A herança genotípica proposta por Wilhelm Ludwig Johannsen

Conselho Nacional de Desenvolvimento Cientifico e Tecnológico (CNPq)

Investigação sobre a inclusão do episódio histórico da teoria genotípica de Wilhelm Ludwig Johannsen na formação inicial de professores e pesquisadores

This paper is part of a broader investigation on Epistemology of Biology carried out by a group of researchers from Cascavel/PR. It involves studies and research about biological thought on subjects such as the growing of the concepts of gene, genotype and phenotype. The aim of this research was to gather the undergraduate students of Biological Sciences’ views about the role played by the inclusion of a historical episode in the study group as a trigger for epistemological discussions and didactic reflections. Firstly, the students received Johannsen’s article “The genotype conception of heredity”, published in 1911 in the journal The American Naturalist, in which he proposed the concepts of genotype and phenotype, among other ones. After, there was a discussion held by group about the concepts proposed in the article taking into account the epistemological, historical and didactic aspects. Data collection occurred through the recording of the group discussions and individual interviews. The results suggest that the inclusion of this historical episode, enabled the participants to develop critical thinking through collective reflection on the meaning of biological knowledge in different contexts.

Destecendo uma carta pela estelística da expressão

We aim to analyse the text written by Eça de Queirós, “Carta ao Sr. Mollinet”, theorizing the stylistics of Marcel Cressot’s expression, called “the texture”. We discuss what is sought in the reading of a text nowadays: the form, the meaning or the form that produces meaning? Even though through stylistics there is identifi cation and description of the linguistic categories in the text, the morphological identifi cation in the enunciation level is emptied, if it is done separately. It is from the semantic-syntactic and melodic axes that Eça infl ates his characters with life. The characterization of Pacheco and Portuguese people is supported by the nexus, a producer of antagonistic meta-signifi cation in relation to the fi rst meaning. Eça’s irony results from the reverse meaning – from “ne pas dire”. The nexus is the great meaningful cohesion between logical and metalogic discourse – producing new signifi cations; multiplying verbal resources, which are created in order to metamorphose the linguistic sign into pictorial or iconic signs. The irony governs the whole constructive tessitura that stems from new referents, which result from demiurgical relations between themselves because of the metalogical process, as it allows to establish and change the direction when sign and referent, signifi er and signifi ed, utterance and context are related. The analysis of Eça’s selected text enriches the discoveries presented by the Stylistics of Expression.

Uma investigação com graduandos de licenciatura em Ciências Biológicas sobre a relação genotipo fenotipo na perspectiva da epistemologia de Gaston Bachelard

This work aims presenting and discussing the conceptual (re)construction of the Biological Sciences undergraduate students on the genotype-phenotype relationship. Data collection occurred through a group of researchers systematic monitoring, at weekly discussion meetings. The data were analyzed and discussed based on Bachelard epistemology foundations. The analysis of the results suggests that the inclusion of discussions of historical and epistemological issues, in that research group, favored reflections that contributed to the expansion of the thinking about the genotype-phenotype relationship.

Estudo genético de populações de soja com fonte de resistência à Heterodera glycines (raça 3) oriundas de topocruzamentos tipo alimento x tipo grão

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Seleção e associação genômica para precocidade sexual em bovinos da raça Nelore

Pós-graduação em Genética e Melhoramento Animal - FCAV

Remodelamento estrutural do tecido parabronquial de pintinhos em resposta à hipóxia durante o desenvolvimento fetal

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Estudo de genes de Candida albicans com função desconhecida quanto à formação de biofilme, características biológicas e interação patógeno- hospedeiro

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Leveduras patogênicas em fezes de aves de cativeiro: relação fenotípica e genotípica entre os isolados

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Hanseníase virchowiana: comprometimento medular

Paciente feminino 36 anos, com queixa de febre noturna, astenia, parestesia de membros inferiores, artralgia, hepatoesplenomegalia, lesões cutâneas, anemia hipocrômica, microcítica e linfopenia. Sorologia negativa para Hepatite B,C e HIV; FAN e anti-DNA também negativos. Histopatologia da medula óssea mostrou-se discretamente hipercelular, com presença de focos de histiócitos com citoplasma vacuolado (células pseudo-gaucher-like),aspecto megaloblástico, linfoplasmocitico e lipogranulomatoso. A coloração Ziehl- -Nielsen positivo; diagnóstico morfológico: micobacteriose de medula óssea. A cultura do sangue e do aspirado de medula óssea foi negativo para M.tuberculosis. Biópsia das lesões cutâneas máculas e pápulas hipercrômicas dos membros inferiores e superiores revelou hanseníase de padrão Vichowiana. A pesquisa BAAR pela Faraco demonstrou numerosos bacilos, sendo a maioria de padrão granuloso. Pacientes com hanseníase virchowiana tem acometimento cutâneo em 100% dos casos, o baço é o órgão mais frequentemente acometido com disseminação através do sangue periférico. O quadro anêmico e a linfopenia provavelmente se deve à cronicidade da infecção, levando a infiltração medular. A ocorrência do comprometimento medular em paciente com hanseníase Virchowiana é excepcional, mesmo em países endêmicos, e pode indicar necessidade de tratamento mais prolongado.

Resistência antimicrobiana em coliformes totais isolados de tanques de refrigeração de leite bovino

Milk that is adequate for consumption must be of hygienic quality, nutritional value, and should maintain its organoleptic properties. Isolation of fecal and/or total coliforms from bovine milk is considered an indicator of hygiene and good management practices, and can be used as a quality indicator. This study aimed to isolate, identify, and assess the resistance profile of coliforms isolated from collective bulk tanks and individual milk tanks. A total of 89 milk samples were collected from collective bulk tanks and, from these, 21 Klebsiella spp., one E. coli, and 29 Enterobacter spp. were isolated, whereas 102 milk samples from individual tanks showed isolation of one Klebsiella spp. and seven Enterobacter spp. In collective bulk tanks, at least 47% of Klebsiella spp. and Enterobacter spp. were resistant to cephalexin and 30% to ampicillin. From these, at least 24% showed multidrug resistance. Among the microorganisms isolated from the individual tanks, 85% or more were resistant to ampicillin. The ESBL phenotype and the blaTEM gene were detected in strains of Klebsiella spp. isolated from both tanks. It was concluded that contamination of milk with resistant total coliforms, and especially the storage of raw milk from several small producers in the collective bulk tank increase the risk of contamination.

O direito de pertencer a si mesmo: a despatologização do transexualismo e sua regulamentação jurídica como direito fundamental ao gênero

Pós-graduação em Direito - FCHS

Estudo do nível de infecção por Babesia bovis e Babesia bigemina em bovinos da raça Canchim naturalmente infestados com o carrapato Rhipicephalus (Boophilus) microplus

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Seleção genômica para características longitudinais de bovinos da raça Holandesa

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Inibição da metástase via transição epitélio-mesenquimal por shRNA, metformina e Y27632 em neoplasia mamária

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)