Extract of the review of Lord Byron's Hours of idleness, from Edinburgh review, no. XXII., which occasioned "English bards and Scotch reviewers".

Mode of access: Internet.

Defence of Lieut. Col. Gardner Burbank : before the general court-martial, whereof Maj. Gen. Nathaniel Goodwin was president, held at Hathaway's Hall, in Worcester, on the 8th September, 1818, against charges preferred against him, by Col. Prentice Cushing and others : to which is prefixed an extract from the records of said court, containing all the evidence adduced upon his trials.

Mode of access: Internet.

Explanation of the views of the Society for Employing the Poor : with the constitution and by-laws; and an extract from the report of the managers, for the first three months, and a list of subscribers' names.

Shoemaker

An extract from the Report of the directors of Massachusetts State Prison, made to his excellency the governor and the honourable council. October 18, 1827. : Reviewing certain parts of the Second annual report of the Prison Discipline Society.

Mode of access: Internet.

Descendants of Jaquelin Ambler : with letters from his daughter, Mrs. Col. Ed. Carrington, and extract from his funeral sermon delivered by Rev. John Buchanan /

Mode of access: Internet.

Pabst Malt extract" giant bottle in window of Palmer's Pharmacy, 46 S. State St., Ann Arbor c. 1896-9

Glass negative is overexposed. hs13234: actual unchanged scan, hs13234alt: increased contrast in Photoshop to allow for image to be clearer

An historical account of Cumner; with some particulars of the traditions respecting the death of the Countess of Leicester; also an extract from Ashmole's Antiquities of Berkshire, relative to that transaction and illustrative of the romance of Kenilworth. To which is added an appendix, containing the original ballad of Cumner Hall, and other interesting matter.

Mode of access: Internet.

Report of the committee on the Wills Legacy; with an extract from the will of the late James Wills and the ordinances for the management of the Wills hospital.

Report addressed: To the Select and Common Councils of Philadelphia. - p. 3.

An aqueous extract of Fagonia cretica induces DNA damage, cell cycle arrest and apoptosis in breast cancer cells via FOXO3a and p53 expression

Background - Plants have proved to be an important source of anti-cancer drugs. Here we have investigated the cytotoxic action of an aqueous extract of Fagonia cretica, used widely as a herbal tea-based treatment for breast cancer. Methodology/Principal Findings - Using flow cytometric analysis of cells labeled with cyclin A, annexin V and propidium iodide, we describe a time and dose-dependent arrest of the cell cycle in G0/G1 phase of the cell cycle and apoptosis following extract treatment in MCF-7 (WT-p53) and MDA-MB-231 (mutant-p53) human breast cancer cell lines with a markedly reduced effect on primary human mammary epithelial cells. Analysis of p53 protein expression and of its downstream transcription targets, p21 and BAX, revealed a p53 associated growth arrest within 5 hours of extract treatment and apoptosis within 24 hours. DNA double strand breaks measured as ?-H2AX were detected early in both MCF-7 and MDA-MB-231 cells. However, loss of cell viability was only partly due to a p53-driven response; as MDA-MB-231 and p53-knockdown MCF-7 cells both underwent cell cycle arrest and death following extract treatment. p53-independent growth arrest and cytotoxicity following DNA damage has been previously ascribed to FOXO3a expression. Here, in MCF-7 and MDA-MB-231 cells, FOXO3a expression was increased significantly within 3 hours of extract treatment and FOXO3 siRNA reduced the extract-induced loss of cell viability in both cell lines. Conclusions/Significance - Our results demonstrate for the first time that an aqueous extract of Fagonia cretica can induce cell cycle arrest and apoptosis via p53-dependent and independent mechanisms, with activation of the DNA damage response. We also show that FOXO3a is required for activity in the absence of p53. Our findings indicate that Fagonia cretica aqueous extract contains potential anti-cancer agents acting either singly or in combination against breast cancer cell proliferation via DNA damage-induced FOXO3a and p53 expression.

First experimental demonstration of terabit interferometric drop, add and extract multiplexer

We present the first experimental implementation of an all-optical ROADM scheme for routing of individual channels within an all-optical OFDM superchannel. The interferometric technique demonstrated enables a fully flexible node, implementing the extraction, drop and addition of individual sub-channel.

Experimental implementation of an all-optical interferometric drop, add, and extract multiplexer for superchannels

We present the experimental implementation of an all-optical ROADM scheme for routing of an individual subchannel within an all-optical OFDM superchannel. The different functions required of optical node were demonstrated using interferometric technique with the extraction, drop, and addition of individual subchannel in a ten subchannels optically aggregated signal. The scheme we reported enables a fully flexible node compatible with future terabit per second superchannel transmission.