933 resultados para Sphere of influence


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Zinc plays a very important role in animal and human metabolism. Nowadays, it is one of the most extensively studied trace element, since its sphere of action has been demonstrated to be very broad. From the biochemical standpoint, it controls more than 300 different enzymes, many of them involved with intermediary metabolism, DNA and RNA synthesis, gene expression, and immunocompetence. It also plays a significant role in hormonal homeostasis, since it can interact with almost all hormones. Zn2+ is closely related to the thyroid and steroid hormones, insulin, parathormone, and pituitary hormones, particularly prolactin (PRL). Zn2+ can inhibit PRL secretion within a range of physiologically and pharmacologically relevant concentrations. This property has raised the possibility of clinical applications of zinc. In this article, we review the Literature on the subject in an attempt to provide a comprehensible general view.

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Reactions of [WC1(CO)(3)(bipy)(HgCl)], [bipy = 2,2 -bipyridine], with thioureas were performed giving compounds of the type [WCl(CO)(3)(bipy)(HgCl)L], [L = thiourea (tu); N-methylthiourea (mtu); N,N-dimethyithiourea (dmtu)] in which the coordination sphere of the tungsten atom remained unchanged. The coordination of the thioureas to mercury atom was proved to occur in accord to infrared spectra, through the sulphur atom.

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Persistent cough leads individuals to seek for medical assistance. Clinical investigation, however, may not reveal any alteration within the clinic's sphere of action. Often enough, some professionals treat the symptom as a disease, introducing several medicines, unsuccessfully. The author's experience, as an otolaryngologist, allows to state that many of these professionals ignore the upper aerodigestive tract as a cough-generator site. The present work discusses the alterations on the mentioned tract, which may provoke the cough reflex, reviewing, initially, the cough mechanism and the localization of the specific receptors. Cough is produce by stimulus at the receptor level or far from it. In upper and lower parts of the aerodigestive tract secretions may run to several directions. Secretion from the paranasal sinus is a frequent cause of cough. Acute sinusitis may occur insidiously bringing about the chronification of the inflammation with cough being the only great apparent symptom. Nasal and dental alterations favor sinusal infection. Signs and symptoms, even if minimum, may be detected through an accurate anamnesis. Nasal allergy, laryngitis, post nasal dripping and septal deviation may also produce cough. The ORL examination is, therefore, imperative, and no radiologic examination can substitute for it. An inadequate treatment, particularly of the sinusitis, may bring about a worsening and extension of the initial condition.

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Includes bibliography

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The question that leads this article is What is this virtual space in the on-line mathematics education process? We focus on the question of the real and virtual as issues taken as components of cyberspace. We investigate these notions in the history of philosophy, looking to Granger to find their meaning, to enable us to understand them and fit them into the sphere of Mathematics Education. This theoretical-philosophical article, then, claims that the virtuality of cyberspace is supported by the computer screen, built by the unification of the sciences (mathematics), technology and its applications. Software and the actions taken by Internet users update the capability of these programs in a variety of characteristics and possibilities such as space-time flow interconnections as well as during the mathematics education process.

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Includes bibliography

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With the evolution of the organizations theory, new management practices have transformed the institutions. The improvement of these management practices in cultural unities (UCs) is constant, and interacts in the international axis, since each unity increasingly communicate with other. As a reflection of organizational administrative practices, UCs had developed and assumed the organizational theories to make easy a framework for effective management practices. Comprehending the importance of the studies on UCs requires both a new approach of existing public politics for this field, and the recognition of the Information Science knowledge on area. In this way, it was planned to develop a model constituting a tool for managers in these institutions through the experience of laboratory works carried out with researchers from the European community. Libraries and museums are institutions that operate in the social process of their communities and the archives establish their structural spaces in parallel with the political, economic and social environments of the communities, translate the society and its organic sphere of informational performance. The information transposes a cyclical and essential role for the arrangement of the effective and necessary record to the organizational process and the institutional growth. Studies of this nature contribute to value a economy based on knowledge, and its production emphasizes the human capital that permeates the condition of the information in support for the development of communities and the growth of the organizational environment in political, social and cultural spheres.

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When dealing with spatio-temporal simulations of load growth inside a service zone, one of the most important problems faced by a Distribution Utility is how to represent the different relationships among different areas. A new load in a certain part of the city could modify the load growth in other parts of the city, even outside of its radius of influence. These interactions are called Urban Dynamics. This work aims to discuss how to implement Urban Dynamics considerations into the spatial electric load forecasting simulations using multi-agent simulations. To explain the approach, three examples are introduced, including the effect of an attraction load, the effect of a repulsive load, and the effect of several attraction/repulsive loads at the same time when considering the natural load growth. © 2012 IEEE.

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Includes bibliography

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Pós-graduação em Filosofia - FFC

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Pós-graduação em Ciências Sociais - FFC

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Pós-graduação em Ciências Sociais - FFC

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)