The Annual of scientific discovery: or, Year-book of facts in science and art.

1860

The Annual of scientific discovery: or, Year-book of facts in science and art.

1861

The Annual of scientific discovery: or, Year-book of facts in science and art.

1850

Elevated Blood Pressure and Obesity in Childhood: A Cross-Sectional Evaluation of 4,609 Schoolchildren

Background: The incidence of obesity in children is increasing worldwide, primarily in urbanized, high-income countries, and hypertension development is a detrimental effect of this phenomenon. Objective: In this cross-sectional study, we evaluated the prevalence of excess weight and its association with high blood pressure (BP) in schoolchildren. Methods: Here 4,609 male and female children, aged 6 to 11 years, from 24 public and private schools in Maringa, Brazil, were evaluated. Nutritional status was assessed by body mass index (BMI) according to cutoff points adjusted for sex and age. Blood pressure (BP) levels above 90th percentile for gender, age and height percentile were considered elevated. Results: The prevalence of excess weight among the schoolchildren was 24.5%; 16.9% were overweight, and 7.6% were obese. Sex and socioeconomic characteristics were not associated with elevated BP. In all age groups, systolic and diastolic BP correlated with BMI and waist and hip measurements, but not with waist-hip ratio. The prevalence of elevated BP was 11.2% in eutrophic children, 20.6% in overweight children [odds ratio (OR), 1.99; 95% confidence interval (CI), 1.61-2.45], and 39.7% in obese children (OR, 5.4; 95% CI, 4.23-6.89). Conclusion: Obese and overweight children had a higher prevalence of elevated BP than normal-weight children. Our data confirm that the growing worldwide epidemic of excess weight and elevated BP in schoolchildren may also be ongoing in Brazil.

On propositionalization for knowledge discovery in relational databases

Propositionalization, Inductive Logic Programming, Multi-Relational Data Mining

Mass transfer effects on reactive separation processes - discovery of reactive arrheotropes

Membrane reactor, reactive membrane separation, arrheotrope, azeotrope, dusty gas model, esterification, residue curve map, distillation, kinetics, singular point, bifurcation

Clinical Differences between Subtypes of Atrial Fibrillation and Flutter: Cross-Sectional Registry of 407 Patients

Introduction:Atrial fibrillation and atrial flutter account for one third of hospitalizations due to arrhythmias, determining great social and economic impacts. In Brazil, data on hospital care of these patients is scarce.Objective:To investigate the arrhythmia subtype of atrial fibrillation and flutter patients in the emergency setting and compare the clinical profile, thromboembolic risk and anticoagulants use.Methods:Cross-sectional retrospective study, with data collection from medical records of every patient treated for atrial fibrillation and flutter in the emergency department of Instituto de Cardiologia do Rio Grande do Sul during the first trimester of 2012.Results:We included 407 patients (356 had atrial fibrillation and 51 had flutter). Patients with paroxysmal atrial fibrillation were in average 5 years younger than those with persistent atrial fibrillation. Compared to paroxysmal atrial fibrillation patients, those with persistent atrial fibrillation and flutter had larger atrial diameter (48.6 ± 7.2 vs. 47.2 ± 6.2 vs. 42.3 ± 6.4; p < 0.01) and lower left ventricular ejection fraction (66.8 ± 11 vs. 53.9 ± 17 vs. 57.4 ± 16; p < 0.01). The prevalence of stroke and heart failure was higher in persistent atrial fibrillation and flutter patients. Those with paroxysmal atrial fibrillation and flutter had higher prevalence of CHADS2 score of zero when compared to those with persistent atrial fibrillation (27.8% vs. 18% vs. 4.9%; p < 0.01). The prevalence of anticoagulation in patients with CHA2DS2-Vasc ≤ 2 was 40%.Conclusions:The population in our registry was similar in its comorbidities and demographic profile to those of North American and European registries. Despite the high thromboembolic risk, the use of anticoagulants was low, revealing difficulties for incorporating guideline recommendations. Public health strategies should be adopted in order to improve these rates.

Optimization of radial jets mixing in cross-flow of combustion chambers using computational fluid dynamics

Cross-Flow, Radial Jets Mixing, Temperature Homogenization, Optimization, Combustion Chamber, CFD

Lexico-grammatical variation in the use of REQUEST strategies in Indian and British "letters to the editor" : a cross-cultural pragmatic study

Magdeburg, Univ., Fak. für Geistes-, Sozial- und Erziehungswiss., Diss., 2009

Galectin-3: A Link between Myocardial and Arterial Stiffening in Patients with Acute Decompensated Heart Failure?

Abstract Background: Heart failure is accompanied by abnormalities in ventricular-vascular interaction due to increased myocardial and arterial stiffness. Galectin-3 is a recently discovered biomarker that plays an important role in myocardial and vascular fibrosis and heart failure progression. Objectives: The aim of this study was to determine whether galectin-3 is correlated with arterial stiffening markers and impaired ventricular-arterial coupling in decompensated heart failure patients. Methods: A total of 79 inpatients with acute decompensated heart failure were evaluated. Serum galectin-3 was determined at baseline, and during admission, transthoracic echocardiography and measurements of vascular indices by Doppler ultrasonography were performed. Results: Elevated pulse wave velocity and low arterial carotid distensibility are associated with heart failure in patients with preserved ejection fraction (p = 0.04, p = 0.009). Pulse wave velocity, carotid distensibility and Young’s modulus did not correlate with serum galectin-3 levels. Conversely, raised galectin-3 levels correlated with an increased ventricular-arterial coupling ratio (Ea/Elv) p = 0.047, OR = 1.9, 95% CI (1.0‑3.6). Increased galectin-3 levels were associated with lower rates of left ventricular pressure rise in early systole (dp/dt) (p=0.018) and raised pulmonary artery pressure (p = 0.046). High galectin-3 levels (p = 0.038, HR = 3.07) and arterial pulmonary pressure (p = 0.007, HR = 1.06) were found to be independent risk factors for all-cause mortality and readmissions. Conclusions: This study showed no significant correlation between serum galectin-3 levels and arterial stiffening markers. Instead, high galectin-3 levels predicted impaired ventricular-arterial coupling. Galectin-3 may be predictive of raised pulmonary artery pressures. Elevated galectin-3 levels correlate with severe systolic dysfunction and together with pulmonary hypertension are independent markers of outcome.

Cross-talk of protein kinase B (PKB/Akt) with the transcription factor NFAT and the Src kinase Fyn in T lymphocytes

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2010

Discovery and visualization of interesting patterns

Die Preise für Speicherplatz fallen stetig, da verwundert es nicht, dass Unternehmen riesige Datenmengen anhäufen und sammeln. Diese immensen Datenmengen müssen jedoch mit geeigneten Methoden analysiert werden, um für das Unternehmen überlebensnotwendige Muster zu identifizieren. Solche Muster können Probleme aber auch Chancen darstellen. In jedem Fall ist es von größter Bedeutung, rechtzeitig diese Muster zu entdecken, um zeitnah reagieren zu können. Um breite Nutzerschichten anzusprechen, müssen Analysemethoden ferner einfach zu bedienen sein, sofort Rückmeldungen liefern und intuitive Visualisierungen anbieten. Ich schlage in der vorliegenden Arbeit Methoden zur Visualisierung und Filterung von Assoziationsregeln basierend auf ihren zeitlichen Änderungen vor. Ich werde lingustische Terme (die durch Fuzzymengen modelliert werden) verwenden, um die Historien von Regelbewertungsmaßen zu charakterisieren und so eine Ordnung von relevanten Regeln zu generieren. Weiterhin werde ich die vorgeschlagenen Methoden auf weitereModellarten übertragen, die Software-Plattformvorstellen, die die Analysemethoden dem Nutzer zugänglich macht und schließlich empirische Auswertungen auf Echtdaten aus Unternehmenskooperationen vorstellen, die die Wirksamkeit meiner Vorschläge belegen.

Motor and cognitive development of selected Egyptian and German primary school aged children : a cross-cultural study

Magdeburg, Univ., Fak. für Humanwiss., Diss., 2013

Improving TCP Performance on CSMA/CA Connections

In IP networks, most of packets, that have been dropped, are recovered after the expiration of retransmission timeouts. These can result in unnecessary retransmissions and needless reduction of congestion window. An inappropriate retransmission timeout has a huge impact on TCP performance. In this paper we have proved that CSMA/CA mechanism can cause TCP retransmissions due to CSMA/CA effects. For this we have observed three wireless connections that use CSMA/CA: with good link quality, poor link quality and in presence of cross traffic. The measurements have been performed using real devices. Through tracking of each transmitted packet it is possible to analyze the relation between one-way delay and packet loss probability and the cumulative distribution of distances between peaks of OWDs. The distribution of OWDs and the distances between peaks of OWDs are the most important parameters of tuning TCP retransmission timeout on CSMA/CA networks. A new perspective through investigating the dynamical relation between one-way delay and packet loss ratio depending on the link quality to enhance the TCP performance has been provided.

Cross-frequency coupling tracks motor automization and execution in the human motor system

Magdeburg, Univ., Fak. für Naturwiss., Diss., 2014