Human TOP3: a single-copy gene encoding DNA topoisomerase III.

A human cDNA encoding a protein homologous to the Escherichia coli DNA topoisomerase I subfamily of enzymes has been identified through cloning and sequencing. Expressing the cloned human cDNA in yeast (delta)top1 cells lacking endogenous DNA topoisomerase I yielded an activity in cell extracts that specifically reduces the number of supercoils in a highly negatively supercoiled DNA. On the basis of these results, the human gene containing the cDNA sequence has been denoted TOP3, and the protein it encodes has been denoted DNA topoisomerase III. Screening of a panel of human-rodent somatic hybrids and fluorescence in situ hybridization of cloned TOP3 genomic DNA to metaphase chromosomes indicate that human TOP3 is a single-copy gene located at chromosome 17p11.2-12.

Interaction between diurnal variations of intraocular pressure, pachymetry, and corneal response to an air puff: Preliminary evidence

Diurnal changes in corneal geometry, pachymetry, and intraocular pressure (IOP) in a healthy eye were recorded. The deformation response to an air puff was simulated using 3 levels of corneal stiffness. The response was dependent on IOP and pachymetry and not only on the biomechanical properties of the cornea. Similarly, the maximum variability due to the diurnal changes in pachymetry and IOP in the corneal displacement generated by the air puff was found to reach 5%. Therefore, diurnal changes in IOP and corneal thickness were able to induce some variability in the air puff–based corneal deformation response. This potential variability should be considered when the biomechanical properties of the cornea are analyzed with air-puff devices.

Copy of Gov[erno]r Philips's additional instructions about settling some Palatine families in Nova Scotia: Copy Col. Dunbar's additional instruction about settling some Irish families in Nova Scotia : manuscript, [1730]

Copies of two documents, approved 20 Apr. 1730; instructions to Richard Philips state that a number of Protestant Irish and Palatine families have been granted land in Nova Scotia, to be surveyed by David Dunbar; and instructions to Dunbar to survey and lay out land for the families.

Calculus of variations. Supplementary notes and exercises to 1945-1946 notes, at New York University.

Reproduced from typewritten copy.

Aspects of the calculus of variations /

Reproduced from type-written copy.

Supplement number one, light machine operation. The training of women for war production.

"Designed to supplement the series of unit courses for beginners in machine shop practice."--Pref.

A vision of Giorgione; three variations on Venetian themes.

Bound in pale purple paper boards; printed paper labels on front cover and spine; pale purple endpapers. Dust jacket.

Calculus of variations and supplementary notes and exercises, 1945-1946.

Reproduced from type-written copy.

Invitation to contractors, information for contractors and forms of contract, bond and contractor's proposal for construction of station finish for a part of the ... rapid transit railroad ... Form finally adopted by the Commission ...

No. 36/37 & 50, sect. 1-3. Queensboro subway.--No. 39, sect. 2. Broadway - Fourth avenue (New Utrecht avenue) - No. 43, 4/38, see no. 4/38, 43.--No. 48, sect. 1-2. Seventh avenue - Lexington avenue.--No. 50. Queensboro subway (Hunters Point avenue station

Leçons de calcul différentiel et de calcul intégral, rédigées d'après les méthodes et les ouvrages publiés ou inédits de A. L. Cauchy. Tome IV., Ier fasc.: Calcul des variations.

Available on demand as hard copy or computer file from Cornell University Library.

Leçons sur le calcul des variations

Available on demand as hard copy or computer file from Cornell University Library.

Isabella; or, The fatal marriage. A tragedy. Altered from Southern [sic] Distinguishing also the variations of the theatre. As performed at the Theatre-Royal in Drury-Lane.

First published under title The fatal marriage; or, The innocent adultery.

Organizational, direct support, and general support maintenance repair parts and special tools list for test stand, automotive generator, alternator, starter, and associated equipment, model GASR-500 : part number 7458-2, 7458-4, NSN 4910-01-041-8161, 4910-00-767-0218.

"May 1987."

The New England historical and genealogical register.

Beginning in 1924, Proceedings are incorporated into the Apr. number.

The history of the martyrs epitomised : A cloud of witnesses, or, The sufferers mirrour : made up of the swanlike songs, and other choice passages of a great number of martyrs and confessors, to the end of the sixteenth century, in their treatises, speeches, letters, prayers, &c. ... the whole alphabetically disposed /

LC copy bound in one volume.