Uno Two Drei: la televisione nella promozione linguistica per i giovani. Un caso italiano nel contesto europeo.

The aim of this work is to assess the effectiveness of a project carried out in the Autonomous Province of Trento to promote language learning among young people. The project consisted in a television quiz show featuring games in Italian, English and German. Eight classes from five high schools took part in the game show, which was aired between November 2014 and January 2015 by the local channel Trentino TV. Since multilingualism has been part of the European Union policy, legislation and practices for many decades, the first chapter of this dissertation offers an overview of the main EU language education policies which seek to promote language learning among all citizens. It then focuses on the commitment of the EU and its member States to find new strategies to show the benefits of language learning outside formal education, also using both old and new media. Some TV and radio shows on multilingualism broadcast in Italy and in other EU countries are also briefly described. The second chapter is devoted to Uno Two Drei, the quiz show created by the Autonomous Province of Trento and Trentino TV to promote the learning of English and German among students while enhancing their personal growth and development. The role of everyone involved in the project is outlined, as well as the concept and planning phases and the realization stage. The third chapter focuses largely on the impacts of the initiative on the target group, namely 17-year-old students. Opinions of the participants were first collected in January, when a final meeting was held between the organizers and the schools. Since the researcher has managed the German part of the project, in the following months a questionnaire was administered to the 48 students who played in the German team and to their teachers as well. From both the meeting and the questionnaires it has emerged that the main goals of the initiative were achieved: generally speaking, students have been motivated to study languages and learn new things, the bonds between them have been strengthened and their sense of solidarity has been enhanced.

Il sottotitolaggio per i film festival: due esperienze pratiche

This dissertation aims to examine the field of film festival subtitling by means of the analysis of two subtitling experiences. These experiences will be approached both on a methodological and on a practical level in order to analyse how subtitlers put theory into practice. This approach will also help underline the existing differences in work methodology as far as different work experiences are concerned. The subtitling experiences examined in this dissertation are part of my internships as a subtitler in two Italian film festivals, namely “Umbria Film Festival” and “900 Fest”. In this dissertation, I chose to focus on the subtitling of two of the audiovisual products I translated. These products are a German documentary titled Befreier und Befreite and a Danish fiction film titled Stille Hjerte. This dissertation is divided into five chapters. Chapter 1 describes audiovisual translation at its most theoretical level, focusing on subtitling criteria and strategies. Chapter 2 examines the concept of film translation, focusing on the distinctive features of documentary translation as a specific genre. This chapter also presents the concept of film festival and provides information concerning the translation policies of festivals. Chapter 3 presents the festivals I worked for and details my internship experiences. Chapter 4 focuses on the German documentary and proposes a number of solutions to its main translation problems. Chapter 5 focuses on the Danish film and offers solutions to its translation problems. At the end of the dissertation, I will provide some comments on my internship experiences as well as on the practice of film festival subtitling.

Polizeigeschosse und ihre Deformation

In den Jahren 2001 bis 2007 ist bei den Polizeien der deutschen Bundesländer und bei den Polizeikorps der Schweiz die so genannte Polizeimunition eingeführt worden. Von dieser mit einem deformierenden Geschoss ausgerüsteten Munition verspricht man sich eine größere Wirksamkeit und wegen der begrenzten Durchschlagsleistung eine geringere Gefährdung unbeteiligter Personen. Bei geringerer Auftreffenergie deformiert sich jedoch das Geschoss weniger, die Wirksamkeit wird kleiner und die Eindringtiefe größer. In der hier vorgestellten Arbeit wurde die Abhängigkeit der Deformation und der Eindringtiefe in ballistische Seife von der Auftreffenergie für alle 4 gegenwärtig vorhandenen Polizeigeschosse untersucht. Bereits bei Schussdistanzen von 25–30 m ist mit einer verminderten Wirksamkeit zu rechnen. Bei einer viel gebrauchten Waffe kann zudem die Mündungsenergie so stark reduziert sein, dass sich bereits bei kurzen Schussdistanzen die Geschosse nicht mehr erwartungsgemäß deformieren.

Biologically based strategies to augment rotator cuff tears

Lesions of the rotator cuff (RC) are among the most frequent tendon injuries. In spite of the developments in both open and arthroscopic surgery, RC repair still very often fails. In order to reduce the failure rate after surgery, several experimental in vitro and in vivo therapy methods have been developed for biological improvement of the reinsertion. This article provides an overview of the current evidence for augmentation of RC reconstruction with growth factors. Furthermore, potential future therapeutic approaches are discussed. We performed a comprehensive search of the PubMed database using various combinations of the keywords "tendon," "rotator cuff," "augmentation," "growth factor," "platelet-rich fibrin," and "platelet-rich plasma" for publications up to 2011. Given the linguistic capabilities of the research team, we considered publications in English, German, French, and Spanish. We excluded literature reviews, case reports, and letters to the editor.

Bipolar disorder risk alleles in children with ADHD

Bipolar disorder (BD) and attention deficit/hyperactivity disorder (ADHD) may share common genetic risk factors as indicated by the high co-morbidity of BD and ADHD, their phenotypic overlap especially in pediatric populations, the high heritability of both disorders, and the co-occurrence in families. We therefore examined whether known polygenic BD risk alleles are associated with ADHD. We chose the eight best SNPs of the recent genome-wide association study (GWAS) of BD patients of German ancestry and the nine SNPs from international GWAS meeting a 'genome-wide significance' level of α = 5 × 10(-8). A GWAS was performed in 495 ADHD children and 1,300 population-based controls using HumanHap550v3 and Human660 W-Quadv1 BeadArrays. We found no significant association of childhood ADHD with single BD risk alleles surviving adjustment for multiple testing. Yet, risk alleles for BD and ADHD were directionally consistent at eight of nine loci with the strongest support for three SNPs in or near NCAN, BRE, and LMAN2L. The polygene analysis for the BP risk alleles at all 14 loci indicated a higher probability of being a BD risk allele carrier in the ADHD cases as compared to the controls. At a moderate power to detect association with ADHD, if true effects were close to estimates from GWAS for BD, our results suggest that the possible contribution of BD risk variants to childhood ADHD risk is considerably lower than for BD. Yet, our findings should encourage researchers to search for common genetic risk factors in BD and childhood ADHD in future studies.

Municipal Self-Government in the Ukrainian Lands: 14th-16th Centuries

This project considered the development of municipal self-government (particularly the Magdeburg-law type) in Ukraine through the late Middle Ages in the context of central and eastern European history, using a comparative analysis of different forms of self-government. The Magdeburg Law was brought to the lands of old Rus by German colonists in the period of the Galician-Volhynian State (in the late 13th-early 14th centuries). Municipal self-government based on this law in Ukraine was now however an external artificial phenomenon, but rather an intrinsic need that emerged during the historical development of the society. The Magdeburg Law reached Ukraine through Poland and acquired certain features which were different from the form used in German towns, and Ukrainian towns further adapted the Magdeburg model to their own circumstances. It was "purest" in the western part of the region, while further to the east Magdeburg-Law-type municipal government appeared later, was further removed from its original form, and had a weaker influence on the historical development of the towns. The Magdeburg Law came to be a legalisation of a historically determined process of the emergence of an urban estate.

Language, Thought, Relativism, Nationalism: An Interdisciplinary Study

Ms. Neumer and her team began their project with a critical analysis of the various theories of the relationship between language and thought. Their aim was to develop a theoretical position concerning the issue of universalism versus relativism. This issue is closely bound up with one of the main questions of the history of East and Central Europe, namely, the question of the nation, and the possibility of mutual understanding between national cultures. The team attempted to avoid falling into an all-too-common trap, that of allowing a political perspective to obscure the central theoretical issues. In a project whose outcome totalled over 1000 pages of manuscript in German, English and Hungarian, they touched on cognitive psychological, linguistic, semiotic, socio-semiotic, and other such themes. Their experience has convinced them of the fruitful heuristic possibilities of the interaction of scientific and philosophical approaches in this area of research. A preliminary analysis of the history of philosophy and inquiries into conceptual fields revealed that, in order to reach strong relativist conclusions concerning the unity of thought and language, it is required to take as a point of departure the widest possible sense of these concepts. But in fact, such an option ends up refuting itself: pursuing the premises to their final conclusion one arrives at the restriction of relativism. The team outlined a theory of the understanding of the Other which, borrowing from analytical as well as continental-hermeneutic trends, does not underestimate, on the one hand, the difficulties of understanding between various forms of life, cultures, and languages, but, on the other hand, can provide an alternative solution to the theory of incommensurabiltiy. Within the boundary of this problematic the team studied the problems of translatability, the acquisition of the mother and foreign languages, and natural or cultural determinacy of kind terms. The team regards its most original contribution to be the association of the problem of relativism-universalism and the language-thought relation with contemporary investigations into the question of orality, literacy, and secondary orality. Their conclusion was that, although certain connections can be revealed both between forms of communication and the thesis of the unity of language and thought, and between periods in the history of communication and the predominance of relativistic or universalistic tendencies, forms of communication do not unequivocally determine the answers to these questions.

The bovine aristaless-like homeobox 4 (ALX4) as a candidate gene for syndactyly

The ALX4 (aristaless-like homeobox 4) gene encodes a paired-type homeodomain transcriptional activator and plays a major role in anterior-posterior pattern formation during limb development. Here, the cloning, genomic structure and expression of the bovine ortholog of the ALX4 gene are reported. The bovine ALX4 gene consists of four exons and is located on BTA15q28-->q29 in a region syntenic to HSA11p11.2. The transcribed ALX4 mRNA encodes a 397-amino-acid protein showing a paired-type homeodomain and a C-terminal stretch of amino acids known as the OAR- or aristaless domain. The predicted protein shares 92.5% identity to human and mouse ALX4 proteins and all three species share almost complete identity in the conserved domains. ALX4 expression was detected by reverse transcriptase polymerase chain reaction in bovine fetal limb bones. The ALX4 gene was evaluated as a candidate gene for bovine syndactyly which has been mapped on the telomeric region of cattle chromosome 15. Sequencing of the four exons with flanking sequences of the bovine ALX4 gene from a panel of 14 affected animals belonging to German Holstein, German Fleckvieh and crossbreds, and 27 unaffected individuals from German Holstein revealed five silent SNPs within the coding region out of eleven SNPs in total. Four SNPs were polymorphic in the affected animals, but in comparison to the genotyped unaffected individuals the genotype distribution showed no evidence for an association to the phenotype. Therefore our data indicate that the ALX4 gene can probably be excluded as candidate gene for bovine syndactyly in the examined animals.

Keratin variants associate with progression of fibrosis during chronic hepatitis C infection

Keratins 8 and 18 (K8/K18) protect the liver from various forms of injury. Studies of liver explants from a large cohort of U.S. patients showed that K8/K18 mutations confer a risk to developing end-stage liver diseases, though which diseases are preferentially involved is unknown. We tested the hypothesis that K8/K18 variants are associated with chronic hepatitis C (CHC) and that their presence correlates with progression of fibrosis. Genomic DNA was isolated from peripheral blood of a well-characterized German cohort of 329 patients with CHC infection. Exonic regions were PCR-amplified and analyzed using denaturing high-performance liquid chromatography and DNA sequencing. Our findings showed: (1) amino acid altering keratin heterozygous variants in 24 of 329 CHC patients (7.3%) and non-coding heterozygous variants in 26 patients (7.8%), and (2) 3 new exonic K8 variants (T26R/G55A/A359T); 6 novel non-coding variants and one K18 coding variant (K18 S230T; 2 patients). The most common variants were K8 R341H (10 patients), K8 G62C (6 patients) and K8 I63V (4 patients). A novel and exclusive association of an intronic KRT8 IVS7+10delC deletion in all 10 patients with K8 R341H was observed. Notably, there was a significant association of exonic, but not of intronic K8 variants with increased fibrosis. In conclusion, previously described and novel K8 variants are present in a German population and collectively associate with progression of fibrosis in CHC infection. The unique 100% segregation of the most common K8 variant, R341H, with an intronic deletion suggests that one of these two genetic changes might lead to the other.

Congenital syndactyly in cattle: four novel mutations in the low density lipoprotein receptor-related protein 4 gene (LRP4)

BACKGROUND: Isolated syndactyly in cattle, also known as mulefoot, is inherited as an autosomal recessive trait with variable penetrance in different cattle breeds. Recently, two independent mutations in the bovine LRP4 gene have been reported as the primary cause of syndactyly in the Holstein and Angus cattle breeds. RESULTS: We confirmed the previously described LRP4 exon 33 two nucleotide substitution in most of the affected Holstein calves and revealed additional evidence for allelic heterogeneity by the identification of four new LRP4 non-synonymous point mutations co-segregating in Holstein, German Simmental and Simmental-Charolais families. CONCLUSION: We confirmed a significant role of LRP4 mutations in the pathogenesis of congenital syndactyly in cattle. The newly detected missense mutations in the LRP4 gene represent independent mutations affecting different conserved protein domains. However, the four newly described LRP4 mutations do still not explain all analyzed cases of syndactyly.

Family satisfaction in the intensive care unit: cross-cultural adaptation of a questionnaire

PURPOSE: Family needs and expectations are often unmet in the intensive care unit (ICU), leading to dissatisfaction. This study assesses cross-cultural adaptability of an instrument evaluating family satisfaction in the ICU. MATERIALS AND METHODS: A Canadian instrument on family satisfaction was adapted for German language and central European culture and then validated for feasibility, validity, internal consistency, reliability, and sensitivity. RESULTS: Content validity of a preliminary translated version was assessed by staff, patients, and next of kin. After adaptation, content and comprehensibility were considered good. The adapted translation was then distributed to 160 family members. The return rate was 71.8%, and 94.4% of questions in returned forms were clearly answered. In comparison with a Visual Analogue Scale, construct validity was good for overall satisfaction with care (Spearman rho = 0.60) and overall satisfaction with decision making (rho = 0.65). Cronbach alpha was .95 for satisfaction with care and .87 for decision-making. Only minor differences on repeated measurements were found for interrater and intrarater reliability. There was no floor or ceiling effect. CONCLUSIONS: A cross-cultural adaptation of a questionnaire on family satisfaction in the ICU can be feasible, valid, internally consistent, reliable, and sensitive.

Türkische Übersetzung und erste psychometrische Überprüfung der deutschsprachigen FAMOS (Fragebogen zur Analyse Motivationaler Schemata) und INK (Inkongruenzfragebogen)

Theoretischer Hintergrund: Standardisierte psychologische Messinstrumente in der Psychotherapie für Personen mit Migrationshintergrund fehlen weitgehend. Fragestellungen: Die türkischsprachigen Übersetzungen des Fragebogens zur Analyse Motivationaler Schemata (FAMOS) und des Inkongruenzfragebogens (INK) wurden in die türkische Sprache übersetzt und psychometrisch überprüft. Methode: Insgesamt füllten 73 türkischsprachige Patienten und 230 gesunde türkischsprachige Personen mit Migrationshintergrund in der Schweiz FAMOS und INK aus. Ergebnisse: Die Skalen von FAMOS und INK zeigen gute Reliabilität und Validität. Patienten weisen stärker ausgeprägte Vermeidungsziele und Inkongruenzwerte als gesunde Personen auf. Schlussfolgerungen: Die türkischen Versionen von FAMOS und INK eignen sich sowohl für die klinisch-psychologische Forschung als auch für die Praxis.

Validation of the LittlEARS((R)) Auditory Questionnaire in children with normal hearing

OBJECTIVES: With more children receiving cochlear implants during infancy, there is a need for validated assessments of pre-verbal and early verbal auditory skills. The LittlEARS Auditory Questionnaire is presented here as the first module of the LittlEARS test battery. The LittlEARS Auditory Questionnaire was developed and piloted to assess the auditory behaviour of normal hearing children and hearing impaired children who receive a cochlear implant or hearing aid prior to 24 months of age. This paper presents results from two studies: one validating the LittlEARS Auditory Questionnaire on children with normal hearing who are German speaking and a second validating the norm curves found after adaptation and administration of the questionnaire to children with normal hearing in 15 different languages. METHODS: Scores from a group of 218 German and Austrian children with normal hearing between 5 days and 24 months of age were used to create a norm curve. The questionnaire was adapted from the German original into English and then 15 other languages to date. Regression curves were found based on parental responses from 3309 normal hearing infants and toddlers. Curves for each language were compared to the original German validation curve. RESULTS: The results of the first study were a norm curve which reflects the age-dependence of auditory behaviour, reliability and homogeneity as a measure of auditory behaviour, and calculations of expected and critical values as a function of age. Results of the second study show that the regression curves found for all the adapted languages are essentially equal to the German norm curve, as no statistically significant differences were found. CONCLUSIONS: The LittlEARS Auditory Questionnaire is a valid, language-independent tool for assessing the early auditory behaviour of infants and toddlers with normal hearing. The results of this study suggest that the LittlEARS Auditory Questionnaire could also be very useful for documenting children's progress with their current amplification, providing evidence of the need for implantation, or highlighting the need for follow-up in other developmental areas.