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To improve the understanding of the development of locomotor capacity in layer hens, we measured how female laying hen chicks (n=120) of four different strains (LSL-lite, Hyline Brown, Dekalb White, Lohmann Brown; 3 groups of 10 chicks per line) utilized the ground, the air, elevated horizontal (platforms and perches) and inclined surfaces (ramps and ladders) in an aviary until 9 weeks of age. We used infra-red video recordings to perform all-occurrences sampling of locomotive behavioural and perching events that occurred on the ground—where bedding material, food and water were provided, in the air, and on elevated horizontal and inclined surfaces within weekly 30-min sampling periods. Chicks preferred level ground during the first week of life compared to weeks 5–9 (P<0.0001) and performed 52% of all behavioural events in this section. Elevated surface use began at 2 weeks of age and increased over time (P=0.003), where most behaviour was performed in S2 (45% of all events). Chicks preferred horizontal to inclined surfaces, which were used from weeks 2–5 with maximum use occurring during weeks 2 and 3. Lohmann LSL chicks used the space above the ground most frequently (P=0.05) and performed more aerial ascent/descent behaviour than other lines (P<0.0001). Overall activity levels declined with age (P<0.0001). In summary layer chicks almost exclusively locomoted on the ground but utilized elevated horizontal surfaces (perch, first platform) as early as 2 weeks. These results provide information for improving space use in rearing aviaries by introducing lower perches, platforms and ramps/ladders to accommodate age-dependent locomotor abilities.

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El rey Nabis de Esparta es caracterizado por las fuentes literarias antiguas como un tirano al haber emprendido una serie de reformas radicales que, particularmente en sus contenidos sociales, atentaban contra el orden establecido y ponían en peligro la supremacía en el Peloponeso de una conservadora liga aquea sostenida en las clases propietarias y respaldada por las imparables legiones romanas. Es el propósito del presente artículo analizar las bases de esa monarquía "revolucionaria" de Nabis, así como el alcance, los objetivos y la fortuna final de sus medidas, que supusieron un intento de acomodarse a la realidad de los estados helenísticos sin renunciar por ello a las señas de identidad y al acervo cultural espartano. La finalidad última era reconquistar parte de su pasado esplendor militar y lograr un lugar digno, si no hegemónico, en el complejo e inestable tablero geopolítico peloponésico, pero la elite aquea no cesó hasta acallar toda reivindicación socioeconómica en la sociedad lacedemonia.

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Structural and functional complexities of the mammalian lung evolved to meet a unique set of challenges, namely, the provision of efficient delivery of inspired air to all lung units within a confined thoracic space, to build a large gas exchange surface associated with minimal barrier thickness and a microvascular network to accommodate the entire right ventricular cardiac output while withstanding cyclic mechanical stresses that increase several folds from rest to exercise. Intricate regulatory mechanisms at every level ensure that the dynamic capacities of ventilation, perfusion, diffusion, and chemical binding to hemoglobin are commensurate with usual metabolic demands and periodic extreme needs for activity and survival. This article reviews the structural design of mammalian and human lung, its functional challenges, limitations, and potential for adaptation. We discuss (i) the evolutionary origin of alveolar lungs and its advantages and compromises, (ii) structural determinants of alveolar gas exchange, including architecture of conducting bronchovascular trees that converge in gas exchange units, (iii) the challenges of matching ventilation, perfusion, and diffusion and tissue-erythrocyte and thoracopulmonary interactions. The notion of erythrocytes as an integral component of the gas exchanger is emphasized. We further discuss the signals, sources, and limits of structural plasticity of the lung in alveolar hypoxia and following a loss of lung units, and the promise and caveats of interventions aimed at augmenting endogenous adaptive responses. Our objective is to understand how individual components are matched at multiple levels to optimize organ function in the face of physiological demands or pathological constraints. © 2016 American Physiological Society. Compr Physiol 6:827-895, 2016.

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Regents purchased south ten acres for $3000 in 1890. In 1902 UM received seven acres of land to the north from Dexter M. Ferry; became Ferry Field. In 1904 brick wall constructed on three sides and in 1906 gate and ticket office at northeast corner added (gift of Mr. Ferry). Wooden stands to accommodate 400 put up in 1893; burned in 1895. Rebuilt to seat 800 with later additions to facililties. By 1914, 13,600 accommodated. New stadium built in 1927. Stamp on verso: Ivory Photo

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Made-up set; title supplied.

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Cases cited in footnotes.

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Regents purchased south ten acres for $3000 in 1890. In 1902 UM received seven acres of land to the north from Dexter M. Ferry; became Ferry Field. In 1904 brick wall constructed on three sides and in 1906 gate and ticket office at northeast corner added (gift of Mr. Ferry). Wooden stands to accommodate 400 put up in 1893; burned in 1895. Rebuilt to seat 800 with later additions to facililties. By 1914, 13,600 accommodated. New stadium built in 1927.

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Regents purchased south ten acres for $3000 in 1890. In 1902 UM received seven acres of land to the north from Dexter M. Ferry; became Ferry Field. In 1904 brick wall constructed on three sides and in 1906 gate and ticket office at northeast corner added (gift of Mr. Ferry). Wooden stands to accommodate 400 put up in 1893; burned in 1895. Rebuilt to seat 800 with later additions to facililties. By 1914, 13,600 accommodated. New stadium built in 1927.

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Regents purchased south ten acres for $3000 in 1890. In 1902 UM received seven acres of land to the north from Dexter M. Ferry; became Ferry Field. In 1904 brick wall constructed on three sides and in 1906 gate and ticket office at northeast corner added (gift of Mr. Ferry). Wooden stands to accommodate 400 put up in 1893; burned in 1895. Rebuilt to seat 800 with later additions to facililties. By 1914, 13,600 accommodated. New stadium built in 1927.

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Regents purchased south ten acres for $3000 in 1890. In 1902 UM received seven acres of land to the north from Dexter M. Ferry; became Ferry Field. In 1904 brick wall constructed on three sides and in 1906 gate and ticket office at northeast corner added (gift of Mr. Ferry). Wooden stands to accommodate 400 put up in 1893; burned in 1895. Rebuilt to seat 800 with later additions to facilties. By 1914, 13,600 accommodated. New stadium built in 1927.On image: Printed in Germany

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Regents purchased south ten acres for $3000 in 1890. In 1902 UM received seven acres of land to the north from Dexter M. Ferry; became Ferry Field. In 1904 brick wall constructed on three sides and in 1906 gate and ticket office at northeast corner added (gift of Mr. Ferry). Wooden stands to accommodate 400 put up in 1893; burned in 1895. Rebuilt to seat 800 with later additions to facililties. By 1914, 13,600 accommodated. New stadium built in 1927.

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Regents purchased south ten acres for $3000 in 1890. In 1902 UM received seven acres of land to the north from Dexter M. Ferry; became Ferry Field. In 1904 brick wall constructed on three sides and in 1906 gate and ticket office at northeast corner added (gift of Mr. Ferry). Wooden stands to accommodate 400 put up in 1893; burned in 1895. Rebuilt to seat 800 with later additions to facililties. By 1914, 13,600 accommodated. New stadium built in 1927.

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Thesis (Ph.D.)--University of Washington, 2016-06

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Thesis (Master's)--University of Washington, 2016-06

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The modelling of inpatient length of stay (LOS) has important implications in health care studies. Finite mixture distributions are usually used to model the heterogeneous LOS distribution, due to a certain proportion of patients sustaining-a longer stay. However, the morbidity data are collected from hospitals, observations clustered within the same hospital are often correlated. The generalized linear mixed model approach is adopted to accommodate the inherent correlation via unobservable random effects. An EM algorithm is developed to obtain residual maximum quasi-likelihood estimation. The proposed hierarchical mixture regression approach enables the identification and assessment of factors influencing the long-stay proportion and the LOS for the long-stay patient subgroup. A neonatal LOS data set is used for illustration, (C) 2003 Elsevier Science Ltd. All rights reserved.