992 resultados para Third language


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Humanist writers were multifaceted and thcir writings eclectic, delving into a wide range of fields of enquiry Many issues wcre raised and addressed, pursued ur abandoned, uftcn unsystematically. ‘[his hetcrogeneity has frequently lcd tu the neglect of specific facets of authurs who have gained renuwn in uthcr fzelds. ‘[his 1 believe tu be the case fur Richard Mulcaster and Juan Luis Vives, whuse contribution tu language Éhcory has been eclipsed by their rclatively mudem views un educatiun. ‘[heir views un language merit mure attention, if not fur their originality as such, at least fur te testimony they pruvide uf a periud in transition. ‘[he work uf these authors show 1mw views un language evolved thruughout te periud mié convey a sense uf its dynamic character. Profoundly cunservative attitudes coexist with progressive unes and, tliough ruoted in the past, thcy strain tuwards a new vision uf the nature and functioning uf language in human sucicty.

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Although the majority of English language teachers worldwide are non-native English speakers, no research was conducted on these teachers until recently. After the pioneering work of Robert Phillipson in 1992 and Peter Medgyes in 1994, nearly a decade had to elapse for more research to emerge on the issues relating to non-native English teachers. The publication in 1999 of George Braine's book Nonnative educators in English language teaching appears to have encouraged a number of graduate students and scholars to research this issue, with topics ranging from teachers' perceptions of their own identity to students' views and aspects of teacher education. This article compiles, classifies, and examines research conducted in the last two decades on this topic, placing a special emphasis on World Englishes concerns, methods of investigation, and areas in need of further attention.

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Signal transduction systems mediate the response and adaptation of organisms to environmental changes. In prokaryotes, this signal transduction is often done through Two Component Systems (TCS). These TCS are phosphotransfer protein cascades, and in their prototypical form they are composed by a kinase that senses the environmental signals (SK) and by a response regulator (RR) that regulates the cellular response. This basic motif can be modified by the addition of a third protein that interacts either with the SK or the RR in a way that could change the dynamic response of the TCS module. In this work we aim at understanding the effect of such an additional protein (which we call ‘‘third component’’) on the functional properties of a prototypical TCS. To do so we build mathematical models of TCS with alternative designs for their interaction with that third component. These mathematical models are analyzed in order to identify the differences in dynamic behavior inherent to each design, with respect to functionally relevant properties such as sensitivity to changes in either the parameter values or the molecular concentrations, temporal responsiveness, possibility of multiple steady states, or stochastic fluctuations in the system. The differences are then correlated to the physiological requirements that impinge on the functioning of the TCS. This analysis sheds light on both, the dynamic behavior of synthetically designed TCS, and the conditions under which natural selection might favor each of the designs. We find that a third component that modulates SK activity increases the parameter space where a bistable response of the TCS module to signals is possible, if SK is monofunctional, but decreases it when the SK is bifunctional. The presence of a third component that modulates RR activity decreases the parameter space where a bistable response of the TCS module to signals is possible.