Niagara Falls/Niagara Power, 1792, 1798, 1829, 1832, 1836, 1838, 1848, 1852-1853, 1855, 1859, 1871, 1873, 1875-1876, 1878, 1880-1881, 1883, 1885-1888, 1890-1909, 1916-1917, n.d.

A finding aid for collection RG 86. This archive contains materials relating to Niagara Falls and its development during the late 19th and early 20th century, with particular focus on power operations.

Last Will and Testament of David Brooks, 1822

David Brooks was the acting quarterman of shipwrights in his Majesty’s Dock Yard in Portsmouth. He resided at Ridge Street Halfway Houses in Portsea. He was married to Sally Brooks, who was the daughter of Will Thomas Baker of Kent County. Mr. Baker died on May 11, 1811. David and Sally had 5 children: David, Charles, Thomas, Sarah Ann and Hannah Baker. Mr. Brooks bequeathed all his possessions to his wife Sally. After his wife’s death he wanted his belongings and land to be divided equally between all of his children when they reached the age of 21. He names his wife Sally, and his brother, Isaac Brooks as executors of the will.

School Board report, Bertie Township, January 13, 1848

Dexter Deverardo settled in the Niagara District around 1834. In 1842, he was elected to the District Council. He served in this position until around 1848, when he became Superintendent of Education for the Niagara District. He subsequently served as county Registrar (appointed in1852), Registrar of the Surrogate Court for Welland (1856), and served as county clerk until 1873.

Novel glutathione disulfide transferase function of CC-glutaredoxins involved in disease resistance and flower development

Glutaredoxins are oxidoreductases capable of reducing protein disulfide bridges and glutathione mixed disulfides through the process of deglutathionylation and glutathionylation. Lately, redox-mediated modifications of functional cysteine residues of TGA1 and TGA8 transcription factors have been postulated. Namely, GRX480 and ROXY1 glutaredoxins have been previously shown to interact with TGA proteins and have been suggested to regulate redox state of these proteins. TGA1, together with TGA2, is involved in systemic acquired resistance (SAR) establishment in the plant Arabidopsis thaliana through PR1 (Pathogenesis related 1) gene activation. They both form an enhanceosome complex with the NPR1 protein (non-expressor of pathogenesis related gene 1) which leads to PR1 transcription. Although TGA1 is capable of activating PR1 transcription, the ability of the TGA1 NPR1 enhanceosome complex to assembly is based on the redox status of TGA1. We identified GRX480 as a glutathionylating enzyme that catalyzes the TGA1 glutathione disulfide transferase reaction with a Km of around 20μM GSSG (oxidized glutathione). Out of four cysteine residues found within TGA1, C172 and C266 were found to be glutathionylated by this enzyme. We also confirmed TGA1 glutathionylation in vivo and showed that this modification takes place while TGA1 is associated with the PR1 promoter enzymatically via GRX480. Furthermore, we show that glutathionylation via GRX480 abolishes TGA1's interaction with NPR1 and consequently prevents the TGA1-NPR1 transcription activation of PR1. When glutathionylated, TGA1 is recruited to the PR1 promoter and acts as a repressor. Therefore, glutathionylation is a mechanism that prevents TGA1 NPR1 interaction, allowing TGA1 to function as a repressor of PR1 transcription. Surprisingly, GRX480 was not able to deglutathionylate proteins demonstrating the irreversible nature of the reaction. Moreover, we demonstrate that other members of CC-class glutaredoxins, namely ROXY1 and ROXY2, can also catalyze protein glutathionylation. The TGA8 protein was previously shown to interact with NPR1 analogs, BOP1 and BOP2 proteins. However, unlike the case of TGA1 NPR1 interaction, here we demonstrate that TGA8-BOP1 interaction is not redox regulated and that TGA8 glutathionylation by ROXY1 and ROXY2 enzymes does not abolish this interaction in vitro. However, TGA8 glutathionylation results in TGA8 oligomer disassembly into smaller complexes and monomers. Our results suggest that CC-Grxs are unable to reduce mixed disulfides, instead they efficiently catalyze the opposite reaction which distinguishes them from traditional glutaredoxins. Therefore, they should not be classified as glutaredoxins but as protein glutathione disulfide transferases.

Liquor License - Montreal, 1805

A license to sell liquor in Montreal in the year 1805. The license is for Jean Baptiste Bureau and is signed by Lieutenant Governor of the Province of Lower-Canada, Robert S. Milnes.

Place Card - Girl in Blue Dress with Flower

A place card with an illustration of a girl in a blue dress and red flowers.

Place Card - Girl in Green Dress with Flower

A place card with an illustration of a girl in a green dress and red flowers.

Indenture between Captain Thomas Bushby and Sarah Bushby and Edward Clarke Campbell

Indenture of bargain and sale between Captain Thomas Bushby of the Island of Jersey and his wife Sarah Bushby to Edward Clarke Campbell of the town of Niagara regarding 100 acres in Sherbrooke Forest in the District of Niagara, also Lots 6 and 7 in the town plot of Sherbrooke. This document was registered in the Township of Sherbrooke on December 28, 1849 - instrument no. 503, March 17, 1849.

Indenture between Charles Adams and Charles Ira Ames

Indenture of mortgage between Charles Adams of Hamilton and Charles Ira Ames of Hamilton of the first part to Frances Malvinia, wife of Charles Adams of the second part and Thomas Clarke Street of Chippewa, eldest son and heir of Samuel Street of the third part regarding Lot no. 5 in the 5th Concession in the Township of Caradoc in the County of Middlesex, May 5, 1854.

Indenture between Margaret Adams and Samuel DeVeaux Woodruff

Indenture of deed of land by way of quit-claim between Margaret Adams of St. Catharines and Samuel DeVeaux Woodruff of St. Catharines regarding parts of Lots no. 20 and 21 in the 5th and 6th Concessions in the Township of Grantham. This was registered in the Lincoln County Registry on January 21, 1875 - instrument no. 2053 and instrument no. 4819, January 20, 1875.

Indenture between George Adams, George Peirce and Julia P. Peirce to Samuel DeVeaux Woodruff

Indenture of deed of land situate between George Adams, George Peirce and Julia P. Peirce, all of St. Catharines to Samuel DeVeaux Woodruff of St. Catharines regarding parts of Lots no. 20 and 21 in the 5th and 6th Concessions in the Township of Grantham. This was registered in the Lincoln County Registry on January 21, 1845 - instrument no. 1818 and instrument no. 2052, January 20, 1875.

Niagara Falls Handbill Collection, 1838-1886, n.d. (non-inclusive)

According to legend, the Burning Springs were discovered by early natives in the Niagara Peninsula. Bridgewater Mills was built on the site of the spring. During the excavation of the factory; workmen uncovered the spring. Samuel Street and Thomas Clark recognized the potential of this as a tourist attraction so they built a wooden shelter over the spring. The spring was covered with a barrel with a pipe protruding from it. This became the first tourist attraction at Niagara. The Cave of the Winds was a cavern located behind the Bridal Veil Fall. It was originally named the Aeolus Cave. In 1920, a sudden rock fall from the ceiling killed 3 tourists. The cave was destroyed in 1955 as it was deemed dangerous. The captain of the Maid of the Mist was usually a farmer who owned the land where the ship docked. In 1846, the first steam powered Maid of the Mist was launched. By 1848, the first suspension bridge was built over the gorge and the main purpose of the Maid of the Mist was no longer to carry people who needed to travel, but now the focus was on people who wanted to view the Falls at close range. Source: http://www.niagarafrontier.com/burningsprings.html http://www.niagarafrontier.com/winds.html http://reservationsystems.com/niagara_daredevils/maid_of_the_mist.html

Letter to Robert F. Nelles from Adams and Co.

Letter to Robert F. Nelles from Adams and Co. of Boston stating that they knew Jesse Haycock when he lived in that city. Most of the letter is water damaged and text is very much affected. This is accompanied by an envelope which is also very fragile and water damaged, but the address and return address are legible, Mar. 8, 1851.

Marriage Bond between Henry Chambers of Ancaster and Sarah Smith of Ancaster

Marriage Bond between Henry Chambers of Ancaster and Sarah Smith of Ancaster signed by Charles Anderson of Grimsby and Robert F. Nelles of Grimsby, Dec. 27, 1836.

Marriage Bond between Thomas A. Allen of Grimsby and Sarah Bridgeman of Grimsby

Marriage Bond between Thomas A. Allen of Grimsby and Sarah Bridgeman of Grimsby signed by Adam Duff of Grimsby and Palmer Bugbee [Buckbee] of Grimsby, Sept. 28, 1838.