PERCEPÇÃO DE AUTO-ESTIMA E QUALIDADE DE VIDA DO JOVEM-ADULTO SURDO UNIVERSITÁRIO

O presente trabalho tem como tema central a opinião do surdo universitário sobre sua auto- estima e qualidade vida. Os objetivos foram conhecer o joven-adulto surdo universitário, segundo sua opinião, buscando especificamente identificar os fatores que contribuíram para o seu desenvolvimento psicológico e sua auto-estima; e identificar as características da qualidade de vida, considerando os aspectos físico, psicológico, relações sociais e meio ambiente. Participaram desta pesquisa 3 jovens-adultos surdos, universitários. O método utilizado foi o descritivo qualitativo, usando-se como fonte de coleta de dados a entrevista livre e o WHOQOL-bref. O método qualitativo na área da saúde visa investigar o significado que os fenômenos sentimentos, idéias, vivências, manifestações, dentre outros, tem para as pessoas e que dão molde às suas vidas incluindo os cuidados com a saúde. Percebemos que ao atingirem a fase adulta, os sujeitos pesquisados conseguem tomar decisões e escolher seus caminhos com maior liberdade em função das experiências e condições que lhes foram apresentadas. Verificamos que as situações vividas no ambiente escolar e o aprendizado da língua de sinais contribuíram para sua constituição como sujeito não limitado à condição da surdez. Foi possível identificar que possuem expectativas profissionais futuras e expressaram suas dificuldades, desejos, frustrações diante do mercado de trabalho, relações sociais e familiares como qualquer outro individuo, encontrando recursos internos para o enfrentamento das circunstâncias cotidianas. Os resultados da pesquisa também permitiram observar que os surdos reconhecem o grau de satisfação que têm com a vida, seu estado de saúde e cuidados com seu bem-estar físico, psicológico e social. Concluímos que ao recontar sua história de vida os surdos têm a possibilidade de se reconhecer como sujeitos e a oportunidade de dar continuidade às próprias vivências que contribuíram para seu bem-estar

PERCEPÇÃO DE AUTO-ESTIMA E QUALIDADE DE VIDA DO JOVEM-ADULTO SURDO UNIVERSITÁRIO

O presente trabalho tem como tema central a opinião do surdo universitário sobre sua auto- estima e qualidade vida. Os objetivos foram conhecer o joven-adulto surdo universitário, segundo sua opinião, buscando especificamente identificar os fatores que contribuíram para o seu desenvolvimento psicológico e sua auto-estima; e identificar as características da qualidade de vida, considerando os aspectos físico, psicológico, relações sociais e meio ambiente. Participaram desta pesquisa 3 jovens-adultos surdos, universitários. O método utilizado foi o descritivo qualitativo, usando-se como fonte de coleta de dados a entrevista livre e o WHOQOL-bref. O método qualitativo na área da saúde visa investigar o significado que os fenômenos sentimentos, idéias, vivências, manifestações, dentre outros, tem para as pessoas e que dão molde às suas vidas incluindo os cuidados com a saúde. Percebemos que ao atingirem a fase adulta, os sujeitos pesquisados conseguem tomar decisões e escolher seus caminhos com maior liberdade em função das experiências e condições que lhes foram apresentadas. Verificamos que as situações vividas no ambiente escolar e o aprendizado da língua de sinais contribuíram para sua constituição como sujeito não limitado à condição da surdez. Foi possível identificar que possuem expectativas profissionais futuras e expressaram suas dificuldades, desejos, frustrações diante do mercado de trabalho, relações sociais e familiares como qualquer outro individuo, encontrando recursos internos para o enfrentamento das circunstâncias cotidianas. Os resultados da pesquisa também permitiram observar que os surdos reconhecem o grau de satisfação que têm com a vida, seu estado de saúde e cuidados com seu bem-estar físico, psicológico e social. Concluímos que ao recontar sua história de vida os surdos têm a possibilidade de se reconhecer como sujeitos e a oportunidade de dar continuidade às próprias vivências que contribuíram para seu bem-estar

Essential role of POU–domain factor Brn-3c in auditory and vestibular hair cell development

The Brn-3 subfamily of POU–domain transcription factor genes consists of three highly homologous members—Brn-3a, Brn-3b, and Brn-3c—that are expressed in sensory neurons and in a small number of brainstem nuclei. This paper describes the role of Brn-3c in auditory and vestibular system development. In the inner ear, the Brn-3c protein is found only in auditory and vestibular hair cells, and the Brn-3a and Brn-3b proteins are found only in subsets of spiral and vestibular ganglion neurons. Mice carrying a targeted deletion of the Brn-3c gene are deaf and have impaired balance. These defects reflect a complete loss of auditory and vestibular hair cells during the late embryonic and early postnatal period and a secondary loss of spiral and vestibular ganglion neurons. Together with earlier work demonstrating a loss of trigeminal ganglion neurons and retinal ganglion cells in mice carrying targeted disruptions in the Brn-3a and Brn-3b genes, respectively, the Brn-3c phenotype reported here demonstrates that each of the Brn-3 genes plays distinctive roles in the somatosensory, visual, and auditory/vestibular systems.

Transient “deafness” accompanies auditory development during metamorphosis from tadpole to frog

During metamorphosis, ranid frogs shift from a purely aquatic to a partly terrestrial lifestyle. The central auditory system undergoes functional and neuroanatomical reorganization in parallel with the development of new sound conduction pathways adapted for the detection of airborne sounds. Neural responses to sounds can be recorded from the auditory midbrain of tadpoles shortly after hatching, with higher rates of synchronous neural activity and lower sharpness of tuning than observed in postmetamorphic animals. Shortly before the onset of metamorphic climax, there is a brief “deaf” period during which no auditory activity can be evoked from the midbrain, and a loss of connectivity is observed between medullary and midbrain auditory nuclei. During the final stages of metamorphic development, auditory function and neural connectivity are restored. The acoustic communication system of the adult frog emerges from these periods of anatomical and physiological plasticity during metamorphosis.

Mouse Deformed epidermal autoregulatory factor 1 recruits a LIM domain factor, LMO-4, and CLIM coregulators

Nuclear LIM domains interact with a family of coregulators referred to as Clim/Ldb/Nli. Although one family member, Clim-2/Ldb-1/Nli, is highly expressed in epidermal keratinocytes, no nuclear LIM domain factor is known to be expressed in epidermis. Therefore, we used the conserved LIM-interaction domain of Clim coregulators to screen for LIM domain factors in adult and embryonic mouse skin expression libraries and isolated a factor that is highly homologous to the previously described LIM-only proteins LMO-1, -2, and -3. This factor, referred to as LMO-4, is expressed in overlapping manner with Clim-2 in epidermis and in several other regions, including epithelial cells of the gastrointestinal, respiratory and genitourinary tracts, developing cartilage, pituitary gland, and discrete regions of the central and peripheral nervous system. Like LMO-2, LMO-4 interacts strongly with Clim factors via its LIM domain. Because LMO/Clim complexes are thought to regulate gene expression by associating with DNA-binding proteins, we used LMO-4 as a bait to screen for such DNA-binding proteins in epidermis and isolated the mouse homologue of Drosophila Deformed epidermal autoregulatory factor 1 (DEAF-1), a DNA-binding protein that interacts with regulatory sequences first described in the Deformed epidermal autoregulatory element. The interaction between LMO-4 and mouse DEAF-1 maps to a proline-rich C-terminal domain of mouse DEAF-1, distinct from the helix–loop–helix and GATA domains previously shown to interact with LMOs, thus defining an additional LIM-interacting domain.

Targeted disruption of the Kcnq1 gene produces a mouse model of Jervell and Lange– Nielsen Syndrome

KCNQ1 encodes KCNQ1, which belongs to a family of voltage-dependent K+ ion channel proteins. KCNQ1 associates with a regulatory subunit, KCNE1, to produce the cardiac repolarizing current, IKs. Loss-of-function mutations in the human KCNQ1 gene have been linked to Jervell and Lange–Nielsen Syndrome (JLNS), a disorder characterized by profound bilateral deafness and a cardiac phenotype. To generate a mouse model for JLNS, we created a line of transgenic mice that have a targeted disruption in the Kcnq1 gene. Behavioral analysis revealed that the Kcnq1−/− mice are deaf and exhibit a shaker/waltzer phenotype. Histological analysis of the inner ear structures of Kcnq1−/− mice revealed gross morphological anomalies because of the drastic reduction in the volume of endolymph. ECGs recorded from Kcnq1−/− mice demonstrated abnormal T- and P-wave morphologies and prolongation of the QT and JT intervals when measured in vivo, but not in isolated hearts. These changes are indicative of cardiac repolarization defects that appear to be induced by extracardiac signals. Together, these data suggest that Kcnq1−/− mice are a potentially valuable animal model of JLNS.

Processing of speech signals for physical and sensory disabilities.

Assistive technology involving voice communication is used primarily by people who are deaf, hard of hearing, or who have speech and/or language disabilities. It is also used to a lesser extent by people with visual or motor disabilities. A very wide range of devices has been developed for people with hearing loss. These devices can be categorized not only by the modality of stimulation [i.e., auditory, visual, tactile, or direct electrical stimulation of the auditory nerve (auditory-neural)] but also in terms of the degree of speech processing that is used. At least four such categories can be distinguished: assistive devices (a) that are not designed specifically for speech, (b) that take the average characteristics of speech into account, (c) that process articulatory or phonetic characteristics of speech, and (d) that embody some degree of automatic speech recognition. Assistive devices for people with speech and/or language disabilities typically involve some form of speech synthesis or symbol generation for severe forms of language disability. Speech synthesis is also used in text-to-speech systems for sightless persons. Other applications of assistive technology involving voice communication include voice control of wheelchairs and other devices for people with mobility disabilities.

Age-related functional and structural retinal modifications in the Igf1−/− null mouse

Background. Mutations in the gene encoding human insulin-like growth factor-I (IGF-I) cause syndromic neurosensorial deafness. To understand the precise role of IGF-I in retinal physiology, we have studied the morphology and electrophysiology of the retina of the Igf1−/− mice in comparison with that of the Igf1+/− and Igf1+/+ animals during aging. Methods. Serological concentrations of IGF-I, glycemia and body weight were determined in Igf1+/+, Igf1+/− and Igf1−/− mice at different times up to 360 days of age. We have analyzed hearing by recording the auditory brainstem responses (ABR), the retinal function by electroretinographic (ERG) responses and the retinal morphology by immunohistochemical labeling on retinal preparations at different ages. Results. IGF-I levels are gradually reduced with aging in the mouse. Deaf Igf1−/− mice had an almost flat scotopic ERG response and a photopic ERG response of very small amplitude at postnatal age 360 days (P360). At the same age, Igf1+/− mice still showed both scotopic and photopic ERG responses, but a significant decrease in the ERG wave amplitudes was observed when compared with those of Igf1+/+ mice. Immunohistochemical analysis showed that P360 Igf1−/− mice suffered important structural modifications in the first synapse of the retinal pathway, that affected mainly the postsynaptic processes from horizontal and bipolar cells. A decrease in bassoon and synaptophysin staining in both rod and cone synaptic terminals suggested a reduced photoreceptor output to the inner retina. Retinal morphology of the P360 Igf1+/− mice showed only small alterations in the horizontal and bipolar cell processes, when compared with Igf1+/+ mice of matched age. Conclusions. In the mouse, IGF-I deficit causes an age-related visual loss, besides a congenital deafness. The present results support the use of the Igf1−/− mouse as a new model for the study of human syndromic deaf-blindness.

Educación bilingüe del alumnado sordo: pilares para un cambio estratégico

Pese a los progresos logrados en la protección de los derechos fundamentales de salud y educación de las personas sordas usuarias de las lenguas de signos, a menudo se sigue negando a niños sordos su derecho a aprender y usar las lenguas de signos en su educación y en entornos físicos y psicosociales accesibles de conformidad con la Convención de los Derechos de las Personas con Discapacidad (CDPD) y con las recientes leyes 27/2007 y 17/2007. El objetivo principal de este estudio fue obtener información sobre los factores estratégicos que favorecen una escuela saludable e inclusiva, mediante programas de educación bilingüe sostenibles y de calidad para escolares sordos en España. La metodología utilizada consistió en un estudio descriptivo con componentes de investigación-acción participativa y un enfoque de análisis estratégico. Como resultados, cabe destacar que las principales macrotendencias que, en el ámbito internacional, han promovido el cambio hacia prácticas bilingües son dos: en primer lugar, los cambios sociales y políticos que tienden a una creciente aceptación de la diversidad y los temas relacionados con las personas sordas; y en segundo lugar, una tendencia a un activismo, una autoconciencia y un apoderamiento crecientes por parte de las personas sordas. Como contrapartida, las que lo han obstaculizado son, por un lado, la visión de la sordera como una condición médica, que puede solucionarse mediante la tecnología; y por otro lado, el fonocentrismo, unido a una cierta resistencia social a lo desconocido. Aunque en España algunas de las escuelas que han iniciado el cambio cumplen las recomendaciones de la CDPD, la mayoría están todavía en una fase preliminar de formulación o puesta en práctica de este nuevo modelo y distan mucho de encontrarse distribuidas de manera igualitaria en las diferentes comunidades autónomas. Como conclusión podemos decir que conseguir una educación más saludable e inclusiva para los escolares sordos implica poner en marcha una estrategia de actuación planificada en la que participen activamente todos los sectores y organismos relevantes implicados y, en particular, las comunidades sordas a través de las organizaciones que las representan. Sin un cambio radical de perspectiva, la salud y la educación no serán accesibles a todos y las desigualdades sociales se verán acentuadas.

Why the EU must reengage with Turkey. EPC Commentary, 29 September 2014

Democratic values and basic rights in Turkey are hanging by a thread. Over the past eighteen months the rule of law, civil liberties and freedoms have been eroded which has left many Turks anxious over the direction in which their country is heading. With Turkey’s accession negotiations de facto frozen, the EU finds itself with little leverage over Ankara. Calls of concern have fallen on deaf ears as Turkey’s leadership has become increasingly belligerent, with its EU related narrative overflowing with resentment. Because Turkey’s accession negotiations are irreversibly intertwined with Turkey-EU cooperation in other areas, this has had a negative impact on the broader relationship between both sides. Recent examples include the issue of foreign fighters traveling from Europe to Syria via Turkey. Each side has accused the other of not doing enough to stem the flow. Likewise, following the decision of Russian President, Vladimir Putin, to ban the import of agricultural goods from countries that have placed sanctions on Moscow, the EU asked Turkey to demonstrate solidarity, as a “candidate country”, and not to increase exports of agricultural products to Russia. Turkey rejected this request and is reportedly working on strengthening trade ties with Moscow. Turkey remains an important partner in a number of key areas including trade, energy, foreign and security policy and migration. At a time when the EU faces crises in both its Eastern and Southern neighbourhoods, a reliable and predictable Turkey, with which it can cooperate in the Black Sea and Middle East neighbourhoods is crucial. Hence the vision and plans of the EU’s new leadership, in particular new Foreign Policy Chief, Federica Mogherini, and Commissioner for European Neighbourhood Policy and Enlargement Negotiations, Johannes Hahn, how to shape relations with Ankara is particularly significant. The Union’s current policy is counterproductive and is further eroding trust and cooperation rather than enhancing it. It needs to be turned around.

The Lyon phonetic manual,

This printing includes an introductory notice with the Directors and Officers of the Association listed.

Report.

Bound with report for 1871-72 is Report on institutions for the deaf and dumb and the blind in Europe and in the United States of America ... By Dr. Ryerson. Toronto, 1868.

Eleventh census of the United States, 1890.

Originally published: Washington : G.P.O., 1892-1897.

Report.

1863- MN Institution for the Education of the Deaf and Dumb; 18 -1884, MN Institution for the Education of the Deaf and Dumb, and the Blind; 1886- MN Institute for Defectives.

Cours élémentaire d'éducation des sourds et muets /

Contiene con portada propia y fechada en 1778 "Dissertation sur la Parole"