Bionomy of two flies of sanitary and forensic importance: Peckia (Sarcodexia) lambens (Wiedemann) and Oxysarcodexia amorosa (Schiner) (Diptera, Sarcophagidae)

ABSTRACTThis study aims to elucidate the bionomy of Peckia(Sarcodexia) lambens and Oxysarcodexia amorosa to provide data for medical, veterinary and forensic entomology analyses. We analyzed larval stage duration (L1–L3), weight of the mature larvae (L3), pupal stage duration, L1–adult duration, adult emergence and viability of larvae and adults of both species. Larval viability of P. (S.) lambens was 82% and the mean duration of the larval stage was 3.51 ± 0.99 days. The mature larvae had a mean weight of 33.67 ± 7.13 mg. The mean duration of the pupal stage was 8.26 ± 0.93 days and the mean duration of the L1–adult was 11.53 ± 1.22 days. Mean lifespan for females and males was 39.33 ± 1.52 and 57.33 ± 4.72 days, respectively. Larval viability of O. amorosa was 76% and mean duration of larval stage was 3.51 ± 0.64 days. Mature larvae had a mean weight of 28.28 ± 3.38 mg. Mean duration of the pupal stage was 10.14 ± 0.63 days and mean duration of the L1–adult was 13.60 ± 0.69 days. Mean lifespan for females and males was 83.66 ± 15.94 and 84.00 ± 19.97 days, respectively. Oxysarcodexia amorosa showed a L1–adult stage longer than P. (S.) lambens; however both species showed low viability. O. amorosa laid more larvae than P. (S.) lambens, this fact may occur because O. amorosa had longer life duration.

Maisteri Irma Karvikko 21/9 1959

Kirje 21.9.1959

Distribución y abundancia de huevos de anchoveta en un área seleccionada (7°-9°S). Crucero BIC Jose Olaya Balandra 9908-09

Se dan a conocer los resultados obtenidos durante la prospección para la evaluación de la abundancia de huevos de anchoveta en área seleccionada a bordo del Crucero.

Fitoplancton en el invierno 1999 en un área seleccionada (7°-9°S). Crucero BIC Jose Olaya Balandra 9908-09

Se realiza una caracterización cualitativa y cuantitativa del fitoplancton en el área comprendida entre Pimentel y Chimbote

Aspectos biológicos pesqueros de recursos pelágicos en un área seleccionada (7°-9°). Crucero BIC Jose Olaya Balandra 9908-09

El crucero tuvo como objetivo fundamental determinar la abundancia, distribución y concentración de huevos y larvas de anchoveta.

Distribución y biomasa de anchoveta y viciguerria durante el invierno 1999. Crucero BIC Jose Olaya Balandra 9908-09

Se utilizó la tecnología hidroacústica para conocer la distribición y biomasa de los recursos pelágicos.

Biomassa microbiana de carbono e de nitrogênio de solos sob diferentes coberturas florestais

O método da fumigação-extração foi utilizado para estimar a biomassa microbiana de carbono (BM-C) e de nitrogênio (BM-N) de um latossolo vermelho-amarelo, sob diferentes coberturas florestais, na região de Viçosa (MG), em amostras de solos coletadas em abril de 1994. Os solos sob eucalipto e pinheiro apresentaram valores maiores de BM-C (223,72 e 207,39 mg kg-1 de C no solo respectivamente) do que os solos sob angico e capoeira (82,94 e 79,47 mg kg-1 de C no solo respectivamen-te). Resultados semelhantes foram obtidos para a serapilheira acumulada. Por outro lado, a taxa de respiração específica da biomassa microbiana (TR-BM) foi maior no solo sob angico e capoeira. A BM-N variou de 8,05 a 16,08 mg kg-1 de N no solo entre as coberturas florestais. A TR-BM apresentou correlação negativa significativa com o N total do solo (r = -0,76**) e com a serapilheira acumulada (r = -0,68*). BM-N apresentou correlação negativa significativa com o N da serapilheira (r = -0,52*) e com o N mineral do solo (r = -0,71*). BM-C, BM-N e respiração acumulada (RA) foram positivamente correlacionadas com o C orgânico (r = 0,63*, r = 0,71* e r = 0,76* respectivamente). O N total correlacionou-se com BM-C e RA (r = 0,77* e r = 0,60* respectivamente). BM-C e BM-N, associadas aos teores de C orgânico, N-total e TR-BM, mostraram ser indicadores sensíveis para aferir a dinâmica desses elementos sob as coberturas vegetais estudadas, mostrando o menor potencial de decomposição da matéria orgânica nos solos sob eucalipto e pinheiro.

Estructura del subsistema demersal durante el verano 2004.Crucero BIC Olaya 0401-02.

El Crucero BIC Olaya 0401-02 se efectuó del 14 enero al 7 febrero 2004, de Puerto Pizarro (3°29’S) a Punta Pacasmayo (7°23’S). Se utilizó la red de arrastre Granton 300/160. Se efectuaron 87 arrastres de fondo, la captura total fue 42.015,8 kg, constituida por 169 especies: peces (102), crustáceos (32), moluscos (21), equinodermos (9), cnidarios (4) y anélidos (1). Las especies más importantes fueron: merluza peruana, Merluccius gayi peruanus (31.429,42 kg; 75% del total); bereche con barbo, Ctenosciaena peruviana (2815,67 kg; 6,7%); pota, Dosidicus gigas (1.777,27 kg; 4,2%); lenguado ojón, Hippoglossina macrops (611,82 kg; 1,5%); chiri Peprilus medius (543,67 kg; 1,3%); y el pampanito, Peprilus snyderi (497,54 kg; 1,2%). En conjunto, estas seis especies, representaron el 90% del monto total. Esta diversidad es similar al verano 2003 y también la distribución de los peces, cuya mayor diversidad específica se encontró al norte de Punta Aguja (6°S), indicando condiciones de normalidad.

El fitoplancton de invierno en el crucero de estimación de biomasa de anchoveta 0708-09

Los volúmenes de plancton superficial fluctuaron entre 0,06 y 11,14 mL.m-3 localizados frente a Pisco y Paita, respectivamente, registrando un promedio general de 1,34 mL.m-3. El fitoplancton en superficie predominó en el 31% del área evaluada. El microplancton estuvo caracterizado por diatomeas pequeñas de afloramiento (Chaetoceros sociales, Ch. compressus, Ch. lorenzianus, Skeletonema costatum) y por especies de la fase intermedia de la sucesión (Coscinodiscus perforatus, C. centralis, Thalassionema frauenfeldii, Lithodesmium undulatum). La presencia de especies termófilas también fue representativa encontrándose cerca y lejos de la costa, destacando por su abundancia las diatomeas Planktoniella sol, Proboscia alata f. gracillima y Thalasiothrix longissima. La correlación significativa entre la biomasa planctónica y oxígeno (r=>0,5) sugirió una mayor actividad autotrófica en las zonas norte y sur. El indicador de ACF, Protoperidinium obtusum, presentó una distribución costera con una amplitud máxima hasta las 120 mn al sur de Chicama y Atico y C. praelongum indicador de ASS sólo fue registrado a 70 mn frente a Pucusana.

Isla Lobos de Tierra: Evaluación de invertebrados en bancos naturales, 2010

Las tallas de Transennella pannosa fluctuaron entre 10 y 34 mm de altura valvar, con media en 27,2 mm; predominaron ejemplares maduros (55,56%) y en evacuación (27,78%); se distribuyó entre 6°25’46,6’’S y 6°27’24,8’’S, en concentraciones de 4478 ind.m-2, la biomasa estimada fue 1566,7 t y la población 248,4 millones de ejemplares. La talla de Pollicipes elegans varió entre 6 y 40 mm de longitud carina rostral, media 26,2 mm; los juveniles (Lcr<17 mm) fueron el 11,63% y los adultos (Lcr≥17 mm) el 88,37%; predominaron ejemplares maduros (72,09%). La talla de Argopecten purpuratus varió entre 9 y 82 mm de altura valvar, media de 56,7 mm; los juveniles (<25 mm) fueron el 0,41% y los adultos comerciales (≥65 mm) el 15,27%; predominaron los desovantes (73,62%); se distribuyó entre 6°21’54,8’’S y 6°25’33,6’’S con concentraciones absolutas de 1 a 121 ejem.m-2 en profundidades de 6,2 a 24,9 m. Las tallas de Octopus mimus fluctuaron entre 100 y 200 mm de longitud del manto; en hembras predominó madurez total y post-fresa, ambos con 40%.

RNOP-09: pegylated liposomal doxorubicine and prolonged temozolomide in addition to radiotherapy in newly diagnosed glioblastoma--a phase II study.

BACKGROUND: Although Temozolomide is effective against glioblastoma, the prognosis remains dismal and new regimens with synergistic activity are sought for. METHODS: In this phase-I/II trial, pegylated liposomal doxorubicin (Caelyx, PEG-Dox) and prolonged administration of Temozolomide in addition to radiotherapy was investigated in 63 patients with newly diagnosed glioblastoma. In phase-I, PEG-Dox was administered in a 3-by-3 dose-escalation regimen. In phase-II, 20 mg/m2 PEG-Dox was given once prior to radiotherapy and on days 1 and 15 of each 28-day cycle starting 4 weeks after radiotherapy. Temozolomide was given in a dose of 75 mg/m2 daily during radiotherapy (60 Gy) and 150-200 mg/m2 on days 1-5 of each 28-day cycle for 12 cycles or until disease progression. RESULTS: The toxicity of the combination of PEG-Dox, prolonged administration of Temozolomide, and radiotherapy was tolerable. The progression free survival after 12 months (PFS-12) was 30.2%, the median overall survival was 17.6 months in all patients including the ones from Phase-I. None of the endpoints differed significantly from the EORTC26981/NCIC-CE.3 data in a post-hoc statistical comparison. CONCLUSION: Together, the investigated combination is tolerable and feasible. Neither the addition of PEG-Dox nor the prolonged administration of Temozolomide resulted in a meaningful improvement of the patient's outcome as compared to the EORTC26981/NCIC-CE.3 data.

Primary mucosa-associated lymphoid tissue lymphoma of the salivary glands: a multicenter Rare Cancer Network study.

Purpose: Involvement of salivary glands with mucosa-associated lymphoid tissue (MALT) lymphoma is rare. This retrospective study was performed to assess the clinical profile, treatment outcome, and prognostic factors of MALT lymphoma of the salivary glands.Methods and Materials: Thirteen member centers of the Rare Cancer Network from 10 countries participated, providing data on 63 patients. The median age was 58 years; 47 patients were female and 16 were male. The parotid glands were involved in 49 cases, submandibular in 15, and minor glands in 3. Multiple glands were involved in 9 patients. Staging was as follows: IE in 34, IIE in 12, IIIE in 2, and IV in 15 patients.Results: Surgery (S) alone was performed in 9, radiotherapy (RI) alone in 8, and chemotherapy (CT) alone in 4 patients. Forty-one patients received combined modality treatment (S + RT in 23, S + CT in 8, RT + CT in 4, and all three modalities in 6 patients). No active treatment was given in one case. After initial treatment there was no tumor in 57 patients and residual tumor in 5. Tumor progression was observed in 23 (36.5%) (local in 1, other salivary glands in 10, lymph nodes in 11, and elsewhere in 6). Five patients died of disease progression and the other 5 of other causes. The 5-year disease-free survival, disease-specific survival, and overall survival were 54.4%, 93.2%, and 81.7%, respectively. Factors influencing disease-free survival were use of RI, stage, and residual tumor (p < 0.01). Factors influencing disease-specific survival were stage, recurrence, and residual tumor (p < 0.01).Conclusions: To our knowledge, this report represents the largest series of MALT lymphomas of the salivary glands published to date. This disease may involve all salivary glands either initially or subsequently in 30% of patients. Recurrences may occur in up to 35% of patients at 5 years; however, survival is not affected. Radiotherapy is the only treatment modality that improves disease-free survival. (C) 2012 Elsevier Inc.

A pilot assessment of alpha-stat vs pH-stat arterial blood gas analysis after cardiac arrest.

PURPOSE: Resuscitated cardiac arrest (CA) patients typically receive therapeutic hypothermia, but arterial blood gases (ABGs) are often assessed after adjustment to 37°C (alpha-stat) instead of actual body temperature (pH-stat). We sought to compare alpha-stat and pH-stat assessment of Pao2 and Paco2 in such patients. MATERIALS AND METHODS: Using ABG data obtained during the first 24 hours of intensive care unit admission, we determined the impact of measured alpha vs calculated pH-stat on Pao2 and Paco2 on patient classification and outcomes for CA patients. RESULTS: We assessed 1013 ABGs from 120 CA patients with a median age of patients 66 years (interquartile range, 50-76). Median alpha-stat Pao2 changed from 122 (95-156) to 107 (82-143) mm Hg with pH-stat and median Paco2 from 39 (34-46) to 35 (30-41) mm Hg (both P < .001). Using the categories of hyperoxemia, normoxemia, and hypoxemia, pH-stat estimation of Pao2 reclassified approximately 20% of patients. Using the categories of hypercapnia, normocapnia, and hypocapnia, pH stat estimation of Paco2 reclassified approximately 40% of patients. The mortality of patients in different Pao2 and Paco2 categories was similar for pH-stat and alpha-stat. CONCLUSIONS: Using the pH-stat method, fewer resuscitated CA patients admitted to intensive care unit were classified as hyperoxemic or hypercapnic compared with alpha-stat. These findings suggest an impact of ABG assessment methodology on Pao2, Paco2, and patient classification but not on associated outcomes.

Association of the hemochromatosis gene with pazopanib-induced transaminase elevation in renal cell carcinoma.

BACKGROUND & AIMS: Pazopanib has demonstrated clinical benefit in patients with advanced renal cell carcinoma (RCC) and is generally well tolerated. However, transaminase elevations have commonly been observed. This 2-stage study sought to identify genetic determinants of alanine transaminase (ALT) elevations in pazopanib-treated white patients with RCC.¦METHODS: Data from two separate clinical studies were used to examine the association of genetic polymorphisms with maximum on-treatment ALT levels.¦RESULTS: Of 6852 polymorphisms in 282 candidate genes examined in an exploratory dataset of 115 patients, 92 polymorphisms in 40 genes were significantly associated with ALT elevation (p<0.01). Two markers (rs2858996 and rs707889) in the HFE gene, which are not yet known to be associated with hemochromatosis, showed evidence for replication. Because of multiple comparisons, there was a 12% likelihood the replication occurred by chance. These two markers demonstrated strong linkage disequilibrium (r(2)=0.99). In the combined dataset, median (25-75th percentile) maximum ALT values were 1.2 (0.7-1.9), 1.1 (0.8-2.5), and 5.4 (1.9-7.6)×ULN for rs2858996 GG (n=148), GT (n=82), and TT (n=1 2) genotypes, respectively. All 12 TT patients had a maximum ALT>ULN, and 8 (67%) had ALT≥3×ULN. The odds ratio (95% CI) for ALT≥3×ULN for TT genotype was 39.7 (2.2-703.7) compared with other genotypes. As a predictor of ALT≥3×ULN, the TT genotype had a negative predictive value of 0.83 and positive predictive value of 0.67. No TT patients developed liver failure.¦CONCLUSIONS: The rs2858996/rs707889 polymorphisms in the HFE gene may be associated with reversible ALT elevation in pazo-panib-treated patients with RCC.