1000 resultados para sumea säätö


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Lisäpainokset: 2. p. 1901 (619 s.).

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Despite its ancient use as a therapeutic tool to treat several ailments, acupuncture still faces the challenge of scrutiny by Western science both in terms of its efficacy and in terms of the characterization of its effects and mechanisms of actions underlying these effects. We investigated under well-controlled and carefully characterized conditions the influence of electrical stimulation of acupuncture points ST-36 (Zusanli) and SP-6 (Sanyinjiao) on the myoelectric activity of the small intestine of 38 adult male Wistar rats. Electrical recordings obtained by means of four electrodes chronically implanted in the small intestine were used to assess the effects of acupuncture (electroacupuncture stimulation set at 2 Hz, intermittent stimulation, 1 V, for 30 min). Immobilization of the animals was associated with a consistent decrease (-8 ± 7%) in the myoelectric activity of the small intestine as measured by means of the root mean square. Conversely, acupuncture was able to significantly increase (overshoot) this activity compared to baseline (+44 ± 7%). In contrast, immobilized animals subjected to sham acupuncture had only modest (nonsignificant) increases in myoelectric activity (+9 ± 6%). Using carefully controlled conditions we confirmed previous noncontrolled studies on the ability of acupuncture to alter intestinal motility. The characterization of the topographic and temporal profiles of the effects observed here represents a basis for future dissection of the physiological and pharmacological systems underlying these effects.

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We have investigated the hypoglycemic effect induced by the starch obtained from the unripe fruits of Solanum lycocarpum (Solanaceae). Per os administration of the starch (1000 or 2000 mg/kg, twice daily for 7 days, N = 6) did not change glycemia levels of nondiabetic female Swiss mice weighing 25-30 g. In streptozotocin-induced diabetic mice, similar treatment with the starch did not change the elevated glycemia 3 h after the last dose (diabetic treated with saline = 288 ± 17/309 ± 18; starch 1000 mg/kg = 295 ± 33; starch 2000 mg/kg = 258 ± 37; N = 5). In animals fasted for 15 h, per os administration of glucose (600 mg/kg) significantly increased glycemia 1 h later. Previous (-30 min) treatment of the animals with the starch (1000 or 2000 mg/kg; N = 5) did not change the increase of glycemia. Per os administration of the starch (1000 or 2000 mg kg-1 day-1, twice daily for 7 days) did not induce body weight gain or loss. The chemical analysis of the starch indicated the presence of glycoalkaloids, a finding that represents a reason for concern since many of these substances are generally toxic. In interviews with 56 diabetic patients, 29 medicinal plants were reported as useful in their treatment of diabetes and S. lycocarpum was the sixth most frequently mentioned. All patients interviewed reported that they also used insulin or oral hypoglycemic drugs. The results of the present study do not provide evidence for a hypoglycemic effect associated with the polysaccharide fraction of S. lycocarpum in either normal or hyperglycemic mice. These data demonstrate the need for adequate pharmacological investigation of the natural products widely used in folk medicine.

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Kartta kuuluu A. E. Nordenskiöldin kokoelmaan

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Presentation of Janet Aucock, at the FinELib Consortium Seminar (Aineistopäivä), April 16, 2015 in Helsinki.

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0-meridiaani: Greenwich.

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[N. 1:730000].

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Endothelial function (EF) plays an important role in the onset and clinical course of atherosclerosis, although its relationship with the presence and extent of coronary artery disease (CAD) has not been well defined. We evaluated EF and the ST segment response to an exercise test in patients with a broad spectrum of CAD defined by coronary angiography. Sixty-two patients submitted to diagnostic catheterization for the evaluation of chest pain or ischemia in a provocative test were divided into three groups according to the presence and severity of atherosclerotic lesions (AL): group 1: normal coronaries (N = 19); group 2: CAD with AL <70% (N = 17); group 3: CAD with AL ≥70% (N = 26). EF was evaluated by the percentage of flow-mediated dilatation (%FMD) in the brachial artery during reactive hyperemia induced by occlusion of the forearm with a pneumatic cuff for 5 min. Fifty-four patients were subjected to an exercise test. Gender and age were not significantly correlated with %FMD. EF was markedly reduced in both groups with CAD (76.5 and 73.1% vs 31.6% in group 1) and a higher frequency of ischemic alterations in the ST segment (70.8%) was observed in the group with obstructive CAD with AL ≥70% during the exercise test. Endothelial dysfunction was observed in patients with CAD, irrespective of the severity of injury. A significantly higher frequency of ischemic alterations in the ST segment was observed in the group with obstructive CAD. EF and exercise ECG differed among the three groups and may provide complementary information for the assessment of CAD.

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Kädessäsi oleva opas on laadittu yleisoppaaksi jokaiselle Maanpuolustuskorkeakoulun tutkinto-opiskelijalle ja muille lukijoille opas on hyvä tietolähde. Yleisessä osassa esitetään opiskelijoille perustietoutta Maanpuolustuskorkeakoulusta, opiskelusta ja tutkinnoista. Oppaassa on asiaa koskien jokaista Maanpuolustuskorkeakoulun opiskelijaa, viranomaisyhteistyön koulutusohjelma ja tohtoriopiskelijat mukaan luettuna. Oppaasta löytyy tarpeellista tietoa muun muassa opintohallinnosta, opiskeluoikeuksista ja opintoneuvonnasta sekä toimimisesta Santahaminan sotilasalueella. Yleisen osan lisäksi opiskelijan on tunnettava opinto-oppaan eriytyvät osat ja niihin sisältyvät oman tutkintotasosi opintojaksokuvaukset. Lue opinto-oppaat huolella. Näin saat kokonaisvaltaisen kuvan tulevien vuosiesi työskentelystä ja opintojesi tavoitteista. Yksityiskohtaisempia tietoja saat kurssinjohtajalta, oman tutkintotasosi koulutussuunnittelijalta ja ainelaitoksilta. Oppaaseen on koottu opiskeluun liittyviä tärkeitä yhteystietoja helpottamaan opiskelijan arkea. Oppaasta löytää myös Santahaminan kampusalueen kartan. Jos et saa oppaasta tarvitsemaasi tietoa, tai jos jokin asia jää sinulle epäselväksi, otathan yhteyttä Opintoasiainosaston henkilökuntaan. On myös toivottavaa, että annat palautetta opinto-oppaasta Opintoasiainosaston henkilöstölle. Näin voimme kehittää opasta edelleen.