Bliss, Nathaniel, 1622-1654, autographed letter signed to John Winthrop; Springfield, Mass., 1 side (2 pages), 1652 December 21

Correspondence regarding an illness Bliss was suffering; he writes that the medicines Winthrop had given him were ineffective and he has been suffering fits. The letter, which was finished in an unknown hand, reports further symptoms had developed, including headache and blindness, and requests Winthrop again send instructions for taking the medicine he originally sent Bliss, and any other medicine he would recommend.

Fuller, Robert, autographed letter signed to John Winthrop; Rehoboth, Mass., 1 side (2 pages), 1652 September 29

Correspondence seeking advice from Winthrop about an illness that afflicted his children's heads and caused hair loss, and his sister's case of worms.

Hovey, Daniel, 1642-1695, autographed letter signed to John Winthrop; Ipswich, Mass., 1 side (2 pages), 1656 August 13

Correspondence relaying the progress of Hovey's stomach ailment after he took medicine prescribed by Winthrop, and further symptoms he was suffering, including chest pains. Hovey asks Winthrop for advice on additional action he should take to ease his symptoms.

Montague, Abigale, autographed letter signed to John Winthrop; Hadley, Mass., 1 side (2 pages), 1663 July 19

Correspondence about her seven-year-old daughter, who was suffering from inflammation and discharge from her eye, in which Montague requests Winthrop's advice on whether sarsaparilla root or English barley boiled with herbs would be an effective treatment. Montague adds a postscript about her own health, writing she has a "thick rotten fleame rising out of my stomach" but no cough.

Pynchon, John, 1621-1703, autographed letter signed to John Winthrop; Springfield, Mass., 1 side (2 pages), 1663 July 24

Correspondence seeking Winthrop's advice regarding treatment of his daughter, who had been vomiting and suffering insomnia and dry mouth for several days

Sherman, John, 1613-1685, autographed letter signed to John Winthrop; Watertown, Mass., 1 side (3 pages), 1663 June 30

Correspondence describing a hernia Sherman was suffering, and asking for Winthrop's advice and a "little of [your] red powder."

Ward, John, 1606-1693, autographed letter signed to John Winthrop; Cotohit [sic], Mass., 1 side (2 pages), 1652 May 29

Correspondence requesting advice for treating occasional fits of pain and cold Ward was suffering.

Rabbinical manuscripts of Judah Monis, ca. 1700s

This leather-bound volume contains ten handwritten Hebrew texts presumably compiled by Judah Monis in the early 18th century. The pieces range from three to 150 pages on different sized leaves and appear to be in multiple hands. The last page of the volume has the struck-through inscription, "Judah Monis' Book" and accompanies a 44-page text. The texts are unattributed and undated, but have been identified as transcriptions of cabalistic writings and include a short biography of Isaac Luria (1533-1572) and extracts from the work of Luria, Hayyim ben Joseph Vital, Jacob ben Hayyim Zemah, Abraham ben Isaac of Granada, and Naphtali Bachrach. The transcriptions appear to be unattributed and undated.

William Blair Townsend letter and receipt books, 1743-1805, bulk 1744-1777

The collection consists of two volumes, which date from 1743 to 1805, spanning his whole career as a merchant. Volume one is a letter book containing Townsend's business correspondence from November 23, 1743 to December 12, 1774. Most of the letters were written to American (many in North Carolina) and British (predominately in London) merchants. His earliest letters document his efforts to establish himself as a trader. Over time his letters turn to illustrate the common problems faced by many merchants: damaged goods, overpriced goods, embargos, and high freight costs. Particularly enlightening are his comments on the challenges of doing business throughout the French and Indian War and the years leading up to the American Revolution. He most frequently corresponded with London merchants Champion & Hayley, Lane & Booth, Lane Son & Fraser, Harrison & Ansley, and Leeds merchant Samuel Elam. In addition he frequently corresponded with Eliakim Palmer, colonial agent and merchant in London, as well as Dr. Walley Chauncy of North Carolina. He dealt in a wide variety of goods including molasses, rum, tar, medicines, pitch, saddles, tallow, hides, skins, pickled beef and pork, and wine. The letters also document Townsend's involvement in the slave trade through his occasional purchases of slaves.

Student lectures notes on chemistry and materia medica, and medical recipes, of Lyman Spalding, 1795-1799 (inclusive)

Contains notes taken by Harvard student Lyman Spalding during eleven chemistry lectures delivered by Harvard Professor Aaron Dexter (1750-1829) in the fall of 1795 and recipes prepared and used by Spalding in his medical practice in 1797. The recipes include elixir vitriol, containing liquor, Jamaica pepper, cinnamon, and ginger, and an electuary for a cough, containing oxymel squills (sea onion in honey), licorice, antimonium tartaricum potash (a compound of the chemical element antimony and a potassium-containing salt), and opium. The volume also contains writings about chemistry by Spalding, some of which appear transcribed from published sources, in undated entries, and a diary entry from 1799 regarding an experiment with water.

Student notes from medical lectures by Benjamin Rush, undated

The volumes contain student notes on a course of medical lectures given by Dr. Benjamin Rush (1746-1813) while he was Professor of the Institutes of Medicine and Clinical Practice at the University of Pennsylvania Medical School, likely in circa 1800-1813. The notes indicate Rush often referenced the works or teachings of contemporaries such as Scottish physicians William Cullen, John Brown, John Gregory, and Robert Whytt, and Dutch physician Herman Boerhaave. He frequently included anecdotes and case histories of his own patients, as well as those of other doctors, to illustrate his lecture topics. He also advised students to take notes on the lectures after they ended to allow them to focus on what they were hearing. Volume 1 includes notes on: physician conduct during visits to patients; human and animal physiology; voice and speech; the nervous system; the five senses; and faculties of the mind. Volume 2 includes notes on: food, the sources of appetite and thirst, and digestion; the lymphatic system; secretions; excretions; theories of nutrition; differences in the minds and bodies of women and men; reproduction; pathology; a table outlining the stages of disease production; “disease and the origin of moral and natural evil”; contagions; the role of food, drink, and clothing in producing disease; worms; hereditary diseases; predisposition to diseases; proximate causes of diseases; and pulmonary conditions. Volume 3 includes notes on: the pulse; therapeutics, such as emetics, sedatives, and digitalis, and treatment of various illnesses like pulmonary consumption, kidney disease, palsy, and rheumatism; diagnosis and prognosis of fever; treatment of intermitting fever; and epidemics including plague, smallpox, and yellow fever, with an emphasis on the yellow fever outbreaks in Philadelphia in 1793 and 1797.

Newton, Massachusetts, 1831 (Raster Image)

This layer is a georeferenced raster image of the historic paper map entitled: Map of the town of Newton, Mass., surveyed by E.F. Woodward & W.F. Ward. It was published by Annin, Smith, & Co.'s Lithogy. in Nov. 1831. Scale [ca. 1:20,660]. The image inside the map neatline is georeferenced to the surface of the earth and fit to the Massachusetts State Plane Coordinate System, Mainland Zone (in Feet) (Fipszone 2001). All map collar and inset information is also available as part of the raster image, including any inset maps, profiles, statistical tables, directories, text, illustrations, or other information associated with the principal map. This map shows features such as roads, railroads, drainage, public buildings, schools, churches, cemeteries, industry locations (e.g. mills, factories, mines, etc.), private buildings with names of property owners, town boundaries and more. The map shows town boundaries as of 1831 and thus covers also portions of modern day Waltham and Boston. Manuscript annotations on the map show approximate locations of current town boundaries. Relief is shown by hachures. This layer is part of a selection of digitally scanned and georeferenced historic maps of Massachusetts from the Harvard Map Collection. These maps typically portray both natural and manmade features. The selection represents a range of regions, originators, ground condition dates (1755-1922), scales, and purposes. The digitized selection includes maps of: the state, Massachusetts counties, town surveys, coastal features, real property, parks, cemeteries, railroads, roads, public works projects, etc.

Fossil and Nonfossil Sources of Organic and Elemental Carbon Aerosols in the Outflow from Northeast China

Source quantification of carbonaceous aerosols in the Chinese outflow regions still remains uncertain despite their high mass concentrations. Here, we unambiguously quantified fossil and nonfossil contributions to elemental carbon (EC) and organic carbon (OC) of total suspended particles (TSP) from a regional receptor site in the outflow of Northeast China using radiocarbon measurement. OC and EC concentrations were lower in summer, representing mainly marine air, than in other seasons, when air masses mostly traveled over continental regions in Mongolia and northeast China. The annual-mean contribution from fossil-fuel combustion to EC was 76 ± 11% (0.1−1.3 μg m−3). The remaining 24 ± 11% (0.03−0.42 μg m−3) was attributed to biomass burning, with slightly higher contribution in the cold period (∼31%) compared to the warm period (∼21%) because of enhanced emissions from regional biomass combustion sources in China. OC was generally dominated by nonfossil sources, with an annual average of 66 ± 11% (0.5−2.8 μg m−3), approximately half of which was apportioned to primary biomass burning sources (34 ± 6%). In winter, OC almost equally originated from primary OC (POC) emissions and secondary OC (SOC) formation from fossil fuel and biomass-burning sources. In contrast, summertime OC was dominated by primary biogenic emissions as well as secondary production from biogenic and biomass-burning sources, but fossil-derived SOC was the smallest contributor. Distinction of POC and SOC was performed using primary POC-to-EC emission ratios separated for fossil and nonfossil emissions.

Sources and seasonality of polycyclic aromatic hydrocarbons transported to Alert, Canadian Arctic

A probabilistic function (integrated source contribution function, ISCF) based on backward air mass trajectory calculation was developed to track sources and atmospheric pathways of polycyclic aromatic hydrocarbons (PAHs) to the Canadian High Arctic station of Alert. In addition to the movement of air masses, the emission intensities at the sources and the major processes of partition, indirect photolysis, and deposition occurring on the way to the Arctic were incorporated into the ISCF. The predicted temporal trend of PAHs at Alert was validated by measured PAH concentrations throughout 2004. The PAH levels in the summer are orders of magnitude lower than those in the winter and spring when long-range atmospheric transport events occur more frequently. PAHs observed at Alert are mostly from East Asia (including Russia Far East), North Europe (including European Russia), and North America. These sources account for 25, 45, and 27% of PAHs atmospheric level at Alert, respectively. Source regions and transport pathways contributing to the PAHs contamination in the Canadian High Arctic vary seasonally. In the winter, Russia and Europe are the major sources. PAHs from these sources travel eastward and turn to the north at approximately 120°E before reaching Alert, in conjunction with the well- known Arctic haze events. In the spring, PAHs from Russia and Europe first migrate to the west and then turn to the north at 60°W toward Alert. The majority of PAHs in the summer are from northern Canada where they are carried to Alert via low- level transport pathways. In the fall, 70% of PAHs arriving at Alert are delivered from North American sources.