Herpetofauna of Paranapiacaba: expanding our knowledge on a historical region in the Atlantic forest of southeastern Brazil

The largest area of preserved Atlantic forest is located in the southern portion of Brazil. The region of Paranapiacaba is depicted in Brazilian zoological studies as one of the first and most intensely sampled areas of the state of São Paulo.We provide a concise list of reptiles and amphibians from the Paranapiacaba Municipal Park. It represents the first comprehensive survey of the group in the area. We recorded 136 species of reptiles and amphibians from field surveys, museum collections and the literature. The anuran diversity of Paranapiacaba is greater than that of Estação Ecológica de Boracéia, which has been considered the most distinctive areas in São Paulo in terms of amphibian diversity. The rich history of herpetological research in the region, including the occurrence of the two most threatened species in Brazil, converts the area to an important conservation landmark for the Brazilian herpetofauna.

Biotechnology of polyketides: new breath of life for the novel antibiotic genetic pathways discovery through metagenomics

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A representação da informação Arquivística: Uma Análise do discurso teórico e institucional a partir dos contextos Espanhol, Canadense e Brasileiro

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

NOVEL PREDICTORS OF PERITONITIS-RELATED OUTCOMES IN THE BRAZPD COHORT

Introduction: Peritonitis remains the main cause of peritoneal dialysis (PD) technique failure worldwide, despite significant reductions in infection rates observed over the past decades. Several studies have described risk factors for peritonitis, technique failure and mortality. However, there are scarce data regarding predictors of complications during and after a peritonitis episode. The aim of our study was to analyze predictors of peritonitis-related outcome in the Brazilian Peritoneal Dialysis study (BRAZPD) cohort.Methods: All adult incident patients recruited in the BRAZPD Study between December 2004 and October 2007, who remained at least 90 days on PD and presented their first peritonitis episode (n = 474 patients) were included in the study. The endpoints analyzed were non-resolution, death due to a peritonitis episode and long-term technique survival after a peritonitis episode.Results: In the multivariable regression, non-resolution was independently associated with older age (odds ratio (OR) 1.02; p < 0.01), collagenosis as the primary renal disease (OR 4.6; p < 0.05) and Pseudomonas spp as etiological agent (OR 2.9; p < 0.05). Patients who were transferred from APD to CAPD during peritonitis therapy presented a higher risk of non-response (OR 2.5; p < 0.05). The only factor associated with death during a peritonitis episode was older age (OR 1.04; p < 0.05). Exposure to vancomycin and male gender were the independent predictors of long-term technique failure (OR 2.2; p < 0.01).Conclusion: Apart from confirming previous observations of the negative impact of older age and Pseudomonas spp peritonitis on outcomes, we observed that collagenosis may negatively impact response to treatment and exposure to vancomycin may possibly reduce long-term technique survival. It is important to emphasize that the association of vancomycin with technique failure does not prove causality. These findings shed light on new factors predicting outcome when peritonitis is diagnosed.

Polymorphic Sites at the 3 ' Untranslated Region of the HLA-G Gene Are Associated with Differential hla-g Soluble Levels in the Brazilian and French Population

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A nonsynonymous mutation at HLA-E defines the new E*01:06 allele in Brazilian individuals

We report a novel nonclassical class I HLA-E*01:06 allele observed in Brazilian individuals.

Structure of the polypeptide crotamine from the Brazilian rattlesnake Crotalus durissus terrificus

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Estimates of genetic parameters for total milk yield over multiple ages in Brazilian Murrah buffaloes using different models

The objective of this study was to estimate variance components and genetic parameters for accumulated 305-day milk yield (MY305) over multiple ages, from 24 to 120 months of age, applying random regression (RRM), repeatability (REP) and multi-trait (MT) models. A total of 4472 lactation records from 1882 buffaloes of the Murrah breed were utilized. The contemporary group (herd-year-calving season) and number of milkings (two levels) were considered as fixed effects in all models. For REP and RRM, additive genetic, permanent environmental and residual effects were included as random effects. MT considered the same random effects as did REP and RRM with the exception of permanent environmental effect. Residual variances were modeled by a step function with 1, 4, and 6 classes. The heritabilities estimated with RRM increased with age, ranging from 0.19 to 0.34, and were slightly higher than that obtained with the REP model. For the MT model, heritability estimates ranged from 0.20 (37 months of age) to 0.32 (94 months of age). The genetic correlation estimates for MY305 obtained by RRM (L23.res4) and MT models were very similar, and varied from 0.77 to 0.99 and from 0.77 to 0.99, respectively. The rank correlation between breeding values for MY305 at different ages predicted by REP, MT, and RRM were high. It seems that a linear and quadratic Legendre polynomial to model the additive genetic and animal permanent environmental effects, respectively, may be sufficient to explain more parsimoniously the changes in MY305 genetic variation with age.

Metamorfoses da medicalização e seus impactos na família brasileira

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

As marcas da memória na escrita de As meninas de Lygia Fagundes Telles

Pós-graduação em Estudos Literários - FCLAR

O retorno: identidades à deriva no romance português contemporâneo

This paper concentrates on the analysis of how the typical voices of History are manifested, which is achieved by the aesthetics of the contemporary Portuguese narrative, as it aims at the same time the reflexion and the reformulation of the Lusitanian cultural imaginary in the course of O retorno, a novel by Dulce Maria Cardoso. The hypothesis that arises is that the trajectory of Rui’s individual experience, as wells as the other’s characters “retornados” looking for identity, is parallel to the proposed revision of the Portuguese nation collective cultural imaginary in the decolonization context, after the 25th April Revolution. It is its objective to investigate how the historical processes concerned to the concepts of exile and uprooting, displacement and belonging (BAUMAN, 2005) are fictionalized in the novel, seen as motes for Rui’s pursuit for identity and for the revision of the Portuguese Destiny theme

Sistema jagunço: localismo e universalismo em Grande sertão : veredas

Under different perspectives of interpretation and analysis, the notions of localism and universalism in the fictional production of Guimarães Rosa have been strongly explored by the criticism, especially in Grande sertão: veredas [The devil to pay in the backlands], in which these two dimensions – overlapped and complementary – become more intricate and profuse. Taking the analytical line of historical, social and political dimensions of the novel for granted – not regarding it as an essay or strict allegory of the country – the present study proposes a new reading of the composition with the interpretation of the articulation of these two dimensions in the forming of the “jagunço system” (ROSA, 1970, p.391), that is a concept created by Guimarães Rosa and which transcends the historical and sociological reality. The articulation of the social, political and cultural elements figure in Guimarães Rosa’s fiction and becomes an issue for wider debates and reflections, so that the particular element of the novel enables a universal survey. Based on diverse critical apprehensions of the novel, this paper aims to investigate the levels of the literary composition in which the local-universal articulation associated with the representation of the jagunço is constructed. In order to do that, the theoretical study is based on three dimensions of studies: a) critical essays about Guimarães Rosa, the totality of his work and specific critical essays about Grande sertão: veredas [The devil to pay in the backlands] and the “jagunço system”, b) theoretical apparatus concerning the history, the politics and the Brazilian culture related to the cangaço; and c) theoretical subsidies for the study of the narrative

Personagens e espaço em romances de Aluísio Azevedo

The characters of O mulato, Casa de pensão and O cortiço, well written books by the writer Aluísio Azevedo, may be considered predominantly flat, for they were built with a single or few features. This kind of character can be even defined by the type, which represents certain dominant features (professional, psychological, cultural, economic, religious, etc.) from the diegetic universe in which the action takes place. This character subcategory is present in certain artistic periods such as Realism and Naturalism, and can be understood as the main character between the individual and the collective, between the concrete and the abstract. Yet, the social space, in the novels of the above mentioned literary movements configures itself, especially in terms of the presence and types of extras: it is about describing environments that illustrate, almost always, in a historical period context of critical intent, vices and deformations of the society, as we can see depicted in the three novels of the author. In turn, the narrative categories that most decisively influence the space representation are the instance (the narrator) and the narrative perspective (focusing). In the case of O mulato, Casa de pensão and O cortiço, the dominance is in choosing the omniscient narrator, who prefers a panoramic view, limited to an exterior and strictly objective description. The survey was developed through readings, literary cataloging and corpus discussions, with a theoretical basis determined by three dimensions: a) critical essays about the author and his works, such as those by Jean-Yves Mérian, Aluísio Azevedo, vida e obra: (1857-1913) and parts of the literature histories which deal with Naturalism, such as those by Alfredo Bosi, História concisa da literatura brasileira, b) theoretical studies about the novel character, such as those by Antonio Candido, A personagem do romance, and the romantic space ...

O gênero em questão: crítica e formação nos Bildungsromane The Secret Life of Bees, de Sue Monk Kidd, e Sapato de salto, de Lygia Bojunga

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O romance como veículo de preenchimento da falta humana: Reparação de Ian McEwan

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)