893 resultados para Minimal Set


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A CIF é uma ferramenta universal desenvolvida pela OMS que permite a classificação de funcionalidade e incapacidade, através de uma visualização global do que condiciona o desempenho do indivíduo na concretização de atividades e na participação em ocupações. A ideologia da CIF e os seus componentes interrelacionam-se com a essência da TO, indo ao encontro dos modelos da profissão. As UCCI constituem uma atualidade em Portugal e o terapeuta ocupacional é um dos profissionais obrigatórios na equipa multidisciplinar destas unidades. Atendendo à relevância internacional da CIF, à sua ligação com a TO e à necessidade de tornar a CIF operacional na prática clínica diária dado que é uma ferramenta complexa e extensa, é objetivo deste estudo contribuir para a construção de um code set da CIF para terapeutas ocupacionais que exercem funções em UCCI, especificamente em UC, UMDR e ULDM. Para a concretização desta investigação, utilizou-se a técnica de Delphi, que envolveu duas rondas. Na primeira ronda foi possível contar com a participação de 37 terapeutas ocupacionais experientes na área, uma vez que exercem funções em UCCI, e na segunda ronda contou-se com a participação de 20 elementos. Obtiveram consenso na última ronda de Delphi um total de 96 categorias, constituindo esta listagem uma proposta de code set para UCCI. No que se refere às tipologias de unidades, 69 categorias obtiveram consenso em UC, 91 em UMDR e 41 em ULDM. Concluiu-se que a criação de code sets poderá constituir uma mais-valia em contexto de equipa multidisciplinar das UCCI, sendo uma forma de tornar a CIF operacional na prática clínica diária.

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Dissertação de Mestrado em Engenharia de Redes de Comunicação e Multimédia

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Trabalho Final de Mestrado para obtenção do grau de Mestre em Engenharia Mecânica com Especialização em Energia, Climatização e Refrigeração

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Interest in polyethylene and polypropylene bonding has increased in the last years. However, adhesive joints with adherends which are of low surface energy and which are chemically inert present several difficulties. Generally, their high degree of chemical resistance to solvents and dissimilar solubility parameters limit the usefulness of solvent bonding as a viable assembly technique. One successful approach to adhesive bonding of these materials involves proper selection of surface pre-treatment prior to bonding. With the correct pre-treatment it is possible to glue these materials with one or more of several adhesives required by the applications involved. A second approach is the use of adhesives without surface pre-treatment, such as hot melts, high tack pressure-sensitive adhesives, solvent-based specialty adhesives and, more recently, structural acrylic adhesives as such 3M DP-8005® and Loctite 3030®. In this paper, the shear strengths of two acrylic adhesives were evaluated using the lap shear test method ASTM D3163 and the block shear test method ASTM D4501. Two different industrial polyolefins (polyethylene and polypropylene) were used for adherends. However, the focus of this study was to measure the shear strength of polyethylene joints with acrylic adhesives. The effect of abrasion was also studied. Some test specimens were manually abraded using 180 and 320 grade abrasive paper. An additional goal of this work was to examine the effect of temperature and moisture on mechanical strength of adhesive joints.

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Compreender a funcionalidade de uma criança é um desafio persistente em contextos de saúde e educação. Na tentativa de superar esse desafio, em 2007, a Organização Mundial de Saúde desenvolveu a Classificação Internacional de Funcionalidade, Incapacidade e Saúde para Crianças e Jovens (CIF-CJ) como o primeiro sistema de classificação universal para documentar a saúde e funcionalidade da criança. Apesar de a CIF-CJ não ser um instrumento de avaliação e intervenção, tem, no entanto, a capacidade de servir de enquadramento para o desenvolvimento de ferramentas adaptadas às necessidades dos seus utilizadores. Considerando que no contexto escolar, a escrita manual encontra-se entre as atividades mais requeridas para a participação plena de uma criança, parece ser pertinente a definição de um conjunto de códigos destinados a caracterizar o perfil de funcionalidade de uma criança, no que se refere à escrita manual. O objetivo deste estudo foi, pois, o desenvolvimento de um conjunto preliminar de códigos baseado na CIF-CJ que possa vir a constituir um code set para a escrita manual. Dada a complexidade do tema e atendendo a que se pretende alcançar consenso entre os especialistas sobre quais as categorias da CIF-CJ que devem ser consideradas, optou-se pela utilização da técnica de Delphi. A escolha da metodologia seguiu a orientação dos procedimentos adotados pelo projeto Core Set CIF. De dezoito profissionais contactados, obtiveram-se respostas de sete terapeutas ocupacionais com experiência em pediatria, que participaram em todas as rondas. No total, três rondas de questionários foram realizadas para atingir um consenso, com um nível de concordância, previamente definido, de 70%. Deste estudo resultou um conjunto preliminar de códigos com 54 categorias da CIF-CJ (16 categorias de segundo nível, 14 categorias de terceiro nível e uma categoria de quarto nível), das quais 31 são categorias das funções do corpo, uma categoria das estruturas do corpo, 12 categorias de atividades e participação e 10 categorias de fatores ambientais. Este estudo é um primeiro passo para o desenvolvimento de um code set para a escrita manual baseado na CIF-CJ , sendo claramente necessário a realização de mais pesquisas no contexto do desenvolvimento e da validação deste code set.

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As empresas nacionais deparam-se com a necessidade de responder ao mercado com uma grande variedade de produtos, pequenas séries e prazos de entrega reduzidos. A competitividade das empresas num mercado global depende assim da sua eficiência, da sua flexibilidade, da qualidade dos seus produtos e de custos reduzidos. Para se atingirem estes objetivos é necessário desenvolverem-se estratégias e planos de ação que envolvem os equipamentos produtivos, incluindo: a criação de novos equipamentos complexos e mais fiáveis, alteração dos equipamentos existentes modernizando-os de forma a responderem às necessidades atuais e a aumentar a sua disponibilidade e produtividade; e implementação de políticas de manutenção mais assertiva e focada no objetivo de “zero avarias”, como é o caso da manutenção preditiva. Neste contexto, o objetivo principal deste trabalho consiste na previsão do instante temporal ótimo da manutenção de um equipamento industrial – um refinador da fábrica de Mangualde da empresa Sonae Industria, que se encontra em funcionamento contínuo 24 horas por dia, 365 dias por ano. Para o efeito são utilizadas medidas de sensores que monitorizam continuamente o estado do refinador. A principal operação de manutenção deste equipamento é a substituição de dois discos metálicos do seu principal componente – o desfibrador. Consequentemente, o sensor do refinador analisado com maior detalhe é o sensor que mede a distância entre os dois discos do desfibrador. Os modelos ARIMA consistem numa abordagem estatística avançada para previsão de séries temporais. Baseados na descrição da autocorrelação dos dados, estes modelos descrevem uma série temporal como função dos seus valores passados. Neste trabalho, a metodologia ARIMA é utilizada para determinar um modelo que efetua uma previsão dos valores futuros do sensor que mede a distância entre os dois discos do desfibrador, determinando-se assim o momento ótimo da sua substituição e evitando paragens forçadas de produção por ocorrência de uma falha por desgaste dos discos. Os resultados obtidos neste trabalho constituem uma contribuição científica importante para a área da manutenção preditiva e deteção de falhas em equipamentos industriais.

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We exhibit the construction of stable arc exchange systems from the stable laminations of hyperbolic diffeomorphisms. We prove a one-to-one correspondence between (i) Lipshitz conjugacy classes of C(1+H) stable arc exchange systems that are C(1+H) fixed points of renormalization and (ii) Lipshitz conjugacy classes of C(1+H) diffeomorphisms f with hyperbolic basic sets Lambda that admit an invariant measure absolutely continuous with respect to the Hausdorff measure on Lambda. Let HD(s)(Lambda) and HD(u)(Lambda) be, respectively, the Hausdorff dimension of the stable and unstable leaves intersected with the hyperbolic basic set L. If HD(u)(Lambda) = 1, then the Lipschitz conjugacy is, in fact, a C(1+H) conjugacy in (i) and (ii). We prove that if the stable arc exchange system is a C(1+HDs+alpha) fixed point of renormalization with bounded geometry, then the stable arc exchange system is smooth conjugate to an affine stable arc exchange system.

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Making the transition between plans and unexpected occurrences is something organizations are used to doing every day. However, not much is known about how actors cope with unanticipated events and how they accommodate them within predefined schedules. In this study, we draw on an inductive analysis of aspiring filmmakers’ film sets to elaborate on how they plan their shooting activities every day, only to adjust them when unforeseen complications arise. We discover that film crews anchor their expectations for the day based on a planned shooting schedule, yet they incorporate a built-in assumption that it will inevitably be disrupted. We argue that they resort to triage processes and “troubleshooting protocols” that help decipher incoming problems. Familiar problems are solved by making use of experience obtained from past situations, whereas unprecedented problems are solved through a tacit protocol used as a tool to quickly devise an appropriate game plan. This study contributes to the literature on sense-making and provides valuable information about the unexplored world of filmmaking.

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Phosphatase and tensin homologue (PTEN) protein belongs to the family of protein tyrosine phos-phatase. Mutations on the phosphatase and tensin homologue (PTEN) protein are highly observed in diverse types of human tumors, being mostly identified on the phosphatase domain of the protein. Although PTEN is a modular protein composed by a phosphatase domain and a C2 domain for mem-brane anchoring, this work aimed at developing a minimal version of PTEN´s phosphatase domain. The minimal version (Small Domain) comprises a 28 residue peptide, with the PTEN 8-mer catalytic peptide accommodated between a α-helix and β-turn as observed in PTEN native structure. Firstly, a de novo prediction of the Small Domain´s secondary structure was carried out by molecular modeling tools. The stability of the predicted structures were then evaluated by Molecular Dynamics. Automated molecular docking of PTEN natural substrate PIP3, its analogue (Inositol) and a PTEN inhibitor (L-tar-tare) were performed with the modeled structure, and PTEN used as a positive control. The gene en-coding for Small Domain was designed and cloned into an expression vector at N-terminal of Green Fluorescence Protein (GFP) encoding gene. The fusion protein was then expressed in Escherichia coli cells. Different expression conditions have been explored for the production of the fusion protein to minimize the formation of inclusion bodies.

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Promotions can make you happy if you get the “best” deal or miserable if you miss it. Previous research on this topic has shown that people favor products associated with a past miss to products associated with a future miss, and people in a maximizing mind-set, i.e. people who search for the best in different domains, feel more regret in a consumption domain. This research confirms that consumers prefer purchasing a product associated with a past miss (Experiments 1 and 2) and that regret levels are higher when participants come across the future miss, under the maximizing mind-set (Experiment 2). These studies add to the notion that information on regret might prompt people to make decisions towards a more optimistic outcome.

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Operative treatment of coronoid fracture often requires a large dissection of soft tissue, resulting in elbow stiffness and functional limitation. The authors present a minimal invasive, safe technique, useful in the case of isolated coronoid fracture associated with elbow dislocation. This technique does not require soft tissue dissection and allows an early unlimited resumption of sports activities.

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Immunotherapy, especially therapeutic vaccination, has a great deal of potential in the treatment of cancer and certain infectious diseases such as HIV (Allison et al., 2006; Fauci et al., 2008; Feldmann and Steinman, 2005). Numerous vaccine candidates have been tested in patients with a variety of tumor types and chronic viral diseases. Often, the best way to assess the clinical potential of these vaccines is to monitor the induced T cell response, and yet there are currently no standards for reporting these results. This letter is an effort to address this problem.

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There are only a few studies on the ontogeny and differentiation process of the hypothalamic supraoptic-paraventriculo-neurohypophysial neurosecretory system. In vitro neuron survival improves if cells are of embryonic origin; however, surviving hypothalamic neurons in culture were found to express small and minimal amounts of arginine-vasopressin (AVP) and oxytocin (OT), respectively. The aim of this study was to develop a primary neuronal culture design applicable to the study of magnocellular hypothalamic system functionality. For this purpose, a primary neuronal culture was set up after mechanical dissociation of sterile hypothalamic blocks from 17-day-old Sprague-Dawley rat embryos (E17) of both sexes. Isolated hypothalamic cells were cultured with supplemented (B27)-NeuroBasal medium containing an agent inhibiting non-neuron cell proliferation. The neurosecretory process was characterized by detecting AVP and OT secreted into the medium on different days of culture. Data indicate that spontaneous AVP and OT release occurred in a culture day-dependent fashion, being maximal on day 13 for AVP, and on day 10 for OT. Interestingly, brain-derived neurotrophic factor (BDNF) and Angiotensin II (A II) were able to positively modulate neuropeptide output. Furthermore, on day 17 of culture, non-specific (high-KCl) and specific (Angiotensin II) stimuli were able to significantly (P < 0.05) enhance the secretion of both neuropeptides over respective baselines. This study suggests that our experimental design is useful for the study of AVP- and OT-ergic neuron functionality and that BDNF and A II are positive modulators of embryonic hypothalamic cell development.

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Brock Men's Volleyball makes a play in this 1978 match.

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Considerable research has focused on the success of early intervention programs for children. However, minimal research has focused on the effect these programs have on the parents of targeted children. Many current early intervention programs champion family-focused and inclusive programming, but few have evaluated parent participation in early interventions and fewer still have evaluated the impact of these programs on beliefs and attitudes and parenting practices. Since parents will continue to play a key role in their child's developmental course long after early intervention programs end, it is vital to examine whether these programs empower parents to take action to make changes in the lives of their children. The goal of this study was to understand parental influences on the early development of literacy, and in particular how parental attitudes, beliefs and self efficacy impact parent and child engagement in early literacy intervention activities. A mixed method procedure using quantitative and qualitative strategies was employed. A quasi-experimental research design was used. The research sample, sixty parents who were part of naturally occurring community interventions in at- risk neighbourhoods in a south-western Ontario city participated in the quantitative phase. Largely individuals whose home language was other than English, these participants were divided amongst three early literacy intervention groups, a Prescriptive Interventionist type group, a Participatory Empowering type group and a drop-in parent- child neighbourhood Control group. Measures completed pre and post a six session literacy intervention, on all three literacy and evidence of change in parental empowerment. Parents in all three groups, on average, held beliefs about early literacy that were positive and that were compatible with current approaches to language development and emergent literacy. No significant change in early literacy beliefs and attitudes for pre to post intervention was found. Similarly, there was no significant difference between groups on empowerment scores, but there was a significant change post intervention in one group's empowerment score. There was a drop in the empowerment score for the Prescriptive Interventionist type group, suggesting a drop in empowerment level. The qualitative aspect of this study involved six in-depth interviews completed with a sub-set of the sixty research participants. Four similar themes emerged across the groups: learning takes place across time and place; participation is key; success is achieved by taking small steps; and learning occurs in multiple ways. The research findings have important implications for practitioners and policy makers who target at risk populations with early intervention programming and wish to sustain parental empowerment. Study results show the value parents place on early learning and point to the importance of including parents in the development and delivery of early intervention programs. groups, were analyzed for evidence of change in parental attitudes and beliefs about early literacy and evidence of change in parental empowerment. Parents in all three groups, on average, held beliefs about early literacy that were positive and that were compatible with current approaches to language development and emergent literacy. No significant change in early literacy beliefs and attitudes for pre to post intervention was found. Similarly, there was no significant difference between groups on empowerment scores, but there was a significant change post intervention in one group's empowerment score. There was a drop in the empowerment score for the Prescriptive Interventionist type group, suggesting a drop in empowerment level. The qualitative aspect of this study involved six in-depth interviews completed with a sub-set of the sixty research participants. Four similar themes emerged across the groups: learning takes place across time and place; participation is key; success is achieved by taking small steps; and learning occurs in multiple ways. The research findings have important implications for practitioners and policy makers who target at risk populations with early intervention programming and wish to sustain parental empowerment. Study results show the value parents place on early learning and point to the importance of including parents in the development and delivery of early intervention programs.