993 resultados para Correa, Carlos
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Nitric oxide (NO) is a free radical with participation in almost all physiologic host processes; however, in high concentrations it may damage the tissues. Its immunoregulatory action is present in the inflammation and in auto-immune mechanisms, being intensively studied in the medical area. Recently, some studies have also reported that NO could play a role as etiopathogenic factor of the periodontal disease, which shows inflammatory and multifactorial course. Due to beneficial or damage effects of NO, according to its concentrations, some studies have been focused in the evaluation of inhibitor of NO-Synthase (NOS) as therapeutic agents in inflammatory processes. In this context, the aim of this study was to report the role of NO and NOS inhibition in the periodontal disease modulation process. In conclusion, it could be suggested that NO seems to play an essential role in evolution of inflammatory periodontal disease, and that the NOS inhibition may be considered as a promising therapeutic in modulation of inflammatory process.
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The Family Health Strategy is a primary care public policy that is becoming a decisive step towards the transformation of the Brazilian healthcare model. This study evaluated the dental knowledge among individuals who attended a Family-Health Unit (FHU) in the city of São Carlos, SP, Brazil. Methods: The evaluation was based on a questionnaire with 20 questions about oral health, prevention and development of dental caries and periodontal disease. The questionnaire was given to 168 individuals, over 18 years of age and both sexes, to fill out under the supervision of a trained dentist. After data collection, the answers contained in the original questionnaires were entered into a database built using the program Excel® (Microsoft Corporation, USA) and a descriptive statistical analysis was done. Results: 66.67% of the subjects reported having received information about dental caries and periodontal disease before attending the FHU, and dentists were cited as the main source of such information (60.71%). With regard to dental caries, 70.24% of the individuals stated that they knew about the subject, but the majority of answers revealed incorrect explanation of it. The multifactorial etiology (bacteria/sugar/poor hygiene) was not mentioned. A low percentage of subjects (24.40%) claimed to know what periodontal disease is, and of these, the highest percentage of responses was related to gingivitis (26.83%) and gingival bleeding (12.20%). Out of all subjects, 80.36% affirmed that oral hygiene is important, and among them, the main reasons cited were the maintenance of oral health (29.63%), to avoid diseases (16.30%) and to preserve and prevent disease (14.81%). Conclusion: Responses from the questionnaires revealed deficient dental knowledge among the individuals. To improve the understanding about this issue, the information obtained through the questionnaire can be used to develop educational programs that will focus specifically on the major deficiencies found.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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This paper deals with characteristically anti-authoritarian aspects of Antônio Carlos de Brito’s work, alias Cacaso (1944-1987). It aims to provide evidence on his peculiar poetry writing exercise, which incorporates political and aesthetic tensions into its own language, rather than just refer to them. By anchoring in a poetics of everyday life and by being engaged in a dialogue with Brazilian literary tradition, Cacaso manages image, tone and emotion in order to instantly illuminate the impasses of his generation.
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Although vancomycin-resistant enterococci (VRE) are reported in Brazil since 1996, data on their impact over settings of different complexity are scarce. We performed a study aimed at identifying determinants ofVRE emergence and spread in a public hospital consortium (comprising 2 hospitals, with 318 and 57 beds) in inner Brazil. Molecular typing and case-control studies (addressing predictors of acquisition or clonality) were performed. Among 122 authocthonous isolates, 106 were Enterococcus faecium (22 clones), and 16, Enterococcus faecalis (5 clones). Incidence was greater in the small-sized hospital, and a previous admission to this hospital was associated with greater risk of VRE colonization or infection during admission to the larger one. Overall risk factors included comorbidities, procedures, and antimicrobials (piperacillin-tazobactam, cefepime, and imipenem). Risk factors varied among different hospitals, species, and clones. Our findings demonstrate that VRE can spread within low-complexity facilities and from these to larger hospitals. (C) 2015 Elsevier Inc. All rights reserved.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Antitrypanosomal acetylene fatty acid derivatives from the seeds of porcelia macrocarpa (annonaceae)
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)