A Metamorfose do Estudante: análise das relações entre o locus de controlo e a adaptação dos estudantes de primeiro ano do ensino superior

O fenómeno de massificação do Ensino Superior que surgiu décadas atrás, tem colocado em relevância o tema da adaptação dos estudantes ao novo contexto universitário. As instituições de Ensino vêem-se confrontadas em se adaptar as exigências de uma população estudantil heterogénea. Por outro lado, os estudantes deparam-se com inúmeros desafios que apelam a uma maior autonomia no sentido de uma melhor adaptação à mudança. No presente estudo, pretende-se essencialmente analisar a influência do locus de controlo na adaptação dos alunos do primeiro ano de Ensino Superior do Instituto Superior Miguel Torga. Noventa e três alunos concordaram em participar no preenchimento de dois questionários, o Questionário de Vivências Académicas (versão reduzida), QVA-r (Almeida, Soares & Ferreira, 1999) e a escala I-E de Rotter (1966). Os resultados apontam para a existência de uma correlação negativa entre o locus de controlo externo e a adaptação, sugerindo que quanto mais externo é o tipo de locus de controlo menor é a adaptação do indivíduo. Ademais, também foram encontradas relações entre algumas variáveis sócio-demográficas na adaptação dos alunos do primeiro ano. / The massification phenomena of Higher Education, appeared decades ago, it has emphasized the theme of students adaptation to the new college context. The Teaching institutions are confronted with new demands of a more and more heterogeneous student population. On another hand, students come across with countless challenges, urging to a greater autonomy towards a better changing adaptation. At the present study, it is essentially intended to analyze the locus of control influence in the adaptation of Higher Education first year students, in Instituto Superior Miguel Torga. Ninety three students agreed to participate and fill in two questionnaires, Questionário de Vivências Académicas (short version) (Almeida, Soares & Ferreira, 1999) and Rotter´s I-E scale (1966). The results, point to the existence of a negative correlation between external locus of control and adaptation, suggesting the more external is the locus of control, the less is individual adaptation. Furthermore, it has also been found relations between some socio-demographic variables in first year student’s adaptation.

Villes mortes, villes à l’agonie: Écriture du ravage dans Le quatrième mur de Sorj Chalandon

Dándole un nuevo significado al tópico de la ciudad muerta, especialmente productivo en la literatura de fin de siglo, Sorj Chalandon configura, en Le qua-trième mur, una poética del saqueo que hace de la ciudad devastada un espacio de creación, al mismo tiempo novelesco y trágico, donde reinventar el género de la tumba.

Vandetanib for the Treatment of Advanced Medullary Thyroid Cancer Outside a Clinical Trial: Results from a French Cohort

International audience

The European Registered Toxicologist (ERT): Current status and prospects for advancement

Following its inception in 1994, the certification of European Registered Toxicologists (ERT) by EUROTOX has been recognized as ensuring professional competence as well as scientific integrity and credibility. Criteria and procedures for registration are contained in the ERT "Guidelines for Registration 2012". The register of ERT currently has over 1900 members. In order to continue the harmonisation of requirements and processes between national registering bodies as a prerequisite for official recognition of the ERT title as a standard, and to take account of recent developments in toxicology, an update of the ERT Guidelines has been prepared in a series of workshops by the EUROTOX subcommittees for education and registration, in consultation with representatives of national toxicology societies and registers. The update includes details of topics and learning outcomes for theoretical training, and how these can be assessed. The importance of continuing professional development as the cornerstone of re-registration is emphasised. To help with the process of harmonisation, it is necessary to collate and share best practices of registration conditions and procedures across Europe. Importantly, this information can also be used to audit compliance with the EUROTOX standards. As recognition of professionals in toxicology, including specialist qualifications, is becoming more important than ever, we believe that this can best be achieved based on the steps for harmonisation outlined here together with the proposed new Guidelines.

Sustained release of TGF-β1 from biodegradable microparticles prepared by a new green process in CO2 medium

International audience

Optimizing Western Blots for the Detection of Endogenous α-Synuclein in the Enteric Nervous System

International audience

O protagonista multifacetado : uma leitura pós-moderna de Estorvo e Budapeste, de Chico Buarque

Dissertação (mestrado)—Universidade de Brasília, Instituto de Letras, Departamento de Teoria Literária e Literaturas, Programa de Pós-Graduação em Literatura, 2015.

Naturally Occurring Resistance-Associated Variants of Hepatitis C Virus Protease Inhibitors in Poor Responders to Pegylated Interferon-Ribavirin

International audience

Complete Genome Sequence of the Hyperthermophilic and Piezophilic Archeon Thermococcus piezophilus CDGS T , Able To Grow under Extreme Hydrostatic Pressures

We report the genome sequence of Thermococcus superprofundus strain CDGST, a new piezophilic and hyperthermophilic member of the order Thermococcales isolated from the world’s deepest hydrothermal vents, at the Mid-Cayman Rise. The genome is consistent with a heterotrophic, anaerobic, and piezophilic lifestyle.

CMS Collaboration

SCOPUS: ar.j

Recessive Mutations in RTN4IP1 Cause Isolated and Syndromic Optic Neuropathies

International audience

Directive Cadre sur l’Eau : les pressions anthropiques et leur impact sur les indicateurs de l’état écologique des masses d’eau littorales de la façade Manche-Atlantique - Développement d’une base de données quantitatives sur les pressions anthropiques littorales

Within the European water framework directive (WFD), the status assessment of littoral waters is based both on the chemical quality and on the ecological quality of each water body. Quality elements enabling to assess the ecological status of a water body are, among other things, biological quality elements (phytoplankton, macroalgae, angiosperms, benthic invertebrates, fish), for each of which member states have developed quantitative indicators. This document compiles three deliverables of a multi-annual study intended to characterize the sensitivity of these biological indicators regarding the various anthropogenic pressures exerted on the French Atlantic and Channel coast: ultimately, the goal is to establish a quantitative and predictive relationship, statistically robust, between the WFD indicators used along the French channel and Atlantic coastline, and various anthropogenic pressures acting on these coasts. These three deliverables are the following : - The reports of various interviews performed with French national referents for the biological quality elements used within the littoral part of the WFD in Channel and Atlantic (phytoplankton, subtidal and intertidal macroalgae, opportunistic blooming macroalgae, angiosperms and benthic invertebrates). These interviews aimed to specify, for each metric constitutive of the BQE indicator (if multi-metric), the "relevant" pressures, as well as the trend of this impact, - Sheets describing the "pressure" and "environment" data available, in order to characterize spatially and quantitatively these "relevant" anthropogenic pressures acting on French Channel and Atlantic coast, - A progress report dealing with the development of a database tool, for archiving quantitative data characterizing "relevant" littoral anthropogenic pressures.

On the quality of acoustical measures when evaluating fruits quality

International audience

Prevalence of SOS-mediated control of integron integrase expression as an adaptive trait of chromosomal and mobile integrons

BACKGROUND Integrons are found in hundreds of environmental bacterial species, but are mainly known as the agents responsible for the capture and spread of antibiotic-resistance determinants between Gram-negative pathogens. The SOS response is a regulatory network under control of the repressor protein LexA targeted at addressing DNA damage, thus promoting genetic variation in times of stress. We recently reported a direct link between the SOS response and the expression of integron integrases in Vibrio cholerae and a plasmid-borne class 1 mobile integron. SOS regulation enhances cassette swapping and capture in stressful conditions, while freezing the integron in steady environments. We conducted a systematic study of available integron integrase promoter sequences to analyze the extent of this relationship across the Bacteria domain. RESULTS Our results showed that LexA controls the expression of a large fraction of integron integrases by binding to Escherichia coli-like LexA binding sites. In addition, the results provide experimental validation of LexA control of the integrase gene for another Vibrio chromosomal integron and for a multiresistance plasmid harboring two integrons. There was a significant correlation between lack of LexA control and predicted inactivation of integrase genes, even though experimental evidence also indicates that LexA regulation may be lost to enhance expression of integron cassettes. CONCLUSIONS Ancestral-state reconstruction on an integron integrase phylogeny led us to conclude that the ancestral integron was already regulated by LexA. The data also indicated that SOS regulation has been actively preserved in mobile integrons and large chromosomal integrons, suggesting that unregulated integrase activity is selected against. Nonetheless, additional adaptations have probably arisen to cope with unregulated integrase activity. Identifying them may be fundamental in deciphering the uneven distribution of integrons in the Bacteria domain.