Motor Vehicle Crash Fatalities for Week Ending, January 15, 2010

Motor Vehicle Crash Fatalities

Campagne des Français, depuis le 8 septembre 1793, répondant au 22 fructidor de l'an 1er de la République française, jusqu'au 15 pluviôse an III

[Acte. 1795-02-03]

EPI Update, January 15, 2010

Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public Health.

Adenosquamous carcinoma of the head and neck: report of 20 cases and review of the literature.

PURPOSE: To assess the clinical profile and prognostic factors in patients with adenosquamous carcinoma (ASC) of the head and neck treated by surgery and/or radiation therapy with or without chemotherapy. METHODS: Data from 20 patients with stage I-II (n = 4), III (n = 5), or IVA (n = 11) head and neck ASC, treated between 1989 and 2010 were collected in a retrospective multicenter Rare Cancer Network study. Surgery was performed in 16 patients. Seventeen patients received combined modality treatment. RESULTS: After a median follow-up of 15.5 months, 12 patients recurred. The 3-year and median overall survival, disease-free survival (DFS), and loco-regional control were 52% and 39 months, 32% and 12 months, and 47% and 33 months respectively. In multivariate analysis, DFS was negatively influenced by the presence of extracapsular extension and advanced stage. CONCLUSION: Overall prognosis of locoregionally advanced ASC remains poor. However, early stage ASC patients managed with combined modality treatment may have prolonged DFS.

Effect of conditioned media, nutritive elements, and mitotic synchronization on the accuracy of the cytogenetic analysis in acute nonlymphocytic leukemia patients presenting with inv(16)/t(16;16) or t(15;17).

To improve the yield of the cytogenetic analysis in patients with acute nonlymphocytic leukemia (ANLL), six culture conditions for bone marrow or peripheral blood cells were tested in parallel. Two conditioned media (CM), phytohemagglutinin leukocyte PHA-LCM and 5637 CM, nutritive elements (NE), and methotrexate (MTX) cell synchronization were investigated in 14 patients presenting with either inv(16)/ t(16;16) (group 1, n = 9 patients) or t(15;17) (group 2, n = 5). The criteria used to identify the most favorable culture conditions were the mitotic index (MI), the morphological index (MorI), and the percentage of abnormal metaphases. In the presence of PHA-LCM and 5637 CM, the MI were significantly increased in group 2, whereas in the MTX conditions, MI remained very low in both groups. The values of the MorI did not reveal any significant changes in chromosome resolution between the conditions in either group. The addition of NE did not have a positive effect in quantity or quality of metaphases. Because of the variability of the response of leukemic cells to different stimulations in vitro, several culture conditions in parallel are required to ensure a satisfactory yield of the chromosome analysis in ANLL.

Administrative Transition Planning Notebook, November 15, 2006

Seven Years ofInnovation, Technological Advances, Enhanced Service & Fluid Commerce in the Iowa Alcoholic Beverages Division.

Fiscal Update, March 15, 2010

The Fiscal Division newsletter, published weekly during session and periodically during the interim.

Iowa Workforce Monthly, April 2010, Issue 15

Highlights: *YouTube and Twitter.....................pg. 2 Stay up-to-date on all the training opportunities available in your area.............................................pg. 2 * RES Success Story: In January, Johanna Hofmeister attended Re-Employment Services (RES) training......................pg. 2 * We are three weeks into the My Iowa UI presentation schedule and response has been tremendous..............................pg. 3 * In 2009, IWD Employees raised over $7,200 for the Toys for Tots program............pg. 3