847 resultados para DIN
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The finite element method is of great importance for the development and analysis of a new product being designed or already on the market, and that requires some specific request or special application. The tower crane, being an essential equipment for modern construction to increase productivity and safety on construction sites, is required for many types of special applications day after day, in many kinds of work. Paying attention to this growing need for handling special projects for the tower crane, faced with the importance and necessity of development and improvement of knowledge in more accurate and practical calculation methods such as the finite element method , for greater agility and precision in the response to a new project. The tower crane is defined by the maximum load moment that it can act with a certain amount of load. The tower crane which will be analyzed in this work , for example, is a tower crane with a resulting capacity of 85 Metric Tons which are considered basic dimensions data of a fisical tower crane of a crane company Liebherr in Guaratinguetá . Thus, the project analysis will begin with the threedimensional representation of the crane lines with AutoCAD software , conversion of this model to the format accepted ANSYS Workbench and completion of 3D modeling of structural components in Design module ANSYS software. After structural modeling is completed, the simulation is performed in static simulation of ANSYS Workbench software mode. The standards will be adopted to DIN (Deutsches Institut für Normung) and EN 14439 (Europäische Normung 14439) and some NR 's related to specific security class of tower cranes, which will be referred throughout the work
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Pós-graduação em Física - IGCE
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Receiving coastal waters and estuaries are among the most nutrient-enriched environments on earth, and one of the symptoms of the resulting eutrophication is the proliferation of opportunistic, fast-growing marine seaweeds. Here, we used a widespread macroalga often involved in blooms, Ulva spp., to investigate how supply of nitrogen (N) and phosphorus (P), the two main potential growth-limiting nutrients, influence macroalgal growth in temperate and tropical coastal waters ranging from low- to high-nutrient supplies. We carried out N and P enrichment field experiments on Ulva spp. in seven coastal systems, with one of these systems represented by three different subestuaries, for a total of nine sites. We showed that rate of growth of Ulva spp. was directly correlated to annual dissolved inorganic nitrogen (DIN) concentrations, where growth increased with increasing DIN concentration. Internal N pools of macroalgal fronds were also linked to increased DIN supply, and algal growth rates were tightly coupled to these internal N pools. The increases in DIN appeared to be related to greater inputs of wastewater to these coastal waters as indicated by high delta 15N signatures of the algae as DIN increased. N and P enrichment experiments showed that rate of macroalgal growth was controlled by supply of DIN where ambient DIN concentrations were low, and by P where DIN concentrations were higher, regardless of latitude or geographic setting. These results suggest that understanding the basis for macroalgal blooms, and management of these harmful phenomena, will require information as to nutrient sources, and actions to reduce supply of N and P in coastal waters concerned.
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Southern Brazil is considered an area of low Hepatitis B endemicity, but some areas of higher endemicity have been described in the Southwest of Parana and Santa Catarina states. The aim of this study was to evaluate viral genotypes circulating throughout Parana state. PCR amplification and partial sequencing of the S gene was carried out in 228 samples from HBsAg positive candidate blood donors. Samples have been collected in seven different counties (Cascavel, Curitiba, Foz do Iguacu, Francisco Beltrao, Matinga Londrina and Paranagua). The most common HBV genotype in Parana state was D (82.9%; 189/228), followed by A (14.1%; 32/228). Genotypes F (1.3%; 3/228), C (1.3%; 3/228) and H (0.4%; 1/228) were also found. Distribution of genotypes was different in the studied counties, but genotype D was the most frequent in all of them. In Francisco Beltrao, all studied samples belonged to genotype D. The high prevalence of HBV genotype Din South of Brazil is explained by the intense migration of settlers from Europeans countries. Subgenotypes A1 and A2 were identified circulating in all cities where HBV/A was found. As observed in other areas of Brazil, HBV/A1 is more frequent than the HBV/A2 in Parana state and its presence was significantly larger in black and mulatto individuals. Genotype C was found only in individuals with Asian ancestry from Londrina and Maringa. Most HBV/F sequences identified in this study were classified as subgenotype F2a that was previously described in Brazil. The sole case of subgenotype F4 was from Foz do Iguacu city, near to Northern Argentina, where F4 is highly prevalent. The single genotype H sample was from Curitiba. This is the first case of this genotype described in Brazil. Further studies should be carried out to determine if more genotype H samples can be found in other populations from Brazil. (C) 2012 Elsevier B.V. All rights reserved.
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Os objetivos do estudo foram descrever a disposição sobre o Processo de Enfermagem (PE) e a percepção de poder clínico dos profissionais de enfermagem; analisar associações entre atitudes relacionadas ao PE e variáveis selecionadas. Participaram 1.605 auxiliares de enfermagem e enfermeiros (86,9% mulheres, idade média 44,12 anos; DP=9,55). O escore médio no instrumento Posições sobre o Processo de Enfermagem (PPE) foi 112,37 (DP=22,28) e no Power as Knowing Participation in Change Tool - versão brasileira (PKPCT) foi 281,12 (DP= 38,72). Os escores nos instrumentos foram mais altos para enfermeiros quando comparados aos auxiliares. Houve correlação positiva moderada entre escores do PPE e PKPCT. Para os auxiliares houve associação entre os escores no PPE, sexo e pós-graduação; e entre percepção de poder e sexo. Para os enfermeiros houve associação entre PKPCT e cargo de chefia. Mais estudos devem ser desenvolvidos com vistas a identificar variáveis potencialmente associadas ao uso do Processo de Enfermagem na prática clínica.
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Abstract Background Regardless the regulatory function of microRNAs (miRNA), their differential expression pattern has been used to define miRNA signatures and to disclose disease biomarkers. To address the question of whether patients presenting the different types of diabetes mellitus could be distinguished on the basis of their miRNA and mRNA expression profiling, we obtained peripheral blood mononuclear cell (PBMC) RNAs from 7 type 1 (T1D), 7 type 2 (T2D), and 6 gestational diabetes (GDM) patients, which were hybridized to Agilent miRNA and mRNA microarrays. Data quantification and quality control were obtained using the Feature Extraction software, and data distribution was normalized using quantile function implemented in the Aroma light package. Differentially expressed miRNAs/mRNAs were identified using Rank products, comparing T1DxGDM, T2DxGDM and T1DxT2D. Hierarchical clustering was performed using the average linkage criterion with Pearson uncentered distance as metrics. Results The use of the same microarrays platform permitted the identification of sets of shared or specific miRNAs/mRNA interaction for each type of diabetes. Nine miRNAs (hsa-miR-126, hsa-miR-1307, hsa-miR-142-3p, hsa-miR-142-5p, hsa-miR-144, hsa-miR-199a-5p, hsa-miR-27a, hsa-miR-29b, and hsa-miR-342-3p) were shared among T1D, T2D and GDM, and additional specific miRNAs were identified for T1D (20 miRNAs), T2D (14) and GDM (19) patients. ROC curves allowed the identification of specific and relevant (greater AUC values) miRNAs for each type of diabetes, including: i) hsa-miR-1274a, hsa-miR-1274b and hsa-let-7f for T1D; ii) hsa-miR-222, hsa-miR-30e and hsa-miR-140-3p for T2D, and iii) hsa-miR-181a and hsa-miR-1268 for GDM. Many of these miRNAs targeted mRNAs associated with diabetes pathogenesis. Conclusions These results indicate that PBMC can be used as reporter cells to characterize the miRNA expression profiling disclosed by the different diabetes mellitus manifestations. Shared miRNAs may characterize diabetes as a metabolic and inflammatory disorder, whereas specific miRNAs may represent biological markers for each type of diabetes, deserving further attention.
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ÈS] Se analiza la formación de pautas espaciales en una ecuación unidimensional de reacción-difusión cuando el coeficiente de difusividad depende de la distribución espacial de una especie, que actúa como control, cuya dinámica es rápida en comparación con la de la variable principal
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[ES]La zona costera representa una estrecha franja de la superficie de nuestro planeta, caracterizada por un comportamiento dinámico extraordinariamente complejo. Esta zona es única por interactuar directamente en ella los medios terrestre, marino y atmosférico. Además, debido al enorme interés del ser humano por utilizar dicho medio, se encuentra sometido a grandes presiones que llevan a la aparición de numerosos conflictos de tipo socioeconómico y ambiental. Las Islas Canarias poseen una gran extensión de costa con diferentes grados de exposición a condiciones severas de la dinámica marina, en particular del oleaje. Ello conlleva frecuentes estados de alerta y situaciones de emergencia en algunas zonas de su litoral. En consecuencia, resultan fundamentales el planeamiento y gestión eficaz de las intervenciones por parte de las entidades responsables, así como la realización de estudios de riesgo y la implantación de sistemas de alerta, con el objetivo de minimizar los daños sobre infraestructuras y, especialmente, en términos de vidas humanas. El objetivo principal es examinar la probabilidad de ocurrencia de eventos de remonte, capaces de rebasar diferentes cotas de nivel o inundación del terreno, así como el nivel de riesgo asociado a la inundación de las diferentes áreas en las que se puede segmentar la zona de la playa. La metodología aplicada para estimar la frecuencia de ocurrencia de eventos de remonte de diferente intensidad incluye, en primer lugar, la propagación de las condiciones de oleaje desde los puntos de medida hacia la zona de interés, considerando el nivel de marea asociado, mediante un modelo de propagación de oleaje de tercera generación. Posteriormente, conocidas las condiciones de oleaje a pie de playa, se hace uso de diversas formulaciones empíricas sugeridas en la literatura especializada para evaluar el remonte. La evaluación del riesgo tiene en cuenta el producto entre los grados de las probabilidades de ocurrencia y el grado de consecuencia. Así, una vez estimada la probabilidad asociada a diferentes niveles de remonte, se asigna un grado de consecuencia empleando la metodología propuesta por Laboratorio Nacional de Ingeniería Civil de Lisboa, LNEC, (Neves et al., 2010, Santos et al., 2011, Silva et al., 2011, Reis et al., 2011, Neves et al., 2012 Rocha et al., 2013; Poseiro et al., 2013, y de estas se deriva el nivel de riesgo. Por último, las conclusiones del estudio quedan reflejadas en un mapa de riesgos asociados al remonte del oleaje en la zona de estudio.
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[ES] El estándar Functional Mockup Interface (FMI), es un estándar abierto e independiente de cualquier aplicación o herramienta que permite compartir modelos de sistemas dinámicos entre aplicaciones. En FMI, se define una interfaz común (API) que permite la distribución e interoperabilidad de simulaciones. Así, una simulación puede transformarse en un formato ejecutable para su distribución con una interfaz pública conocida. En este estándar, una simulación se empaqueta en un formato de fichero llamado Functional Mock-up Unit (FMU). La ejecución de una simulación compleja en la que intervienen muchas FMUs es una necesidad que puede ser inviable de realizar en un sólo ordenador por la cantidad de recursos que consume.
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[ES] La conferencia tratará sobre el laborioso proceso de la preparación de la solicitud, el nombramiento definitivo por parte de la UNESCO y las oportunidades que representa este reconocimiento internacional para el desarrollo de la Isla de EL Hierro. El gran potencial del patrimonio geológico de la Isla constituye un importante recurso para contribuir al desarrollo social y económico de sus habitantes además de ser un laboratorio vivo en el conocimiento de la dinámica volcánica en islas oceánicas.
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Máster Universitario en Eficiencia Energética (SIANI)
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[ES]Entre mediados del siglo VIII y mediados del siglo XII, el espacio comprendido entre el Sistema Central y el río Tajo en su parte extremeña ejerció como confín territorial de al- Andalus. A lo largo de todo este tiempo se sucedieron distintas fases en las que la frontera fluctuó según vinieran los aires cristianos del norte o islámicos del sur. Ello provocaría que estos territorios actuaran con relativa autonomía en muchos momentos de su historia andalusí y que se convirtieran en zonas donde confluían gentes de toda condición social y religiosa. En el presente trabajo tratamos de vislumbrar las dinámicas territoriales y sociales que se dieron en aquella región hasta finales del siglo XI, cuando se produjeron las conquistas cristianas de las ciudades islámicas más importantes de la frontera. [EN] The geographical area between the Spanish Central System and the part of the Tagus passing through Extremadura served as the boundary of the al-Andalus from the 8th to the 12th century. The boundary had different phases that fluctuated according to the influence exercised by the northern Christians or southern Muslims. This allowed these territories to have relative autonomy during its Andalusian history and turned them into zones where people from different social and religious background converged. The aim of this paper is to analyse the territorial and social dynamics of this area until the end of the 11th century, when the Christians conquered the most important Islamic towns of the borderland.
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[EN]The capacity of the ocean to sequester atmospheric carbon (CO2) depends to a large extent on the dynamics of biogenic carbon in the water column. However, most current global and regional estimates of carbon balances are solely based on particles collected with drifting and moored sediment traps. As a consequence, construction of ocean carbon budgets has long been guided by the simplification introduced by sediment traps, which give a 1D vision of the whole picture. In this thesis we have assessed a quantitative analysis of the flux magnitude and the mechanisms of transport of the whole particle spectrum (suspended, slowly-sinking and sinking particles).
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[ES]A pesar del crecimiento constante y el asentamiento del e-learning como alternativa a algunas formas de educación presencial, existen aún áreas de investigación que pueden suponer avances importantes, según el informe horizon de 2015, entre ellas destacamos el BYOD y la Flipped clasroom la cual la hemos implementado a través del uso de las redes sociales y otros elementos del ecosistema digital, entre los que destacamos el protagonismo de las tecnologías móviles. En nuestro trabajo analizamos la combinación de estrategias y de metodologías activas e inductivas que permiten el desarrollo de habilidades y competencias digitales en donde las redes mediadas en entornos de ubicuidad, pueden convertirse en parte de la transformación educativa, ya que suponen un espacio colaborativo además de poder optimizar la dinámica de clase en la universidad.