Investigation of brain function in neuropsychiatric disorder using multimodal imaging analysis

Otto-von-Guericke-Universität Magdeburg, Fakultät für Naturwissenschaften, Dissertation, 2016

Multimodal Imaging and Choroidal Volumetric Changes After Half-fluence PDT in Central Serous Chorioretinopathy.

PURPOSE The purpose of this study was to identify SD-OCT changes that correspond to leakage on fluorescein (FA) and indocyanine angiography (ICGA) and evaluate effect of half-fluence photodynamic therapy (PDT) on choroidal volume in chronic central serous choroidoretinopathy (CSC). METHODS Retrospective analysis of patients with chronic CSC who had undergone PDT. Baseline FA and ICGA images were overlaid on SD-OCT to identify OCT correlates of FA or ICGA hyperfluorescence. Choroidal volume was evaluated in a subgroup of eyes before and after PDT. RESULTS Twenty eyes were evaluated at baseline, of which seven eyes had choroidal volume evaluations at baseline and 3 months following PDT. SD-OCT changes corresponding to FA hyperfluorescence were subretinal fluid (73%), RPE microrip (50%), RPE double-layer sign (31%), RPE detachment (15%), and RPE thickening (8%). ICGA hyperfluoresence was correlated in 93% with hyperreflective spots in the superficial choroid. Choroidal volume decreased from 9.35 ± 1.99 to 8.52 ± 1.92 and 8.04 ± 1.7 mm(3) (at 1 and 3 months post PDT, respectively, p ≤ 0.001). CONCLUSIONS We identified specific OCT findings that correlate with FA and ICGA leakage sites. SD-OCT is a valuable tool to localize CSC lesions and may be useful to guide PDT treatment. Generalized choroidal volume decrease occurs following PDT and extends beyond PDT treatment site.

Responsive multimodal transportation management strategies and IVHS. Final report.

Federal Highway Administration, Office of Safety and Traffic Operations Research and Development, McLean, Va.

Comanche texts.

Mode of access: Internet.

Haitian Creole: grammar, texts, vocabulary,

"Also appears as Memoir no. 74 of the American Anthropological Association."

Sayula Popoluca texts, with grammatical outline.

Mode of access: Internet.

Authorized or Revised? Sermons on some of the texts in which the Revised version differs from the Authorized.

"The following sermons were preached with one exception in the Temple church."--Pref.

Sumerian lexical texts from the Temple school of Nippur,

"All the tablets here published form part of the Nippur collections now in the University Museum of the University of Pennsylvania."--Pref.

Hidatsa texts /

Mode of access: Internet.

Kalapuya texts. Part I.Santiam Kalapuya ethnologic texts,

Original texts with English translations.

Introduction to Old Church Slavic--Texts.

Mode of access: Internet.

Texts and studies in Jewish history and literature,

Errata slip inserted between p. [vii] and viii of v. 1 and p. [iv] and v of v. 2.

Mathematical cuneiform texts,

Bibliography: p. 152-156.