Intraoperative image-guided navigation system: development and applicability in 65 patients undergoing liver surgery

Background Image-guided systems have recently been introduced for their application in liver surgery.We aimed to identify and propose suitable indications for image-guided navigation systems in the domain of open oncologic liver surgery and,more specifically, in the setting of liver resection with and without microwave ablation. Method Retrospective analysis was conducted in patients undergoing liver resection with and without microwave ablation using an intraoperative image-guided stereotactic system during three stages of technological development (accuracy: 8.4 ± 4.4 mm in phase I and 8.4 ± 6.5 mm in phase II versus 4.5 ± 3.6 mm in phase III). It was evaluated, in which indications image-guided surgery was used according to the different stages of technical development. Results Between 2009 and 2013, 65 patients underwent image-guided surgical treatment, resection alone (n=38), ablation alone (n =11), or a combination thereof (n =16). With increasing accuracy of the system, image guidance was progressively used for atypical resections and combined microwave ablation and resection instead of formal liver resection (p<0.0001). Conclusion Clinical application of image guidance is feasible, while its efficacy is subject to accuracy. The concept of image guidance has been shown to be increasingly efficient for selected indications in liver surgery. While accuracy of available technology is increasing pertaining to technological advancements, more and more previously untreatable scenarios such as multiple small, bilobar lesions and so-called vanishing lesions come within reach.

Challenges to the Patent System in face of Open Hardware

Dannie Jost gave a presentation outlining some of the challenges to the patent system presented by open source hardware at the "Open Knowledge Festival", under the topic stream treating open design, hardware, manufacturing and making; September 19, 2012; Helsinki, Finland. This topic stream generated considerable discussion, and it serves to educate an audience that is usually very adverse to patents and copyright, and helps the researcher understand the issuing conflicts surrounding emerging technologies, in particular digital technologies, and the maker movement (digitally enabled).

Student move-in: Luggage and furniture in open back of station wagon, ca. 1981

frame 27

Electrical control system for automatic feed grinding /

Cover title.

Long life hydraulic brake system. Final technical report.

National Highway Traffic Safety Administration, Washington, D.C.

Long life hydraulic brake system. Summary report. Final report.

National Highway Traffic Safety Administration, Washington, D.C.

The life and times of Fray Junípero Serra, O.F.M.; or, The man who never turned back, (1713-1784), a biography.

Includes index.

Origin of the the [!] new system of manufacture, commonly called "power-loom weaving," and the purposes for which this system was invented and brought into use fully explained in a narrative, containing William Radcliffe's struggles through life to remove the cause which has brought this country to its present crisis /

Mode of access: Internet.

Triptych, open, Virgin and Child Enthroned, Scenes from the Life of the Virgin

Painting, Crusader, 13th century; 22-23/64 x 18-25/32 in. (center); 21-9/64 x 8-35/64 in. (each wing); tempera, gold and silver on wood

New guide to health; or, Botanic family physician, containing a complete system of practice, upon a plan entirely new; with a description of the vegetables made use of, and directions for preparing and administering them to cure disease. To which is prefixed A narrative of the life and medical discoveries of the author.

Mode of access: Internet.

The vegetable system : or, a series of experiments, and observations tending to explain the internal structure, and the life of plants; their growth, and propagation; the number, proportion, and desposition of their constituent parts; with the true course of their juices; the formation of the embryo, the construction of the seed, and the encrease from that state to perfection /

Vol. 1 is dated 1759, vols. 2-3 1761, vol. 4 1762, and vol. 5 1763.

The complete duty of man: or, A system of doctrinal and practical Christianity. To which are added, forms of prayer and offices of devotion, for the various circumstances of life ...

Mode of access: Internet.

Common sense on chronic diseases, or, A rational treatise on the mechanical cause and cure of most chronic affections of the truncal organs of both male and female systems : embracing the author's views on physical education, and the present popular system of artificial life /

Included in the original collection of the Starling Medical College.