990 resultados para Bruxelles (Belgique)
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info:eu-repo/semantics/published
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We report the case of a 49-year old woman with an idiopathic pulmonary fibrosis (IPF) initially diagnosed as a systemic lupus erythematosus. The IPF is an uncommon clinical entity with an estimated prevalence from 3 to 6 cases per 100,000 in the general population of the United States. This disease is characterised by an insidious onset, a pejorative course and poor survival prognosis (median survival: 2.8 years). The diagnosis is often difficult and depends on the exclusion of other diseases associated with interstitial lung injury. It is generally established only after collegial coordination between the clinician, the radiologist and the pathologist. New consensuses are now published to establish a clear and explicit classification of the IPF. Moreover, because of the poor results obtained with conventional immunosuppressive drugs, new treatments are proposed.
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Etude d'un document inédit où serait mentionnée une femme scribe de village.
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Édition d'un reçu de taxe copte inédit des Musées royaux d'Art et d'Histoire de Bruxelles. Réédition de deux reçus de taxe similaires. Corrections à d'autres textes déjà édités. Les documents proviennent de la région thébaine et datent de la première moitié du 8e siècle.
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Étude de la formule épistolaire :« c'est votre serviteur qui ose écrire à son Seigneur ». Cette tournure, utilisée aux VIIe et VIIIe siècle, est caractéristique de Moyenne-Égypte. Corrections à plusieurs papyrus présentant cette formule. Publication d'un papyrus inédit de Bruxelles présentant cette tournure épistolaire.
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SCOPUS: ar.j
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info:eu-repo/semantics/published
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info:eu-repo/semantics/published
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info:eu-repo/semantics/published
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Severe primary immunodeficiencies (PID) are rare; their global incidence is comparable to that of childhood leukemia; they include more than 100 different entities. Clinical manifestations are: unusually severe or frequent infections or infections that do not respond to adequate treatment; an increased risk of certain malignancies; sometimes auto-immune manifestations. Delayed diagnosis and management of PID can lead to severe and irreversible complications or to death. PID can become manifest only in the adult; in common variable immune deficiency, the median age at diagnosis is between the 2nd and the 3rd decade of life. PID are often transmitted genetically; recent progresses in molecular biology have allowed more precise and earlier, including antenatal, diagnosis. Molecular treatment of 3 infants with a severe immunodeficiency has recently been achieved in April 2000. Those progresses were mostly based on the study of immunodeficiency databases. We present here the work of a Belgian group specialized in PID; meetings have started in June 1997. This group establishes guidelines for the diagnosis and treatment of PID, adapted to the local situation. The elaboration of a national register of PID is also underway; this has to provide all guaranties of anonymity to patients and families. Such a register already exists at the European level; it has provided the basis for new diagnostic and therapeutic possibilities. The inclusion of Belgian data in this register should allow essential progresses essential for our patients.
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Since 1968, bone marrow transplantation became the first line therapy for selected metabolic and immunological hereditary disorders. Actually, advances in the supportive care in bone marrow transplantation and a better knowledge of the immunology of BMT complications has been associated with a better disease correction and an increase in long term survival. New approaches are under investigation and include: hematopoietic growth factors, enzymatic replacement and gene therapy. However at the present time BMT is still the only curative treatment for selected hereditary disorders.
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Bruxelles/New-Haven
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Bruxelles/New-Haven
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SCOPUS: re.j
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SCOPUS: ar.j
