“Adrenergic receptors and monoamines in the brain and pancreatic islets of streptozotoein diabetic rats: Role in insulin secretion as a function of age”

I) To study the changes in the content of brain rrrorroamirres in streptozotocirr-irrduced tliabetes as a lirnction of age and to lirrd the role oliadrenal lrornroncs in diabetic state. 2) To assess the adrenergic receptor function in the brain stem ofstreptozotocin-induced diabetic rats ofdillerent ages. 3) To study the changes in the basal levels of second messenger cAMP in the brain stenr ofstreptozotocin-induced diabetic rats as a function of age. 4) To study the changes occurring in the content ofmorroamines and their metabolites in whole pancreas and isolated pancreatic islets of streptozotocin-diabetic rats as a function ofage and the effect of adrenal hormones. 5) To study the adrenergic receptors and basal levels of cAMP in isolated pancreatic islets in young and old streptozotoein-diabetic rats. 6) The in virro study of CAMP content in pancreatic islets of young and old rats and its ellect on glucose induced insulin secretion. 7) 'lhe in vitro study on the involvement of dopamine and corticosteroids in glucose induced insulin secretion in pancreatic islets as a function of age.

Dynamic characterization of olfactory receptors in the fruit fly Drosophila melanogaster

Temporal changes in odor concentration are vitally important to many animals orienting and navigating in their environment. How are such temporal changes detected? Within the scope of the present work an accurate stimulation and analysis system was developed to examine the dynamics of physiological properties of Drosophila melanogaster olfactory receptor organs. Subsequently a new method for delivering odor stimuli was tested and used to present the first dynamic characterization of olfactory receptors at the level of single neurons. Initially, recordings of the whole antenna were conducted while stimulating with different odors. The odor delivery system allowed the dynamic characterization of the whole fly antenna, including its sensilla and receptor neurons. Based on the obtained electroantennogram data a new odor delivery method called digital sequence method was developed. In addition the degree of accuracy was enhanced, initially using electroantennograms, and later recordings of odorant receptor cells at the single sensilla level. This work shows for the first time that different odors evoked different responses within one neuron depending on the chemical structure of the odor. The present work offers new insights into the dynamic properties of olfactory transduction in Drosophila melanogaster and describes time dependent parameters underlying these properties.

Effects of SB-205384, a positive modulator of (alfa)3-subunit-containing GABA-A receptors, on isolation-induced aggressions in male mice. 'Efectos del SB-205384, un modulador positivo de los receptores GABA-A que contienen la subunidad (alfa)3, sobre la agresi??n inducida por aislamiento en ratones machos'

Resumen tomado de la publicaci??n

"Identification and Diversity of Killer Cell Ig-Like Receptors in Aotus vociferans, a New World Monkey "

Previous BAC clone analysis of the Platyrrhini owl monkey KIRs have shown an unusual genetic structure in some loci. Therefore, cDNAs encoding KIR molecules from eleven Aotus vociferans monkeys were characterized here; tenputative KIR loci were found, some of which encoded atypical proteins such as KIR4DL and transcripts predicted to encode a D0+D1 configuration (AOTVOKIR2DL1*01v1) which appear to be unique in the Aotus genus. Furthermore, alternative splicing was found as a likely mechanism for producing activator receptors in A. vociferans species. KIR proteins from New World monkeys may be split into three new lineages according to domain by domain phylogenetic analysis. Although the A. vociferans KIR family displayed a high divergence among paralogous genes, individual loci were limited in their genetic polymorphism. Selection analysis showed that both constrained and rapid evolution may operate within the AvKIR family. The frequent alternative splicing (as a likely mechanism generating activator receptors), the presence of KIR4DL and KIR2DL1 (D0+D1) molecules and other data reported here suggest that the KIR family in Aotus has had a rapid evolution, independent from its Catarrhini counterparts.from its Catarrhini counterparts.

Gramática de uso del español : teoría y práctica : A1-B2 Marco de referencia europeo.

Resumen basado en el de la publicación

Cuestiones marginales de gramática : análisis teórico y propuesta didáctica para los niveles B2 y C1.

Memoria de máster (Universidad de Salamanca, 2006). Resumen basado en el de la publicación

??Viajamos? : B2.2

Incluye "Gu??a did??ctica del profesor" (23 p.)

La poblaci??n y movimientos migratorios : B2.2

Monogr??fico con el t??tulo: "Unidades did??cticas de lengua y cultura espa??olas ( I)"

Cartilla de comprensi??n lectora para nivel B2 (seg??n el Marco Com??n de Referencia) para aprendientes de E/LE en Colombia

Trabajo fin de m??ster (Universidad de Ja??n-FUNIBER, 2013)

Materiales para la clase de espa??ol como lengua extranjera 2013 : nivel B2

Resumen basado en el de la publicaci??n

Una historia de piratas : la transitividad verbal y el uso de los pronombres objeto : propuesta d??d??ctica comunicativa para la ense??anza en el nivel B2 de la clase de ELE

Resumen basado en el de la publicaci??n

Ellas tienen la palabra : poemas de escritoras para la interacci??n oral en la clase de ELE : material complementario para los niveles B2, C1 y C2 del MCER

Resumen basado en el de la publicaci??n

Propuesta curricular de la lengua de signos espa??ola : nivel usuario independiente : B2

Esta publicaci??n de la serie de propuestas curriculares para la ense??anza y el aprendizaje de la lengua de signos espa??ola recoge las especificaciones (objetivos, contenidos y orientaciones metodol??gicas) para el Nivel B2, que se corresponde con el hom??nimo de la escala del MCER. Con ella se describe, en l??nea de continuidad con las entregas anteriores (Niveles A1 y A2; y Nivel B1), lo que supone que los alumnos alcancen un nuevo estadio en la estructura del curr??culo de la lengua de signos espa??ola.

Euskararen B2 maila : Derrigorrezko irakaskuntzaren amaieran (DBH-4) : ISEI-IVEI 2005

Existe una versi??n en espa??ol, con el t??tulo "Nivel B2 de euskera : al finalizar la ense??anza obligatoria (4?? ESO) : ISEI-IVEI 2005"