Cost-Effectiveness of Rotavirus Vaccination for Under-Five Children in Iran

Background: Rotavirus diarrhea is one of the most important causes of death among under-five children. Anti-rotavirus vaccination of these children may have a reducing effect on the disease. Objectives: this study is intended to contribute to health policy-makers of the country about the optimal decision and policy development in this area, by performing cost-effectiveness and cost-utility analysis on anti-rotavirus vaccination for under-5 children. Patients and Methods: A cost-effectiveness analysis was performed using a decision tree model to analyze rotavirus vaccination, which was compared with no vaccination with Iran’s ministry of health perspective in a 5-year time horizon. Epidemiological data were collected from published and unpublished sources. Four different assumptions were considered to the extent of the disease episode. To analyze costs, the costs of implementing the vaccination program were calculated with 98% coverage and the cost of USD 7 per dose. Medical and social costs of the disease were evaluated by sampling patients with rotavirus diarrhea, and sensitivity analysis was also performed for different episode rates and vaccine price per dose. Results: For the most optimistic assumption for the episode of illness (10.2 per year), the cost per DALY averted is 12,760 and 7,404 for RotaTeq and Rotarix vaccines, respectively, while assuming the episode of illness is 300%, they will be equal to 2,395 and 354, respectively, which will be highly cost-effective. Number of life-years gained is equal to 3,533 years. Conclusions: Assuming that the illness episodes are 100% and 300% for Rotarix and 300% for Rota Teq, the ratio of cost per DALY averted is highly cost-effective, based on the threshold of the world health organization (< 1 GDP per capita = 4526 USD). The implementation of a national rotavirus vaccination program is suggested.

The Amplifier - v. 11, no. 5

In this issue...Mary McGrath, Geophysics Club, Marcus Daly, Intramurals, Constitution, Circle K Club, Homecoming, Kiwanis Club, Rose Parade

The Amplifier - v. 12, no. 3

In this issue...Business Management, US Geological Survey, Finlen Hotel, Magma Yearbook, Copper Guard, Somewhere Else Coffee House, Marcus Daly Statue

The Amplifier - v. 12, no. 7

In this issue...International Club, Easter Dance, Tiddledywinks, Mine Rescue, First Aid, Mineral Dressing, College Days, Circle K Club, Sigma Xi

The Amplifier - v. 12, no. 9

In this issue...College Days, Peace Corps, Baseball, Coast Guard, Drama Club, First Aid, Montana Institute of Art, The Anaconda Company, Butte Symphony, Student Opinion

The Amplifier - v. 13, no. 4

In this issue...NASA, College Business Symposium, Marcus Daly, Charlie Brown, Caterpillar Company, Copper Lounge, Student Union Building

The Amplifier - v. 13, no. 11

In this issue...75th Anniversary, Montana State Highway Department, Geology Field Camp, Gallatin Valley, Uuno M Sahinen, Marcus Daly, Copper Kings, Montana Tech Presidents

The Amplifier - v. 15, no. 4

In this issue...Pintlar Peaks, SUB, Bridge Building Contest, Senator Mike Mansfield, Montana Mining Law, Mathematics, Theta Tau, Marcus Daly, Coeds

The Amplifier - v. 15, no. 5

In this issue...Coach Charlie Armey, Veterans, Marcus Daly, Campus Pollution, Satellites, Campus Parking, Elks National Foundation, Kieth Strom, International Club

The Amplifier - v. 15, no. 7

In this issue...Liberal Art Degree, Climbing Club, Caterpillar Tractor Company, Gary Lee Knudson, Wilhelm's Flower Shop, Marcus Daly, Baseball, Du Pont Research

The Amplifier v. 16, no. 7

In this issue...Spurettes, Art Club, Petroleum Department, Xerox Effective Listening Course, Miners Bank, Comics, KXLF Radio, Marcus Daly, Baseball, Repertory Theater

The Amplifier - v. 17, no. 3

In this issue...ASARCO, East Helena, Spurettes, Main Hall, G I Bill, FM Radio, Marcus Daly, Library, Computer Center, Free Films, Copper Bowl Poll, Volleyball

The Amplifier - v. 17, no. 7

In this issue...Marcus Daly, Life Insurance, Butte Walk for Mankind, library Building, peace Corps, VISTA, Egg Drop, College Days, Student Council, Mountaineer Club

Patient experiences of a bariatric group programme for managing obesity:a qualitative interview study

Objectives: People with obesity experience a range of physical and psychological ill-health outcomes. This study examined patients’ experiences of a group-based programme for the management of morbid obesity delivered within the UK National Health Service. The focus of the study was on the emerging dynamic of the group and patients’ perceptions of its impact on health outcomes. Design: A qualitative interview study was conducted and involved patients recruited from a Tier 3 bariatric service in South West England. Verbatim transcripts were analysed using thematic analysis. Methods: Twenty patients (12 females) with a BMI ≥ 35 kg/m2 participated in a semi-structured one-to-one interview. Participants had been registered with the bariatric service for at least 6 months. None of the participants had had bariatric surgery. Results: Most participants felt that they had benefited from participating in the group programme and talked about the group as a resource for lifestyle change. Participants’ narratives centred on the emergence of a sense of self based upon their participation in the group: establishing psychological connections to other patients, or shared social identity, was regarded as a key mechanism through which the programme's educational material was accessed, and underpinned the experience of social support within the group. Through interaction with other patients, involving the sharing of personal experiences and challenges, participants came to experience their weight ‘problem’ through a collective lens that they felt empowered them to initiate and sustain individual lifestyle change. Discussion: Bariatric care groups have the potential to support lifestyle change and weight loss and may help address the psychological needs of patients. Nurturing a sense of shared social identity amongst patients with morbid obesity should be a core aim of the care pathway and may provide the foundation for successful translation of dietetic content in group programmes.

Challenges in imaging and predictive modeling of rhizosphere processes

Background Plant-soil interaction is central to human food production and ecosystem function. Thus, it is essential to not only understand, but also to develop predictive mathematical models which can be used to assess how climate and soil management practices will affect these interactions. Scope In this paper we review the current developments in structural and chemical imaging of rhizosphere processes within the context of multiscale mathematical image based modeling. We outline areas that need more research and areas which would benefit from more detailed understanding. Conclusions We conclude that the combination of structural and chemical imaging with modeling is an incredibly powerful tool which is fundamental for understanding how plant roots interact with soil. We emphasize the need for more researchers to be attracted to this area that is so fertile for future discoveries. Finally, model building must go hand in hand with experiments. In particular, there is a real need to integrate rhizosphere structural and chemical imaging with modeling for better understanding of the rhizosphere processes leading to models which explicitly account for pore scale processes.