[Portrait d'Alexandre Cromer, à mi-jambes, assis, les bras croisés] : [photographie] / Adolphe Legros

Ancien possesseur : Cromer, Gabriel (1873-1934)

[Paysage de bord de mer : habitations et plage] : [photographie] / Hippolyte Fizeau

Ancien possesseur : Jussieu, Adrien de (1797-1853)

[Paysage de bord de mer : falaises et plage] : [photographie] / Hippolyte Fizeau

Ancien possesseur : Jussieu, Adrien de (1797-1853)

[Toits de Paris, vus de chez H. Fizeau] : [photographie] / Hippolyte Fizeau

Ancien possesseur : Jussieu, Adrien de (1797-1853)

[Portrait de femme, à la robe à carreaux décolletée, à mi-corps, assise, de trois-quarts à gauche] : [photographie] / Pierre Ambroise Richebourg

Ancien possesseur : Gilles, Albert (1873-1959)

[Nu féminin allongé, de face] : [photographie] / Pierre Ambroise Richebourg

Référence bibliographique : cat. 236

President's Portrait

On Tuesday, February 10th, 1970, Chairman of the Board, D. Whiting Lathrop presented a portrait of Dr. Gibson to the University. The plaque reads: Dr. James A. Gibson First President and Vice Chancellor of Brock University by Ian Henderson Artist in Residence 1969-1970 Presented to the University by the Board of Governors February 1970 The portrait hung in Dr. Gibson's waiting room until the end of his presidency where it was relocated to H-Block in MacKenzie Chown.

Granite Unveiling

As part of the celebration of the 200th anniversary of Sir Isaac Brock's birth on October 6, 1969, a piece of granite from Isaac Brock's childhood home in Guernsey was unveiled along with a plaque commemorating the ties between the General, the University, and Guernsey. The granite had been donated by Sir William Arnold, Bailiff of Guernsey, two years prior and had been in the possession of the university since that time before it was unveiled. The granite block was integrated into a wall in the Thistle Complex. It has since been relocated and is now part of a wall in the Walker Complex. Pictured here from left to right are: Sir William Arnold, Mrs. Arnold, Dr. Gibson and Governor General Michener.

Development of a bovine adenovirus type 2-based gene delivery vector /

ABSTRACT Recombinant adenoviruses are currently under intense investigation as potential gene delivery and gene expression vectors with applications in human and veterinary medicine. As part of our efforts to develop a bovine adenovirus type 2 (BAV2) based vector system, the nucleotide sequence of BAV2 was determined. Sixty-six open reading frames (ORFs) were found with the potential to encode polypeptides that were at least 50 amino acid (aa) residue long. Thirty-one of the BAV2 polypeptide sequences were found to share homology to already identified adenovirus proteins. The arrangement of the genes revealed that the BAV2 genomic organization closely resembles that of well-characterized human adenoviruses. In the course of this study, continuous propagation of BAV2 over many generations in cell culture resulted in the isolation of a BAV2 spontaneous mutant in which the E3 region was deleted. Restriction enzyme, sequencing and PCR analyses produced concordant results that precisely located the deletion and revealed that its size was exactly 1299 bp. The E3-deleted virus was plaque-purified and further propagated in cell culture. It appeared that the replication of such a virus lacking a portion of the E3 region was not affected, at least in cell culture. Attempts to rescue a recombinant BAV2 virus with the bacterial kanamycin resistance gene in the E3 region yielded a candidate as verified with extensive Southern blotting and PCR analyses. Attempts to purify the recombinant virus were not successful, suggesting that such recombinant BAV2 was helper-dependent. Ten clones containing full-length BAV2 genomes in a pWE15 cosmid vector were constructed. The infectivity of these constructs was tested by using different transfection methods. The BAV2 genomic clones did appear to be infectious only after extended incubation period. This may be due to limitations of various transfection methods tested, or biological differences between virus- and E. co//-derived BAV2 DNA.