, 12 received a complete priming phase of six cycles of either 0.9X10(6) or 5X10(6) DC/intradermal injection, at 2-weekly intervals. Where possible, treatment continued with the lower dose at 6-weekly intervals. The remaining five patients could not complete priming, due to progressive disease. Three of the 12 patients who completed priming have durable complete responses (average duration 3 5 months +), three had partial responses, and the remaining six had progressive disease (WHO criteria). Disease regression was not correlated with dose or with the development of delayed type hypersensitivity responses to intradermal challenge with irradiated, autologous tumour. However, plasma S-100B levels prior to the commencement of treatment correlated with objective clinical response (P = 0.05) and survival (log rank P < 0.001). The treatment had minimal side-effects and was well tolerated by all patients. Mature, monocyte-derived DC preparations exposed to appropriate tumour antigen sources can be reliably produced for patients with advanced metastatic melanoma, and in a subset of those patients with lower volume disease their repeated administration results in durable complete responses.

The impact of rehabilitation support services on health-related quality of life for women with breast cancer

As the number of women surviving breast cancer increases, with implications for the health system, research into the physical and psychosocial sequelae of the cancer and its treatment is a priority. This research estimated self-reported health-related quality of life (HRQoL) associated with two rehabilitation interventions for breast cancer survivors, compared to a non-intervention group. Women were selected if they received an early home-based physiotherapy intervention (DAART, n = 36) or a group-based exercise and psychosocial intervention (STRETCH, n = 31). Questionnaires on HRQoL, using the Functional Assessment of Cancer Therapy - Breast Cancer plus Arm Morbidity module, were administered at pre-, post-intervention, 6- and 12-months post-diagnosis. Data on a non-intervention group (n = 208) were available 6- and 12-months post-diagnosis. Comparing pre/post-intervention measures, benefits were evident for functional well-being, including reductions in arm morbidity and upper-body disability for participants completing the DAART service at one-to-two months following diagnosis. In contrast, minimal changes were observed between pre/post-intervention measures for the STRETCH group at approximately 4-months post-diagnosis. Overall, mean HRQoL scores (adjusted for age, chemotherapy, hormone therapy, high blood pressure and occupation type) improved gradually across all groups from 6- to 12-months post-diagnosis, and no prominent differences were found. However, this obscured declining HRQoL scores for 20-40% of women at 12 months post-diagnosis, despite receiving supportive care services. Greater awareness and screening for adjustment problems among breast cancer survivors is required throughout the disease trajectory. Early physiotherapy after surgery has the potential for short-term functional, physical and overall HRQoL benefits.

A cost-effectiveness analysis of two rehabilitation support services for women with breast cancer

The purpose of this research was to estimate the cost-effectiveness of two rehabilitation interventions for breast cancer survivors, each compared to a population-based, non-intervention group (n = 208). The two services included an early home-based physiotherapy intervention (DAART, n = 36) and a group-based exercise and psychosocial intervention (STRETCH, n = 31). A societal perspective was taken and costs were included as those incurred by the health care system, the survivors and community. Health outcomes included: (a) 'rehabilitated cases' based on changes in health-related quality of life between 6 and 12 months post-diagnosis, using the Functional Assessment of Cancer Therapy - Breast Cancer plus Arm Morbidity (FACT-B+4) questionnaire, and (b) quality-adjusted life years (QALYs) using utility scores from the Subjective Health Estimation (SHE) scale. Data were collected using self-reported questionnaires, medical records and program budgets. A Monte-Carlo modelling approach was used to test for uncertainty in cost and outcome estimates. The proportion of rehabilitated cases was similar across the three groups. From a societal perspective compared with the non-intervention group, the DAART intervention appeared to be the most efficient option with an incremental cost of $1344 per QALY gained, whereas the incremental cost per QALY gained from the STRETCH program was $14,478. Both DAART and STRETCH are low-cost, low-technological health promoting programs representing excellent public health investments.

Double-strand break repair gene polymorphisms and risk of breast or ovarian cancer

Deficiencies in DNA repair have been hypothesized to increase cancer risk and excess cancer incidence is a feature of inherited diseases caused by defects in DNA damage recognition and repair. We investigated, using a case-control design, whether the double-strand break repair gene polymorphisms RAD51 5' untranslated region -135 G > C, XRCC2 R188H G > A, and XRCC3 T241M C > T were associated with risk of breast or ovarian cancer in Australian women. Sample sets included 1,456 breast cancer cases and 793 age-matched controls ages under 60 years of age, 549 incident ovarian cancer cases, and 335 controls of similar age distribution. For the total sample and the subsample of Caucasian women, there were no significant differences in genotype distribution between breast cancer cases and controls or between ovarian cancer cases and combined control groups. The crude odds ratios (OR) and 95% confidence intervals (95% CI) associated with the RAD51 GC/CC genotype frequency was OR, 1.10; 95% CI, 0.80-1.41 for breast cancer and OR, 1.22; 95% CI, 0.92-1.62 for ovarian cancer. Similarly, there were no increased risks associated with the XRCC2 GA/AA genotype (OR, 0.98; 95% CI, 0.76-1.26 for breast cancer and OR, 0.93; 95% CI, 0.69-1.25 for ovarian cancer) or the XRCC3 CT/TT genotype (OR, 0.92; 95% Cl, 0.77-1.10 for breast cancer and OR, 0.87; 95% CI, 0.71-1.08 for ovarian cancer). Results were little changed after adjustment for age and other measured risk factors. Although there was little statistical power to detect modest increases in risk for the homozygote variant genotypes, particularly for the rare RAD51 and XRCC2 variants, the data suggest that none of these variants play a major role in the etiology of breast or ovarian cancer.