Another angle on contact lens surface analysis

Purpose: Dynamic contact angle (DCA) methods have advantages over other contact angle methodologies, not least that they can provide more than single contact angle values. Here we illustrate the use of DCA analysis to provide “fingerprint” characterisation of contact lens surfaces, and the way that different materials change in the early stages of wear. Method: The DCA method involves attaching to a microbalance weighted strips cut from a lens. The strips are then cyclically inserted into and removed from an aqueous solution. Conventionally, readings of force taken from linear portions of the resultant dipping curves are translated into advancing (CAa) and receding contact (CAr) angles. Additionally, analysis of the force versus immersion profile provides a “fingerprint” characterisation of the state of the lens surface. Results: CAa and CAr values from DCA traces provide a useful means of differentiating gross differences in hydrophilicity and molecular mobility of surfaces under particular immersion and emersion conditions, such as dipping rate and dwell times. Typical values for etafilcon A (CAa:63.1; CAr:37) and balafilcon B (CAa:118.4; CAr:36.4) illustrate this. Surface modifications induced in lens manufacture are observed to produce not only changes in these value, which may be small, but also changes in the DCA “fingerprint” (slope, undulations, length of plateau). Interestingly, similar changes are induced in the first few hours of lens wear with some lens-patient combinations. Conclusions: Although single parameter contact angles are useful for material characterisation, information of potential clinical interest can be obtained from more detailed analysis of DCA traces.

Contribution of the vasculature to the Alzheimer's disease process

One of the pathological hallmarks of Alzheimer's disease (AD) brain is extracellular β-amyloid (Aβ) plaques containing 39-42 amino acid Aβ peptides. The deposition of Aβ around blood vessels, known as Cerebral amyloid angiopathy (CAA), is also a common feature in AD brain. Vascular density and cerebral blood flow are reduced in AD brains, and vascular risk factors such as hypertension and diabetes are also risk factors for AD. We have shown previously that Aβ peptides can potently inhibit angiogenesis both in-vitro and in-vivo, but the mechanism of action for this effect is not known. Therefore, my first hypothesis was that particular amino acid sequence(s) within the Aβ peptide are required for inhibition of angiogenesis. From this aim, I found a peptide sequence which was critical for anti-angiogenic activity (HHQKLVFF). This sequence contains a heparan sulfate proteoglycan growth factor binding domain implying that Aβ can interfere with growth factor signaling. Leading on from this, my second hypothesis was that Aβ can inhibit angiogenesis by binding to growth factor receptors. I found that Aβ can bind to Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2), and showed that this is one mechanism by which Aβ can inhibit angiogenesis. Since the vasculature is disrupted in AD brains, I investigated whether a strategy to increase brain vascularization would be beneficial against AD pathology. Therefore, my third hypothesis was that voluntary exercise (which is known to increase brain vascularization in rodents) can ameliorate Aβ pathology, increase brain vascularization, and improve behavioral deficits in a transgenic mouse model of AD. I found that exercise has no effect on Aβ pathology, brain vascularization or behavioral deficits. Therefore, in the transgenic mouse model that I used, exercise is an ineffective therapeutic strategy against AD pathology and symptoms.

Commuter Airlines:Their Changing Role

In - Commuter Airlines: Their Changing Role – an essay by J. A. F. Nicholls, Transportation Coordinator, Department of Marketing and Environment, College of Business Administration, Florida International University, Nicholls initially observes: “The great majority of airline passenger miles flown in the United States are between large conurbations. People living in metropolitan areas may be quite unaware of commuter airlines and their role in our transportation system. These airlines are, however, communications lifelines for dwellers in small - and not so small - towns and rural areas. More germanely, commuter airlines have also developed a pivotal role vis-a-vis the major carriers in this country. The author discusses the antecedents of the commuter Airlines, their current role, and future prospects.” Huh; conurbations? Definition: [n.] a large urban area created when neighboring towns spread into and merge with each other In providing a brief history on the subject of commuter airlines, Nicholls states: “…there had been a sort of commuter airline as far back as 1926 when, for example, the Florida Airways Corporation provided flights between Jacksonville and Atlanta, Colonial Air Lines between New York and Boston, and Ford Air Transport from Detroit to Cleveland.” “The passage of the Civil Aeronautics Act in 1938 was pivotal in encouraging and developing a passenger orientation by the airlines…” Nicholls informs you. Nicholls provides for the importance of this act by saying: “The CAA was empowered to act “in the public interest and in accordance with the public convenience and necessity.” Only the CAA itself could determine what constituted the “public convenience and necessity.” Nobody, however, could provide air transportation for public purposes without a Certificate of Public Convenience and Necessity, dispensed by the CAA.” The author wants you to know that this all happens in the age of airline regulation; that is to say, pre de-regulation i.e. 1978. Airlines could not and did not act on their own behalf; their actions were governed by the regulating agency, that being the Civil Aeronautics Board [CAB], who administered the conditions set forth by the CAA. “In 1944 the CAB introduced a new category of service called feeder airlines to provide local service-short-haul, low density-for smaller communities. These carriers soon became known as air taxis since they operated as common carriers, without a regular schedule,” says Nicholls in describing the evolution of the service. In 1969 the CAB officially designated these small air carriers as commuter airlines. They were, and are subject to passenger limits and freight/weight restrictions. Nicholls continues by defining how air carriers are labeled and categorized post 1978; in the age of de-regulation.

Diabetes Self Management: Are Cuban Americans Receiving Quality Health Care?

Objectives: We investigated the relationship among factors predicting inadequate glucose control among 182 Cuban-American adults (Females=110, Males=72) with type 2 diabetes mellitus (CAA). Study Design: Cross-sectional study of CAA from a randomized mailing list in two counties of South Florida Methods: Fasted blood parameters and anthropometric measures were collected during the study. BMI was calculated (kg/ m2). Characteristics and diabetes care of CAA were self-reported Participants were screened by trained interviewers for heritage and diabetes status (inclusion criteria: self-reported having type 2 diabetes; age  35 years, male and female; not pregnant or lactating; no thyroid disorders; no major psychiatric disorders). Participants signed informed consent form. Statistical analyses used SPSS and included descriptive statistic, multiple logistic and ordinal logistic regression models, where all CI 95%. Results: Eighty-eight percent of CAA had BMI of ≥ 25 kg/ m2. Only 54% reported having a diet prescribed/told to schedule meals. We found CAA told to schedule meals were 3.62 more likely to plan meals (1.81, 7.26), p<0.001) and given a prescribed diet, controlling for age, corresponded with following a meal plan OR 4.43 (2.52, 7.79, p<0.001). The overall relationship for HbA1c < 8.5 to following a meal plan was OR 9.34 (2.84, 30.7. p<0.001). Conclusions: The advantage of having a medical professional prescribe a diet seems to be an important environmental support factor in this sample’s diabetes care, since obesity rates are well above the national average. Nearly half CAA are not given dietary guidance, yet our results indicate CAA may improve glycemic control by receiving dietary instructions.

The song of humpback whale and the potential effects of whale-watching in the abrolhos bank, BA, Brazil

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

The song of humpback whale and the potential effects of whale-watching in the abrolhos bank, BA, Brazil

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Áreas importantes para a conservação do último grande herbívoro da caatinga potiguar: o veado-catingueiro (Mazama gouazoubira)

Cervídeo Mazama gouazoubira é a espécie de veado que possui maior distribuição dentre as espécies sul americanas. Aspectos da vegetação, predação, competição, caça e perda de habitat são fatores importantes para compreender a distribuição espacial de herbívoros na paisagem. Dessa forma, considerando a falta de estudos de mamíferos de médio e grande porte na Caatinga, objetivamos compreender quais os fatores ambientais e antrópicos que influenciam a ocupação do veado-catingueiro (M. gouazoubira) na região semiárida do estado do Rio Grande do Norte, Brasil. O estudo foi realizado em 10 áreas amostrais e utilizamos armadilhas fotográficas para amostragem e modelos de ocupação foram construídos representando nossas hipóteses biológicas. Os modelos foram ranqueados através dos valores obtidos do AIC. As variáveis cobertura vegetal de caatinga e densidade da vegetação mostraram maior efeito, já a caatinga arbórea mostrou um efeito menor, sugerindo que a espécie é altamente dependente da vegetação para ocorrer, possuindo menor dependência de caatinga arbórea. Esperamos que nossos resultados possam ser utilizados como suporte para planos de manejo e criação de novas unidades de conservação no estado.

Promoção da saúde e trabalho: um ensaio analítico

CAVALCANTE,Cleonice Andréa Alves, NÓBREGA, Jussara Azevedo Bezerra da, ENDERS,Bertha Cruz, MEDERIROS, Soraya Maria de. Promoção da saúde e trabalho: um ensaio analítico. Revista Eletrônica de Enfermagem. v.10,n.1 p.241-248.2008. Disponível em :.

International capital and new frontiers of biofuel production in brazilian midwest

v. 18, n.1, jan./mar. 2016.

Negligent Eye

This presentation was both an illustrated lecture and a published paper presented at the IMPACT 9 Conference Printmaking in the Post-Print Age, Hangzhou China 2015. It was an extension of the exhibition catalogue essay for the Bluecoat Gallery Exhibition of the same name. In 2014 I curated an exhibition The Negligent Eye at the Bluecoat Gallery in Liverpool as the result of longstanding interest in scanning and 3D printing and the role of these in changing the field of Print within Fine Art Practice. In the aftermath of curatingshow I have continued to reflect on this material with reference to the writings of Vilém Flusser and Hito Steyerl. The work in the exhibition came from a wide range of artists of all generations most of whom are not explicitly located within Printmaking. Whilst some work did not use any scanning technology at all, a shared fascination with the particular translating device of the systematizing ‘eye’ of a scanning digital video camera, flatbed or medical scanner was expressed by all the work in the show. Through writing this paper I aim to extend my own understanding of questions, which arose from the juxtapositions of work and the production of the accompanying catalogue. The show developed in dialogue with curators Bryan Biggs and Sarah-Jane Parsons of the Bluecoat Gallery who sent a series of questions about scanning to participating artists. In reflecting upon their answers I will extend the discussions begun in the process of this research. A kind of created attention deficit disorder seems to operate on us all today to make and distribute images and information at speed. What value do ways of making which require slow looking or intensive material explorations have in this accelerated system? What model of the world is being constructed by the drive to simulated realities toward ever-greater resolution, so called high definition? How are our perceptions of reality being altered by the world-view presented in the smooth colourful ever morphing simulations that surround us? The limitations of digital technology are often a starting point for artists to reflect on our relationship to real-world fragility. I will be looking at practices where tactility or dimensionality in a form of hard copy engages with these questions using examples from the exhibition. Artists included in the show were: Cory Arcangel, Christiane Baumgartner, Thomas Bewick, Jyll Bradley, Maurice Carlin, Helen Chadwick, Susan Collins, Conroy/Sanderson, Nicky Coutts, Elizabeth Gossling, Beatrice Haines, Juneau Projects, Laura Maloney, Bob Matthews, London Fieldworks (with the participation of Gustav Metzger), Marilène Oliver, Flora Parrott, South Atlantic Souvenirs, Imogen Stidworthy, Jo Stockham, Wolfgang Tillmans, Alessa Tinne, Michael Wegerer, Rachel Whiteread, Jane and Louise Wilson. Scanning, Art, Technology, Copy, Materiality.

Testing a linear propagation module on some acoustic scattering problems

Abstract not available

Sensibilité des simulations de neige du modèle SNOWPACK à la paramétrisation de la végétation dans la Réserve Faunique Chic-Chocs

Au Canada, les avalanches constituent le géorisque le plus dangereux en période hivernale. On enregistre annuellement d’importants coûts économiques et sociaux associés aux impacts de ce phénomène naturel. Par exemple, la fermeture de routes en cas de risque d’avalanche est estimée à 5 millions de dollars (Jamieson et Stethem, 2002). La prévision des avalanches est, de nos jours, la meilleure méthode afin d’éviter ces coûts. Au Canada, cela s’effectue de façon ponctuelle à l’aide de méthodes manuelles tel que le test de compression (CAA, 2014). Les modèles de simulation du couvert neigeux permettent d’étendre les prévisions à l’ensemble d’une région et ainsi, atteindre certains lieux difficilement accessibles pour l’homme. On tente actuellement d’adapter le modèle SNOWPACK aux conditions canadiennes et plusieurs études ont eu pour but d’améliorer les simulations produites par celui-ci. Cette étude vise donc également l’amélioration des simulations par l’intégration des paramètres de végétation. L’objectif de l’étude est de paramétrer, pour la première fois, le module de végétation de SNOWPACK avec les données récoltées dans la réserve faunique des Chic-Chocs. Nous pourrons ainsi évaluer l’impact de la végétation sur la modélisation du couvert nival. Nous avons donc, lors de sorties de terrain, recueillis les données de neige et de végétation au niveau de quatre sites d’étude. Nous avons par la suite réalisé les simulations avec SNOWPACK et comparer les résultats des simulations avec et sans végétation aux données de terrain. L’étude nous révèle que le modèle diminue la quantité de neige au sol ainsi que la densité du manteau neigeux en présence de végétation. De plus nous avons pu constater que l’inclusion du module de végétation permet d’obtenir des données qui se rapprochent davantage de ce qui a été observé sur le terrain.

Escherichia coli productor de toxina Shiga en alimentos : antecedentes y situación actual de la legislación alimentaria en Argentina

Escherichia coli productor de toxina Shiga (STEC) es un grupo bacteriano asociado a enfermedades transmitidas por alimentos. Algunos serotipos de STEC representan un grave problema para la Salud Pública, causando diarrea, colitis hemorrágica y síndrome urémico hemolítico (SUH). En Argentina el SUH es endémico y constituye la primera causa de insuficiencia renal aguda en niños menores de 5 años. Los recientes brotes en el mundo de enfermedades causadas por E. coli no-O157, han resultado fuertemente impactantes no solo a nivel de la salud pública sino también a nivel comercial. Estos eventos han puesto en evidencia la necesidad de contar con un nuevo marco legislativo en materia alimentaria. En Argentina la reciente aprobación por parte dela Comisión Nacional de Alimentos (CONAL) respecto de la incorporación al Código Alimentario Argentino (CAA) de criterios microbiológicos que incluyen la ausencia de STEC no-O157 favorece la prevención de aquellos serogrupos prevalentes en el país. Estos criterios microbiológicos fueron establecidos para carne picada fresca, alimentos listos para consumir, chacinados, frutas, verduras y hortalizas mínimamente procesadas. Es fundamental destacar que los serogrupos (O145, O121, O26, O111 y O103) propuestos para la modificación del CAA son aquellos que exige la normativa actual de Estados Unidos, y los que indica la Norma ISO 13136, hoy por hoy, la utilizada en la Unión Europea (UE) como referencia en el tema. Esto conlleva beneficios futuros, ya que, al homologar las mismas exigencias técnicas microbiológicas se facilitara el intercambio de alimentos entre países. Teniendo en cuenta que la falta de criterios uniformes regulatorios a nivel internacional, generan discrepancias que traen aparejados, obstáculos técnicos al comercio (OTC), pudiendo llegar a ser barreras paraarancelarias encubiertas, con consiguientes perjuicios económicos que pueden ser transferidos a las naciones exportadoras de alimento.

Ecology and physical condition of red deer in the Iberian Peninsula: implications for management

The red deer (Cervus elaphus) is currently one of the most widespread and abundant wild ungulates in the Iberian Peninsula and is extremely important both ecologically, as a key species for the functioning of the ecosystems, and economically, as a major game species. In Iberia, red deer populations are subjected to different management systems that may affect the physical condition of the individuals, with further consequences for population dynamics. Studies investigating the effects of management practices and environmental conditions on the performance of red deer are still rare regarding Mediterranean ecosystems. Much of the knowledge concerning the ecology of red deer and the impact of management on its physical condition is based on studies conducted in northern and central regions of Europe, where climatological features and management practices differ from those observed in the Mediterranean areas of Iberia. Studies on a biogeographical scale can provide important insights into the relationships between species and a particular environment and contribute to the development of more targeted and appropriate management practices. The optimisation of sampling procedures and the fine-tuning of pre-existing analytical techniques are also fundamental to a more cost-effective monitoring and, therefore, are of enormous value to wildlife managers. In this context, the main aims of this thesis were: 1) to optimise the procedures used to assess the physical condition of red deer; and 2) to identify relevant management and environmental factors affecting the nutritional condition and stress physiology of red deer in the Mediterranean ecosystems of Iberia, as well as any potential interactions between those factors. Two studies with a methodological focus, presented in the first part of the thesis, demonstrated that the physical condition of red deer can be evaluated more simply, using more cost- and time-effective procedures than those traditionally used: i) it was shown that only one kidney and its associated fat is enough to assess nutritional condition in red deer; and ii) the feasibility of using near infrared spectroscopy to predict the concentrations of stress hormone metabolites was demonstrated using faeces of red deer for the first time. Subsequently, two large-scale observational studies, conducted in representative red deer populations found in Mediterranean Iberia, highlighted the importance of considering seasonal environmental variations and variables related to hunting management practices to better understand the nutritional and physiological ecology of red deer. High population densities had adverse effects on the nutritional condition of the deer and were associated with increased stress levels in natural populations without supplementary feeding. Massive hunting events involving the use of hounds were also identified as a potential source of chronic stress in red deer. The research presented in this thesis has clear implications regarding the management and monitoring of red deer populations in Mediterranean environments and is intended to help wildlife managers to implement more effective monitoring programmes and sustainable management practices.

Reseñas

Esta revista contiene extractos de artículos publicados en todo el mundo sobre productos tropicales, problemas de los trópicos y la investigación tropical, a excepción de la medicina humana y de la higiene tropical. Esta apropiada de manera excelente para poner al corriente a los interesados. El contenido de cada revista, ordenado según la clasificación decimal, se divide en los párrafos siguientes: economía, ciencias sociales, programas de bienestar, organizaciones internacionales, investigación, reseñas, adquisición de libros. Los informes sobre los productos agrícolas, tratan por ejemplo del henequén, algodón, caña de azúcar, tabaco, café, té, etc. La publicación de Octubre de 23 de 1954 contiene, fuera de otros: las aves en nueva Guinea central; conservación del suelo en África del Sur; cultivo de arroz en Japón; cultivo de café en Brasil; arboles de sombra para el cacao en el Congo Belga, perdidas en la preparación del aceite de palmeras; la enfermedad rosada del caucho; lucha contra los insectos perjudiciales; estudios forestales en la Costa de Marfil, etc. Es porque la revista trata de todos los bienes agrícolas producidos en El Salvador.