999 resultados para Desenvolvimento da expressão oral


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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Pós-graduação em Odontologia - FOAR

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The present study compared the expression of cytokeratins CK6, CK16 and CK19 and pan-cytokeratin (PAN) in oral mucosa cells between smokers and nonsmokers in order to determine the stage of cell differentiation and to consequently infer proliferative activity and expressions indicative of a potential for malignant differentiation. Thirty smokers and 30 non-smokers seen at the clinics of FOSJC-UNESP were screened. Smears were obtained from the left lateral border of the tongue with a cytobrush and slides were processed for immunohistochemistry using the antibodies reported Conventional microscopy was used for qualitative analysis. The results were analyzed statistically by the Z test, Fisher's exact test and comparison of two proportions (plus-4 confidence interval method). The expression of CK6 (p=0.002), CK16 (p=0.003), CK19 (p=0.0001) and PAN (p=0.008) was higher in oral mucosa smears from smokers compared to non- smokers. ln conclusion, increased epithelial proliferation is observed in the oral mucosa of smokers as demonstrated by the increased expression of CK6 and CKJ6, and these cells present alterations in epithelial maturation

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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This paper emerges from our research and extension courses university, from our concerns with the initial and continuous training of teachers and the Childhood Education and the early years of elementary school. We had, as a main focus, presenting aspects of some of these referrals effected towards the creation of possibilities for the collective creation of conditions to nourish all those involved in due diligence with a set of knowledge necessary for making decisions and positions on it and in pedagogical practice. Of theoretical and methodological perspective based our research, teacher training processes should meet the expression of their practical actions in order to produce new knowledge relativized, understood based on the circumstances, the social subjects and the social places of those prepare and disseminate. This understanding was responsible for the methodological choices made for the proposition and development of our research, primarily the oral history. Finally, we conclude, among other things, that the uniqueness of what is done, thought and spoken in the world of school and therefore, the practice of educational research through the narrative is full of content for the projection of new shares in favor of improved processes of teaching and learning aimed the formation and activity of teachers and the humanization of adults and children.