Evolution of the last koninckinids (Athyridida, Koninckinidae), a precursor signal of the early Toarcian mass extinction event in the Western Tethys

Koninckinids are a suitable group to shed light on the biotic crisis suffered by brachiopod fauna in the Early Jurassic. Koninckinid fauna recorded in the late Pliensbachian–early Toarcian from the easternmost Subbetic basin is analyzed and identified as a precursor signal for one of the most conspicuous mass extinction events of the Phylum Brachiopoda, a multi-phased interval with episodes of changing environmental conditions, whose onset can be detected from the Elisa–Mirabile subzones up to the early Toarcian extinction boundary in the lowermost Serpentinum Zone (T-OAE). The koninckinid fauna had a previously well-established migration pattern from the intra-Tethyan to the NW-European basins but a first phase with a progressive warming episode in the Pliensbachian–Toarcian transition triggered a koninckinid fauna exodus from the eastern/central Tethys toward the westernmost Mediterranean margins. A second stage shows an adaptive response to more adverse conditions in the westernmost Tethyan margins and finally, an escape and extinction phase is detected in the Atlantic areas from the mid-Polymorphum Zone onwards up to their global extinction in the lowermost Serpentinum Zone. This migration pattern is independent of the paleogeographic bioprovinciality and is unrelated to a facies-controlled pattern. The anoxic/suboxic environmental conditions should only be considered as a minor factor of partial control since well-oxygenated habitats are noted in the intra-Tethyan basins and this factor is noticeable only in the second westward migratory stage (with dwarf taxa and oligotypical assemblages). The analysis of cold-seep proxies in the Subbetic deposits suggests a radiation that is independent of methane releases in the Subbetic basin.

Catharine Waugh McCullouch papers in the Mary Earhart Dillon collection, 1869-1945

Collection primarily documents McCulloch's research on women's legal status, and her work with the Illinois Equal Suffrage Association, the National American Woman Suffrage Association, and the League of Women Voters. There is also documentation of women in the legal profession, of McCulloch's friendships with the other women suffragists and lawyers, and some biographical material. The papers contain little information about her family or social life.

Catalogue of Chinese rubbings from Field Museum / researched by Hoshien Tchen, M. Kenneth Starr ; prepared by Alice K. Schneider ; photographs by Herta Newton, and Field Museum Division of Photography ; edited by Hartmut Walravens.

n.s. no.3(1981)

Impaired renal endothelial nitric oxide synthase and reticulocyte production as modulators of hypertension induced by recombinant human erythropoietin in the rat

INTRODUCTION AND AIMS: Hypertension is a common side effect of recombinant human erythropoietin (rHuEPO) therapy; however, the exact pathways remain to be elucidated. The discovery of non-hematopoietic actions of rHuEPO increased the number of patients that could putatively benefit from this therapy; however, to achieve those effects higher doses are usually needed, which increase the risk and incidence of adverse events. Our aim was to study the effect of a broad range of rHuEPO doses on hematological and biochemical parameters, blood pressure and renal function and damage in the rat, focusing on endothelial nitric oxide synthase (eNOS) and hypoxia-inducible factors (HIFs). METHODS: Male Wistar rats were divided in 5 groups receiving different doses of rHuEPO (100, 200, 400 and 600 IU/kg body weight (BW)/week) and saline solution (control), during 3 weeks. Blood and 24h urine were collected to perform hematological and biochemical analysis. Blood pressure (BP) was measured by the tail-cuff method. The kidney tissue was collected to mRNA and protein expression assays and to characterize renal lesions. RESULTS: A dose-dependent increase in red blood cells count, hematocrit and hemoglobin levels was found with rHuEPO therapy, in rHuEPO200, rHuEPO400 and rHuEPO600 groups. Increased reticulocyte count was found in the rHuEPO400 and rHuEPO600 groups. BP raised in all groups receiving rHuEPO. The rHuEPO200 and rHuEPO600 groups presented increased kidney protein levels of HIF2α and a reduction in kidney protein levels of eNOS, along with the highest grade of vascular and tubular renal lesions. CONCLUSIONS: Our study showed that rHuEPO-induced hypertension might involve indirect (hematological) and direct (renal) effects which varies according to the dose used. Thus, rHuEPO therapy should be performed rationally and under adequate surveillance, as hypertension develops even with lower doses. Especial caution with higher doses should be taken, as rHuEPO-induced hypertension leads to early renal damage without alterations in traditional markers of renal function, thus masking the serious adverse effects and risks.

Identification of genetic determinants associated with susceptibility and therapeutic efficacy in Philadelphia-negative Myeloproliferative Neoplasms

Poster presented at the Scientific Toxomics Meeting, 28 September 2015, Lisbon, Portugal.

Index to subject bibliographies in library bulletins to December 31, 1897.

Mode of access: Internet.

The car of destiny and its errand in Spain /

Mode of access: Internet.

A singer in the outer court; a collection of songs and verses.

Mode of access: Internet.

Alice, an adultery.

"...slightly abridged from the privately issued first edition...."

The new American cook book : containing thousands of recipes, practical suggestions and methods for the household contributed by celebrated chefs and more than two hundred experienced housekeepers, who are recognized authorities in the culinary art, and covering every branch of cookery : with special directions for serving at table, also preserving, pickling, candy-making, etc. : presenting the most healthful, palatable, economical and approved use of the foods of the twentieth century.

Includes indexes.

A holy, sacred, and divine roll and book from the Lord God of Heaven, to the inhabitants of earth : revealed in the United Society at New Lebanon, County of Columbia, State of New-York, United States of America : read and understand all ye in mortal clay : in two parts /

Part I: vii, 222, [4] p.; part II: [4], 223-402, [4] p.

"All's well", or, Alice's victory /

Mode of access: Internet.

The library of home economics : a complete home-study coursr on the new profession of home-making and art of right living : the practical application of athe most recent advances in the arts and sciences to home and health /

v.1. The house, its plan, decoration and care / by Isabel Bevier. -- v.2. Household bacteriology / by S. Maria Elliott. -- v.3. Household hygiene / by S. Maria Elliott. -- v.4. Chemistry of the household / by Margaret E. Dodd. -- v.5. Principles of cookery / by Anna Barrows. -- v.6. Food and dietetics / by Alice P. Norton. -- v.7. Household management by Bertha M. Terrill. -- v.8. Personal hygiene / ed. by M. Le Bosquet. -- v.9. Home care of the sick / by Amy E. Pope. -- v.10. Textiles and clothing / by Kate H. Watson. -- v.11. Study of child life / by Marion F. Washburne. -- v.12. Care of children / by A.C. Cotton.

The traditional games of England, Scotland, and Ireland, with tunes, singing-rhymes, and methods of playing according to the variants extant and recorded in different parts of the Kingdom;

"List of authorities": v. 1, p. xi-xiv; v. 2, p. vii-ix.

Home life in colonial days /

Disbound Original Held in Oak Street Library Facility.