991 resultados para Saturation Impulse


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This paper assesses empirically the effect of oil price shocks on Portuguese aggregate economic activity, industrial production and price level. We take the usual multivariate VAR methodology to investigate the magnitude and stability of this relationship. In doing so, we follow the approach presented in the recent literature and adopt different oil price specifications. We conclude that, as for most industrialized countries, the nature of this relationship changed in the mid-1980s. Furthermore, we show that the main Portuguese macroeconomic variables have become progressively less responsive to oil shocks and the adjustment towards equilibrium has become increasingly faster.

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A Work Project, presented as part of the requirements for the Award of a Masters Degree in Management from the NOVA – School of Business and Economics

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Dissertação para obtenção do Grau de Doutor em Alterações Climáticas e Políticas de Desenvolvimento Sustentável

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The medical records of 27 patients with hantavirus pulmonary syndrome were analyzed according to the need for invasive mechanical ventilation in relation to the following data up on hospital admission: age, gender, fever, cough, dyspnea, systolic arterial blood pressure, heart rate, levels of hemoglobin, hematocrit, leukocytes, lymphocytes, platelets, creatinine and arterial blood gases. The volume infused during the first 24 hours after admission, the use of inotropic agents, the use of corticosteroids and the patient outcomes were also evaluated. A favorable outcome was related to systolic blood pressure³ 100mmHg, heart rate lower than 100 beats per minute, creatinine below 1.6mg/dl, arterial blood pH³ 7.35, bicarbonate higher than 15mEq/dl, oxygen saturation higher than 84.1%, lower rehydration volume in the first 24 hours of hospitalization and no use of inotropic agents. Absence of clinical and laboratory signs of circulatory shock up on admission was associated with a favorable outcome of the patients.

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RESUMO: O envelhecimento da população é um fenómeno à escala mundial, com tendência a aumentar, sendo cada vez mais os idosos e mais velhos. Esta propensão é notória nos utentes que recorrem aos cuidados de saúde. À medida que se envelhece maior vai sen-do a vulnerabilidade e riscos para a saúde, bem como a prevalência para doenças croni-cas, que se traduz num aumento de hospitalizações e consumo. As complicações ocorri-das em idosos aquando submetidos a intervenções cirúrgicas estão descritas na literatu-ra, havendo uma escassez de publicações nacionais relacionadas com o tema. O presente estudo teve por objectivo caracterizar idosos submetidos a correcção cirúrgi-ca de hérnias da parede abdominal, os procedimentos e as complicações ocorridas. O estudo, transversal e de natureza quantitativa, foi realizado no Centro Hospitalar de Lisboa Norte – Hospital Pulido Valente, e teve como critério de inclusão os indivíduos com 65 ou mais anos submetidos a correcção cirúrgica de hérnias da parede abdominal, realizadas em 2009-2010, que tiveram um período de recobro na Unidade de Cuidados Anestésicos Pós-operatórios. Para a obtenção dos dados, foram analisados os processos clínicos do Arquivo Clínico da Instituição e registada informação sobre variáveis de caracterização sócio demográfi-ca, de saúde pré, intra e pós-operatória imediata e descritivas da cirurgia. Foram avaliadas as situações de 164 indivíduos, 78.7% eram homens e 21.3% mulheres e a média de idades era de 72.4 anos e desvio padrão 5.46. Em termos de hábitos de Vida, foi possível constatar um predomínio de baixo consumo de tabaco (13.4%) e álcool (6.7%). O valor médio de co-morbilidades foi de 2.6 e desvio padrão de 1.34 sendo a maior prevalência de 3-4 co-morbilidades com 48.8%. Salienta-se que todas as mulheres da amostra apresentaram doenças. As patologias mais prevalentes são as do foro cardiovascular: Hipertensão Arterial (75.0%), Dislipidémia (35.4%) e Insuficiência Venosa Periférica (14.6%), de forma menos expressiva, mas igualmente relevante a Diabetes Mellitus (23.8%). Nos mais idosos [75 ou mais], verificou-se uma expressivi-dade Hipertrofia benigna da próstata (18.2%). Das cirurgias ocorridas predominou a correcção cirúrgica de Hérnia Inguinal.Das complicações identificadas prevaleceu a dor (97.6%). A hipotermia (34.8%), HTA (24.4%) e bradicárdia (14.6%) encontram-se entre as complicações mais determinantes. Verificaram-se diferenças com significado estatístico entre os dois grupos etários consi-derados nas complicações bradicárdia (p=0.021) e a saturação de oxigénio <90% (p = 0.006), hemorragia (p=0.036) e retenção urinária (p = 0.038). Neste estudo constata-se que a cirúrgica de hérnias da parede abdominal em idosos é uma realidade prevalente. Dos factores que possam estar associados a propensão para complicações pós-cirúrgicas, a idade e a presença de co-morbilidade controlada não revelaram ter influência. Também os tempos de cirurgia e de anestesia não revelaram influências no surgimento de complicações. A monitorização dos sinais vitais deve ser constante, desde o período pré-operatório imediato de forma a permitir aos profissionais de saúde identificar uma propensão para vulnerabilidade, com vantagem em ser apre-sentado sob a forma de score. Este manifestou diferenças significativas a nível dos dois grupos etários considerados (p=0.001). Este score, vai possibilitar sinalizar quais os idosos com maior susceptibilidade de ocorrência de complicações.------------------ABSTRACT:Population aging has become a worldwide phenomenon with tendency to increase. This is particularly evident due to the amount of elderly that attend the medical services. As one gets older, more vulnerable and more risks to one’s health. Also chronic diseas-es are more likely to exist which lead to more hospitalizations and increase of consuma-bles. The complications after a surgery in older people are well documented in international scientific studies, however national studies are still lacking. The present study aims to characterize elderly patients after abdominal hernia surgical correction, the procedures and complications detected. This transversal and quantitative nature like study, was held in the Centro Hospitalar Lisboa-Norte – Hospital Pulido Valente, and as inclusive criteria where patients with more than 65 or more years old, who undergone abdominal hernia surgical correction surgery in 2009-2010 and had the post-operation on the Unidade de Cuidados Anestésicos Pós-Operatorios. Data from the clinical files from the archive of the hospital where analyzed. Information was taken regarding social demographic variables; before, during and immediately after surgery variables and also descriptive of the surgery itself. Were evaluated 164 individuals, 78, 7% of which were men and 21, 3% women with an average age of 72, 4 years and standard deviation 5.46. Life habits analyzed detected low consumption of tobacco (13, 4%) and alcohol (6, 7%). The average of co-morblity was 2, 6 and standard deviation 1.34. The biggest prevalence of 3-4 co-morbilities was 48, 8%. Important to notice that, all women from the study presented illnesses. The illnesses more frequent were cardiovascular: High Blood Pressure (75%), Dyslipidemia (35, 4%), Deep Venous Insufficiency (14, 6%), less significant but also relevant, Diabetes Melli-tus (23, 8%). In the older (75 or more), was noticed Benign Prostatic (18, 2%). In the surgeries verified, the abdominal hernia correction was more frequent. From all thecomplications identified, pain was 97, 6%, Hypothermia 34, 8%, high Blood Pressure 24, 4% and Bradycardia 14, 6%, were higher prevalence. Was seen differences in the statistic meaning of the two groups in the Bradycardia com-plications (p=0.021), and the oxygen saturation < 90% (p=0.006), bleeding (p=0,036) and urine retention (p=0,038). In the present study it is evident that the abdominal hernia surgical correction in older population is a common procedure. Of all the factors that might be related with post-operatory complications, age and the presence of controlled co-morbility didn’t reveal relevant. Also, surgical times and duration of anesthesia didn´t seem to be related to complications incidence. Monitoring the vital signs must be constant since the immedi-ate post-operatory to ensure that the professionals can identify any possible vulnerabil-ity, presenting it in a score like way. The score has shown meaningful differences be-tween the two age groups analyzed (p=0,001). This score allows identifying which pa-tients are more likely to suffer complications.

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Water is a limited resource for which demand is growing. Contaminated water from inadequate wastewater treatment provides one of the greatest health challenges as it restricts development and increases poverty in emerging and developing countries. Therefore, the connection between wastewater and human health is linked to access to sanitation and to human waste disposal. Adequate sanitation is expected to create a barrier between disposed human excreta and sources of drinking water. Different approaches to wastewater management are required for different geographical regions and different stages of economic governance depending on the capacity to manage wastewater. Effective wastewater management can contribute to overcome the challenges of water scarcity. Separate collection of human urine at its source is one promising approach that strongly reduces the economic and load demands on wastewater treatment plants (WWTP). Treatment of source-separated urine appears as a sanitation system that is affordable, produces a valuable fertiliser, reduces pollution of water resources and promotes health. However, the technical realisation of urine separation still faces challenges. Biological hydrolysis of urea causes a strong increase of ammonia and pH. Under these conditions ammonia volatilises which can cause odour problems and significant nitrogen losses. The above problems can be avoided by urine stabilisation. Biological nitrification is a suitable process for stabilisation of urine. Urine is a highly concentrated nutrient solution which can lead to strong inhibition effects during bacterial nitrification. This can further lead to process instabilities. The major cause of instability is accumulation of the inhibitory intermediate compound nitrite, which could lead to process breakdown. Enhanced on-line nitrite monitoring can be applied in biological source-separated urine nitrification reactors as a sustainable and efficient way to improve the reactor performance, avoiding reactor failures and eventual loss of biological activity. Spectrophotometry appears as a promising candidate for the development and application of on-line nitrite monitoring. Spectroscopic methods together with chemometrics are presented in this work as a powerful tool for estimation of nitrite concentrations. Principal component regression (PCR) is applied for the estimation of nitrite concentrations using an immersible UV sensor and off-line spectra acquisition. The effect of particles and the effect of saturation, respectively, on the UV absorbance spectra are investigated. The analysis allows to conclude that (i) saturation has a substantial effect on nitrite estimation; (ii) particles appear to have less impact on nitrite estimation. In addition, improper mixing together with instabilities in the urine nitrification process appears to significantly reduce the performance of the estimation model.

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Skypro is a footwear brand targeted at the aviation professionals’ niche market, explored by the Portuguese microenterprise Abotoa Lda..The saturation of the Portuguese market led Skypro to expand to different worldwide countries and to be a footwear supplier of Airlines from the USA, Qatar or Australia, among others. Abotoa aims for its 2014’s exports to represent around 80% of total sales and this Internationalization Plan for Japan represents the possibility of further exploring the Asian market. Japan appears as the 2nd worldwide footwear importer and the 5th footwear consumer, with a high purchasing power – GDP per capita (PPP). This country possesses two enormous Airlines (ANA and JAL) that employ more than 15000 on-board personnel, the world’s 4th busiest Airport in 2013 (Tokyo’s Haneda International Airport) and a geographic structure with more than 6500 islands, implying high frequency of aerial transportation in the medium-run. These aspects make Japan an adequate country to invest in. At the course of this Work Project, trustworthy recommendations are provided for the current state of Abotoa and for the introduction and implementation of this Internationalization Plan. These findings strongly suggest that Skypro should indeed penetrate Japan’s market.

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This work project takes the format of a problem-solving approach suggested by “Impulse Partners”, a French consulting firm. It recommends a way to measure the success of ten startups in the incubators “Starburst” and “Incubator Construction & Energy” and give them strategic guidance. A Balanced Scorecard is elaborated to help incubated startups building up and implementing their strategy. The Scorecard suggests possible initiatives for the startups that are ideally realized with the help of the consulting firm that is steering the incubator. Special attention is drawn to what the startups need to succeed, which typically concerns financing, networking and managing skills.

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To study the macroeconomic effects of unconventional monetary policy across the different countries of the eurozone, I develop an identification scheme to disentangle conventional from non-conventional policy shocks, using futures contracts on overnight interest rates and the size of the European Central Bank balance sheet. Setting these shocks as endogenous variables in a structural vector autoregressive (SVAR) model, along with the CPI and the employment rate, estimated impulse response functions of policy to macroeconomic variables are studied. I find that unconventional policy shocks generated mixed effects in inflation but had a positive impact on employment, with the exception of Portugal, Spain, Greece and Italy where the employment response is close to zero or negative. The heterogeneity that characterizes the responses shows that the monetary policy measures taken in recent years were not sufficient to stabilize the economies of the eurozone countries under more severe economic conditions.

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Fluid management and dosage regimens of drugs in preterm infants should be based on the glomerular filtration rate. The current methods to determine glomerular flitration rate are invasive, time-consuming, and expensive. In contrast, creatinine clearance can be easy obtained and quickly determined. The purpose of this study was to compare plasma creatinine on the third and seventh day of life in preterm newborn infants, to evaluate the influence of maternal creatinine, and to demonstrate creatinine clearance can be used as a reliable indicator of glomerular filtration rate. We developed a prospective study (1994) including 40 preterm newborns (gestational age < 37 weeks), average = 34 weeks; birth weight (average) = 1840 g, in the first week of life. Inclusion criteria consisted of: absence of renal and urinary tract anomalies; O2 saturation 3 92%; adequate urine output (>1ml/kg/hr); normal blood pressure; absence of infections and no sympathomimetic amines in use. A blood sample was collected to determine plasma creatinine (enzymatic method) on the third and seventh day of life and creatinine clearance (CrCl) was obtained using the following equation: , k = 0.33 in preterm infant All plasma creatinine determinations showed normal values [third day: 0.78 mg/dl ± 0.24 (mean ± SD)and seventh day: 0.67 mg/dl ± 0.31 - (p>0.05)]. Also all creatinine clearance at third and seventh day of life were normal [third day: 19.5 ml/min ± 5.2 (mean ± SD) and seventh day: 23.8 ml/min ± 7.3 - (p>0,05)]. All preterm infants developed adequate renal function for their respective gestational age. In summary, our results indicate that, for clinical practice, the creatinine clearance, using newborn length, can be used to estimate glomerular filtration rate in preterm newborn infants.

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This work reports the development of field-effect transistors (FETs), whose channel is based on zinc oxide (ZnO) nanoparticles (NPs). Using screen-printing as the primary deposition technique, different inks were developed, where the semiconducting ink is based on a ZnO NPs dispersion in ethyl cellulose (EC). These inks were used to print electrolyte-gated transistors (EGTs) in a staggered-top gate structure on glass substrates, using a lithium-based polymeric electrolyte. In another approach, FETs with a staggered-bottom gate structure on paper were developed using a sol-gel method to functionalize the paper’s surface with ZnO NPs, using zinc acetate dihydrate (ZnC4H6O4·2H2O) and sodium hydroxide (NaOH) as precursors. In this case, the paper itself was used as dielectric. The various layers of the two devices were characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier Transform Infrared spectroscopy (FTIR), thermogravimetric and differential scanning calorimetric analyses (TG-DSC). Electrochemical impedance spectroscopy (EIS) was used in order to evaluate the electric double-layer (EDL) formation, in the case of the EGTs. The ZnO NPs EGTs present electrical modulation for annealing temperatures equal or superior to 300 ºC and in terms of electrical properties they showed On/Off ratios in the order of 103, saturation mobilities (μSat) of 1.49x10-1 cm2(Vs)-1 and transconductance (gm) of 10-5 S. On the other hand, the ZnO NPs FETs on paper exhibited On/Off ratios in the order of 102, μSat of 4.83x10- 3 cm2(Vs)-1and gm around 10-8 S.

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AuNPs are versatile systems used for different biomedical application including imaging, drug and gene delivery. These systems support the intracellular transport of active molecules, a step that is considered one of the crucial problems in drug delivery. Nevertheless, in order to design optimal multifunctional AuNPs for specific and efficient nanomedicine applications, the mechanism by which AuNPs interact with living cells must be fully understand. The main goal of this work consisted in the assessment of the cellular uptake mechanism of 14 nm spherical AuNPs by A549 cells, through fluorescent spectroscopy and microscopy, in combination with quantitative analysis by ICP-MS. TAMRA labeled AuNPs were characterized by UV-visible and fluorescent spectroscopy and the final hydrodynamic diameter of 22.5 ± 0.33 nm was obtained by DLS. Regarding the cellular uptake studies, the AuNPs presented a fast cellular uptake kinetics reaching a saturation point after 6 hours of incubation in A549 cells. Further investigation concerning the internalization mechanism of this AuNPs was evaluated using specific inhibitors for different endocytic pathways. Optimal inhibition was achieved using chlorpromazine, inhibitor of clathrin-mediated endocytosis, resulting in a 23.5 % inhibition of AuNPs after 1 hour of incubation. This preliminary result obtained by fluorescent spectroscopy suggests that these AuNPs were predominantly uptake by clathrin-mediated endocytosis, meaning that other endocytic pathways must be involved in the cellular uptake of this AuNPs. In what cell viability is concern, the prepared AuNPs and the endocytic inhibitors revealed no significant effect on the cell viability in A549 cell line.

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This report represents four months of study on activities in the public prosecution service at the Local Instance of Setúbal judiciary district, started in September 2014 and completed of the same year. This report was prepared considering all the teachings of criminal law courses and criminal procedural law, doctrine, jurisprudence and all the practical experience experienced with prosecutors. In this context, their traineeship provided contact with different procedural stages: the investigation stage that allowed to understand better the progress of the processing of summary proceedings; the expedient distribution of urgent cases; the investigation stage, as regards the procedural impulse assistant and the accused; and the trial stage. This last phase allowed contact with different types of crimes especially road crimes and the crime of domestic violence. The analysis carried out the summary proceedings in the Public Ministry service would acquire relevant information to explain the incidence of road crimes. Topics will be addressed that were found on stage during the various procedural stages, as the implementation of new judicial map. The relationship between the prosecution and the Criminal Police Bodies was also an issue to be addressed. The work also raises awareness of the issue of archives in order to find out the position of assistant.

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The Santa Tenesinha region in northeaster Mato Grosso has a varied vegetation which is principally hammock pantanal. The flat clayey alluvial ground between the hummocks is coveted with a continuous non-cerrado ground cover dominated by grasses but which harbors sedges and a lange herb flora. No woody plants grow in it. The tops of the 10-20m wide, slightly elliptical hummocks, 1.5-2 m high, 10-40 per hectare, are covered with cerrado plants: herbs, semlshrubs, thin- and thick-stemmed shrubs and low trees. For 4-5 months during the latter part of the rainy season, the regional water table rises to the surface and the ground between the hummocks becomes saturated or floods up to 1.5-2 m deep. The tops of the hummocks almost always remain above high water level. In the dry season the surface soil dries out completely. This alternation of saturation or shallow flooding and dryness, prevents woody plant, growth between the hummocks, and except for a few tolerant species, also prevents woody plant. growth on the lower part of the hummochs. The gallery forests in the pantanal are seasonally flooded more deeply but their soil does not dry out so thonoughly in the dry season so woody plant growth is not prevented.

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Double Degree