996 resultados para RE-WETTING AGENT


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The Iowa Department of Corrections (DOC) and the Department of Human Rights, Division of Criminal and Juvenile Justice Planning (CJJP) entered into a contract for services from January 2, 2007 to June 30, 2008 for the purposes of assisting in the evaluation component for the two-year Prison Re-Entry Initiative (PRI) grand awarded to the DOC by the U.S. Office of Justice Programs. The PRI grant period ran from July 2006 through June 2008 and included two primary components. First, all PRI participants returning to Polk County would participate in a Lifeskills curriculum offered through the Des Moines Area Community College (DMACC) at four Iowa prison institutions located at Mitchellville, Newton, Fort Dodge and Rockwell City. Second, all PRI participants returning to Polk County would be referred to The Directors Council (TDC) for cmmunity-based wrap-around services.

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The Iowa Department of Corrections (DOC) and the Department of Human Rights, Division of Criminal and Juvenile Justice Planning (CJJP) entered into a contract for services from September 12, 2007 to June 30, 2009 for the purposes of assisting in the evaluation component for the two-year Iowa Prisoner Re-Entry Initiative (PRI) Rural Service Delivery Model. This contract was extended to November 2009. The Rural PRI grant period ran from July 1, 2007 to June 30, 2009 and was extended to November 30, 2009. The purpose of the program was to improve community safety by providing pre-release services and successful transition planning and aftercare services to offenders released from state institutions to the Second Judicial District Department of Correctional Services. Participants included all offenders released to the Second Judicial District during the grant period.

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Community-acquired pneumonia (CAP) is a major cause of death in developing countries and of morbidity in developed countries. The objective of the study was to define the causative agents among children hospitalized for CAP defined by WHO guidelines and to correlate etiology with clinical severity and surrogate markers. Investigations included an extensive etiological workup. A potential causative agent was detected in 86% of the 99 enrolled patients, with evidence of bacterial (53%), viral (67%), and mixed (33%) infections. Streptococcus pneumoniae was accounted for in 46% of CAP. Dehydration was the only clinical sign associated with bacterial pneumonia. CRP and PCT were significantly higher in bacterial infections. Increasing the number of diagnostic tests identifies potential causes of CAP in up to 86% of children, indicating a high prevalence of viruses and frequent co-infections. The high proportion of pneumococcal infections re-emphasizes the importance of pneumococcal immunization.

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Los proyectos forman la identidad de las personas, y las personas construyen la identidad de los proyectos. El objetivo de este artículo, es describir la trayectoria del practicum dentro de los estudios de educación social de la Universidad de Barcelona a partir de identificar los elementos que han impulsado su construcción y reconstrucción. La historia de este practicum se caracteriza por las diferentes decisiones que se han tomado, y los permanentes cuestionamientos de éstas, en los casi veinte años de funcionamiento. Pero, no sólo las decisiones tomadas han supuesto un avance o evolución sino también la forma en que éstas se han tomado. Esta evolución va de la mano de tres planes de estudios que han supuesto la oportunidad de revisar y reflexionar qué era el practicum y qué debería llegar a ser. El presente, pasado y futuro del practicum ha sido un proceso de reconstrucción desde la reflexión y evaluación de los agentes implicados. No ha sido una trayectoria en solitario, sino que ha supuesto un proceso colectivo que ha configurado los diferentes espacios formativos y la función docente de los agentes implicados. El camino que hemos andado, y trazado, nos ha permitido evolucionar en los planteamientos, aprender de la experiencia compartida y construir nuestra identidad. Esta evolución permite configurar las prácticas dentro del Grado de Educación Social a partir del modelo de partenariado de reciprocidad, modelo que se ha de consolidar y sistematizar para seguir innovando colectivamente.

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We have developed a thrombin-sensitive polymeric photosensitizer prodrug (T-PS) to selectively image and eradicate inflammatory lesions in rheumatoid arthritis (RA). Thrombin is a serine protease up-regulated in synovial tissues of rheumatoid arthritis (RA) patients. T-PS consists of a polymeric backbone, to which multiple photosensitizer (PS) units are tethered via short thrombin-cleavable peptide linkers. Fluorescence emission and phototoxicity of the prodrug are efficiently quenched due to the interaction of neighboring photosensitizer units. The prodrug is passively delivered to the inflammation site via the enhanced permeability and retention (EPR) effect. Subsequent site-selective proteolytic cleavage of the peptide linkers restores its photoactivity by increasing the mutual distance between PS. Whole animal imaging in murine collagen-induced arthritis, an experimental model of RA revealed a dose-dependent fluorescence increase in arthritic paws after systemic prodrug injection. In addition, administration of T-PS resulted in much higher fluorescence selectivity for arthritic joints as compared to the free PS. Irradiation of the arthritic joints induced light dose dependent phototoxic effects such as apoptosis, vascular damage and local hemorrhage. Long-term observations showed complete regression of the latter. Irradiated non-arthritic tissues or non-irradiated arthritic tissues showed no histological effects after photodynamic therapy with T-PS. This illustrates that T-PS can localize inflammatory lesions with excellent selectivity and induce apoptosis and vascular shut down after irradiation.

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Les réformes du système de la santé, introduisant des objectifs d'efficience et de rentabilité inspirés de la doctrine de la Nouvelle gouvernance publique (NGOP), impactent l'organisation des hôpitaux et ses acteurs. Cette recherche étudie les conséquences de l'implémentation de la logique et des outils managériaux sur la profession d'infirmière en termes de contenu du travail et d'identité professionnelle. La reconfiguration des tâches au sein des structures hospitalières semble réduire l'autonomie de ces acteurs de terrain et affecter le sens que les infirmières donnent à leur travail. Par le prisme du pouvoir discrétionnaire, l'étude montre comment le personnel infirmier, principalement selon ses critères moraux, use de stratégies d'ajustement pour faire coïncider ses valeurs avec l'environnement professionnel. Toutefois, la disjonction entre les impératifs managériaux et les valeurs des infirmières engendre de la souffrance au travail. Dans une approche psychosociale, ce mémoire relie le mal-être des infirmières au concept de la « qualité empêchée » qui dévoile le mécanisme par lequel l'action des infirmières est privée en partie de son contenu.