Avaliação do efeito osteoindutivo do PDGF-BB associado a diferentes carreadores na regeneração óssea em cavidades cirurgicamente criadas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação da influência do plasma rico em plaquetas, da terapia com laser em baixa intensidade ou da associação de ambos na cicatrização de defeitos de fenestração periodontal em ratos: estudo histoquímico e imunoistoquímico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeito da reposição com melatonina no processo de reparo após reimplante dentário em ratos pinealectomizados: análise histomorfométrica

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeito de treinamento de saltos verticais e do destreinamento sobre a expressão gênica de vias energéticas da musculatura esquelética de ratos Wistar induzidos à obesidade

Pós-graduação em Fisioterapia - FCT

Influência da obesidade induzida por dieta hiperlipídica saturada sobre o comportamento da via beta-adrenérgica miocárdica em ratos Wistar

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Protocolos de natação em modelos experimentais com ratos

Exercise physiology has attempted to reproduce the experimental exercise in the laboratory using mainly rats. The swimming exercise has emerged as one of the leading research in these type ergometers. Thus, this research consisted of a literature review addressing the key issues which involve the exercise of swimming in the model rats. Training of aerobic and anaerobic swimming, evaluation models and models of periodization were the topics suggested in this research. In several studies, models of aerobic and anaerobic training have been proposed with the aim of studying their effect on normal and abnormal physiological parameters. However, earlier studies lacked methods of analysis aiming to determine the exercise intensity in the animal model. For this reason, in the last decade, assessment models have been adapted for humans to animals, especially rats. The maximal lactate steady state (MLSS) and lactate minimum (LM) are among the various techniques used to measure the amount of effort produced by swimming exercise in rats. Thereafter, based on biochemical parameters such as lactate, swimming exercise in rats has become the highest-rated, ie, using as reference the anaerobic threshold (AT). In another aspect, an entirely new line of research has tried to understand and promising swimming training in a periodized and its effects on some biochemical parameters. But this is an area little researched so far. Thus, the experimental model of swimming has proved an important resource of exercise physiology. From this model, it becomes possible to study the exercise, especially swimming, in more accurate, based on invasive and incisive analysis of the rat

Dental mineralization and salivary activity are reduced in offspring of spontaneously hypertensive rats (SHR)

Several pathologies have been diagnosed in children of hypertensive mothers; however, some studies that evaluated the alterations in their oral health are not conclusive. This study analyzed the salivary gland activity and dental mineralization of offsprings of spontaneously hypertensive rats (SHR). Thirty-day-old SHR males and Wistar rats were studied. The salivary flow was evaluated by injection of pilocarpine, the protein concentration and salivary amylase activity, by the Lowry method and kinetic method at 405 nm, respectively. Enamel and dentin mineralization of the mandibular incisors was quantified with aid of the microhardness meter. The results were analyzed by the ANOVA or Student's t test (p<0.05). It was noticed that the salivary flow rate (0.026 mL/min/100 g ± 0.002) and salivary protein concentration (2.26 mg/mL ± 0.14) of SHR offspring were reduced compared to Wistar normotensive offspring (0.036 mL/min/100 g ± 0.003 and 2.91 mg/mL ± 0.27, respectively), yet there was no alteration in amylase activity (SHR: 242.4 U/mL ± 36.9; Wistar: 163.8 U/mL ± 14.1). Microhardness was lower both in enamel (255.8 KHN ± 2.6) and dentin (59.9 KHN ± 0.8) for the SHR teeth compared to the Wistar teeth (enamel: 328.7 KHN ± 3.3 and dentin: 67.1 KHN ± 1.0). These results suggest that the SHR offspring are more susceptible to development of pathologies impairing oral health, once they presented lesser flow and salivary protein concentration and lower dental mineralization.

Análise morfológica do músculo reto abdominal de ratas prenhas diabéticas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação da atividade eletromecânica uterina em ratas por biosusceptometria AC e eletromiografia

Pós-graduação em Biologia Geral e Aplicada - IBB

Efeitos da ciclosporina na lesão renal por isquemia-reperfusão em ratos: estudo em modelo experimental

Pós-graduação em Anestesiologia - FMB

Efeitos da doxicilina na hipertensão arterial induzida pela exposiçao ao chumbo: quantificação de pepídeos vasoativos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Influência da suplementação da ração com diferentes doses de vitamina D sobre a proteína de interação com a tiorredoxina (TXNIP) no coração e suas vias de sinalização

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Análise do exercício físico e eletroestimulção do músculo tibial cranial após neurorrafia término-lateral do nervo fibular em ratos

Pós-graduação em Bases Gerais da Cirurgia - FMB

Farmacocinética pré-clínica e avaliação toxicológica do novo composto α2-adrenérgico 3-(2-cloro-6-fluorobenzil)-imidazolidina-2,4-diona - PT-31 GIRSUPAN

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Delayed tooth replantation after treatment of necrotic periodontal ligament with citric acid

Objective: to evaluated the effect of treating root-adhered necrotic periodontal ligament (PDL) with citric acid on the healing process in delayed rat tooth replantation. Material and Methods: Forty Wistar rats, assigned to 4 groups (n=10), had their upper right incisor extracted and kept dry on a workbench. For Group I (control), the teeth were replanted after a 5 min extra-alveolar time. For the other groups, replantation was hydroxide-based paste and the teeth were replanted with no root surface treatment. In Group III, the teeth were immersed in citric acid (pH 1) for replanted. In Group IV, instead of the immersion, the roots were scrubbed with gauze soaked in citric acid and the teeth were replanted. The animals difference (p > 0.05) was found among the groups regarding the areas difference (p < 0.05) between the control group and Group IV regarding ankylosis. The control group showed the least replacement resorption percent means compared to the other groups (p < 0.05). The root structure was more affected by replacement resorption and ankylosis in Group IV statistically (p > 0.05). Conclusion: the treatment of root surface-adhered necrotic periodontal ligament with citric acid was not able to prevent the delayed rat tooth replantation.